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Tag: "tied" at biology news

Free-energy theory borne out in large-scale protein folding

...otein's function, because function is inextricably tied to shape, and every protein self-assembles into its characteristic shape within seconds of being created. "The folded, functional form of the protein is what really matters, and our interest is in creating a folding roadmap of sorts, a plot of the t...

MIT researcher finds neuron growth in adult brain

...hanges," Nedivi said. "What's more, this growth is tied to use, so even as adults, the more we use our minds, the more robust they can be." ...

Life in deadly conditions

...e, genetic and protein data about the organisms is tied to information about their structure and function. The newest genome on HaloLex is now that of Natronomonas pharaonis, whose genetic information was made available by Michaela Falb, Friedhelm Pfeiffer, Peter Palm, Karin Rodewald, Volker Hickmann, J?T...

Scientists use gene transfer technology and common virus to block neuropathic pain

...n the Annals of Neurology paper, VA/U-M scientists tied off a nerve root in the sciatic nerve leading to the left hind paw of eight rats in the study. Tying off the nerve root makes the nerve degenerate and release substances that cause pain, according to Fink. A second group of eight rats received sham s...

Scientists use gene transfer technology and common virus to block neuropathic pain in animals

...n the Annals of Neurology paper, VA/U-M scientists tied off a nerve root in the sciatic nerve leading to the left hind paw of eight rats in the study. Tying off the nerve root makes the nerve degenerate and release substances that cause pain, according to Fink. A second group of eight rats received sham s...

Monkeys understand numbers across senses

...al values by nonhuman animals or human infants was tied to the sense used to perceive the number. To resolve the question, said Brannon, the researchers decided to design an experiment that used socially relevant stimuli. "Our approach really derives from thinking about why a monkey would need to represe...

Once given 'no respect,' cells' tiny RNAS take driver's seat

...oRNAs in a region of chromosome 13 that is already tied to development of human lymphoma. MicroRNAs are made by the same cellular machinery that makes other forms of RNA -- like the messenger RNA used to build proteins. However, microRNAs are immediately processed by cellular machinery that deals with wh...

Beyond genes: Lipid helps cell wall protein fold into proper shape

...s. Dowhan estimates another 40 percent are loosely tied to membranes. "So you are looking at possibly 70 percent of biology occurring at or in a lipid membrane surface," Dowhan said. Membranes and their surface proteins are accessible targets for pharmaceuticals, and most drugs target either membrane pro...

New lifespan extension genes found

New genes tied to lifespan extension in yeast have been identified by researchers from UC Davis and Harvard Medical School. Drastically reducing calorie intake, or caloric restriction, is known to extend the lifespan of species including yeast, worms and rodents. ...

Researchers identify new genes that regulate aging

...sen M, Hsu AL, Dillin A, Kenyon C (2005) New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. PLoS Genet 1(1): e17. ...

15-year hunt finds cause of pseudothalidomide syndrome

... find better funding opportunities. In Japan, Vega tied the Colombian families' syndrome to a large region...18 affected members and 33 unaffected members) and tied the condition to one of 6 genes. Then, the international team compared the human sequence of the ge...

Defenseless plants arm themselves with metals

...om metal. Because the production of glutathione is tied to the production of salicylic acid, most plants normally have fairly low glutathione levels and, consequently, can't tolerate metals. Thlaspi, on the other hand, is brimming with glutathione, thanks to its elevated salicylic acid levels. When grown...

Navigating an integrated yeast network

...of interactions between macromolecules that can be tied to biological phenomena and may help represent more fundamental network design principles than do simple motifs. Zhang et al. integrated five different types of biological relationships found in the yeast Saccharomyces cerevisae: protein-protein int...

Biodiversity hotspots identify conservation priorities

...lso for the millions of people whose well-being is tied to its ecological health." The Madrean Pine-Oak Woodlands hotspot is a 178,095-square-mile area encompassing Mexico's main mountain chains, some isolated mountaintops in Baja California, and a few scattered patches in the southern United States (rep...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

...cells throughout the body, including those closely tied to brain disorders, cardiac illness, and other major conditions. He pointed out that clathrin is also important to cellular mechanisms other than endocytosis, including those occurring deep inside the cell. "Now that we have a better handle on this...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...ng a mutation in a gene called APC, which had been tied to colon cancer by researchers studying families with excessive growths, or polyps, in the colon. Mice with extra IGF2 and the APC mutation developed twice the number of tumors as mice with the mutation but whose IGF2 levels were normal. The tumors ...

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