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Tag: "tied" at biology news

Individuals and populations differ in gene activity levels, not just genes

...andom differences between individuals, and was not tied to ancestral population or biological "race." "It's important to remember that differences between population groups are much less abundant than those you would see if you just compared two randomly selected individuals," said Storey. "This means...

Scientists map key landmarks in human genome

...cleosomes, rather than in the DNA regions that are tied up by the nucleosome complexes. These results suggest that nucleosome positioning controls the turning on or off of genes, and the nucleosomes can be relocated if cellular needs change. Fisher, who heads Dana-Farber's Melanoma Program and is a pro...

Statin plus cancer drug deliver combo punch to brain cancer cells

...ulloblastoma cells and another cell signal already tied to cancer, Bcl-2. Eberhart and his team believed that combination of a hedgehog blockade and a pro-apoptosis drug like lovastatin would kill more cancer cells. "Our experiments suggest that hedgehog's action is woven together with Bcl-2, best know...

Ape gestures offer clues to the evolution of human communication

...ween species the manual gestures were less closely tied to a particular emotion and, thereby, serve a more adaptable function. For example, a single gesture may communicate an entirely different message depending upon the social context in which it is used. "A chimpanzee may stretch out an open hand t...

How mammals fuel milk production may have implications for cancer

...one of the few scenarios in which metabolism isn’t tied to the proliferation or growth of cells,?Chodosh said. “The breast is an unusual organ that’s essentially a synthetic factory for milk. There’s nothing else like it.? During a typical 21-day course of lactation, a mouse will produce its entire bod...

LSD treatment for alcoholism gets new look

... the patients in isolation, so they blindfolded or tied up the patients before giving them the drug. Under such circumstances, the Toronto researchers determined LSD was not effective in treating alcoholism. The Saskatchewan group argued that the drug needed to be provided in a nurturing environment to...

Scientists explore how complex organs develop from a simple bud

...e into tubulogenesis ?a process that is intimately tied to branching morphogenesis. Another contains research aimed at helping patients whose salivary glands have been injured by radiation therapy or autoimmune rejection. An investigation into the morphogenesis of the prostate gland and seminal vesicles i...

A new target for painkillers

...s. For the study, the North Carolina co-authors tied sutures loosely around one of each rat's two sciatic nerves to mimic nerve compression and injury from sciatica. That made the rats overly sensitive to touch on one hind paw but not the other. Each rat's sensitivity was assessed by measuring how much...

Slow brain waves play key role in coordinating complex activity

...lar or larger on the surface of the cortex, and is tied to top-down executive processes like attention and memory. Coupling between these two rhythms could be what gives the brain a way to connect low-level perceptions and actions to high-level goals and intentions." Brain waves - such as the slow alpha ...

Batfish to the rescue!

...the resilience of inshore GBR reefs may be closely tied to the fate of mangroves and their suitability for batfish recruitment." Batfishes may be one of the last intact herbivore populations capable of reversing serious weed overgrowth of inshore coral reefs, he adds. The reef has already all-but lost ...

Study suggests evolutionary link between diet, brain size in orangutans

...short intervals between births could themselves be tied to smaller brains in such higher primates as orangutans, van Schaik and Taylor wrote in their current report. "Larger-brained apes have slower-paced life histories," they said. "Assuming selection is acting on brain size, life history is prolonged ...

Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation

...herosclerosis and vascular inflammation, which are tied together," said Prediman K. Shah, M.D., director of the Division of Cardiology and the Atherosclerosis Research Center at Cedars-Sinai. "We used a unique approach to do a head-to-head comparison, which allowed us to conclusively ascertain the diff...

Precision biochemistry tracks DNA damage in fish

... revealed similar damage to liver DNA (more likely tied to the fish's food) and gill DNA (more probably reflecting pollutants in water). The results suggest that these DNA lesions, and others like them, can be used as very sensitive biomarkers to provide a direct measure of the impact of contaminants on ...

Research tracks whales by listening to sounds

...nce is really striking, but we don't know if it is tied to genetics, or some other reason. "There are also some hybrid sounds that are rare," he added. "We don't know if they are part of a common 'language' that different populations of whales use to communicate with each other, or if they come from a co...

Study may help slay 'Yellow Monster'

...fter graduation. The funding for Stearns' work is tied to improving health among Native American communities. Stearns is the NAU principal investigator of a grant jointly awarded to NAU and the Arizona Cancer Center by the National Cancer Institute. Louise Canfield is the principal investigator on the gr...

ASU researchers find link between social behavior, maternal traits in bees

...ut, furthering the case that foraging behavior was tied to reproductive traits. Amdam then put her results to a crucial test -- wild-type bees (bees that had not been used in the experiment) were captured after their first foraging flight. Amdam and her team recorded what the bees brought back from the f...

Molecular force field helps cancer cells defend against attack

...owth factor receptor 3, or VEGFR-3. The protein is tied to the growth of channels in the lymph system that serve as cellular superhighways for cancer spread and is found in breast, colon and thyroid tumors. Cance and colleagues were the first to pull FAK out of human tumors and to show that human cancers...

Gut protein found to protect against infection and intestinal breakdown

...he environment." When the bile ducts of mice were tied off, preventing bile from reaching the intestine, adding GW4064 prevented damage to the intestines, showing that it can replace bile in protecting the small intestine. Genetically engineered mice that lacked FXR showed overall damage to the intesti...

Light activated anticancer drug targeted to DNA using cisplatin like sub-units

...re working on cisplatin analogs before, so we have tied it to light activated systems." Cisplatin begins its interaction with cancer DNA by binding to the nitrogen atoms of the DNA bases, typically guanine. Our new supramolecules use this nitrogen-binding site to hold the light activated drug at the targ...

Horseshoe crab decline threatens shorebird species

...mber of red knot birds throughout the Delaware Bay tied to a decline in horseshoe crabs. The research will be reported in The Journal of Wildlife Management, in the article, "Horseshoe Crab Eggs Determine Red Knot Distribution in Delaware Bay Habitats," by Virginia Tech fisheries and wildlife research sc...

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