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Tag: "throughput" at biology news

NIH neuroscience microarray consortium launches high-throughput genotyping services

...investigator at UCLA, says that "adding ultra-high throughput genotyping for its user-base of ~10,000 investigat...s Neurogenomics Division. "Implementing these high throughput genotyping services will ultimately make a dramatic impact in clinical care of neurological disorder...

NHGRI aims to make DNA sequencing faster, more cost effective

...o-sized features, a DNA nanoarray can also improve throughput by offering the ability to accommodate billions of DNA molecules in a small area. Hybridization will be detected by atomic force microscopy. Carlos H. Mastrangelo, Ph.D., Case Western Reserve University, Cleveland,$815,000 (3 years),"Large-Scale ...

The power of one: A simpler, cheaper method for cell fusion

... that his device may be developed to have a higher throughput than current methods. Although Lu's technology currently fuses single pairs at once, it may be expanded so that multiple devices simultaneously fuse cells in parallel. "In time, this could drastically increase the rate of cell fusion," he said. ...

Spelling out cancer on the nanoscale

...to individual patients. Finally, we provide a high throughput method to identify if new cancer drugs are effective at targeting specific oncoproteins." ...

New method enables gene disruption in destructive fungal pathogen

...scientist and author of the paper, said, "The high throughput system described in this study should allow for the systematic analysis of large sets of candidate genes in A. brassicicola, such as those encoding cell-wall-degrading enzymes and other genes of interest in pathogen-plant interactions." The new gene...

Study suggests that publicly available genome data may contain small but significant errors

...Laboratory and New York University describe a high throughput microarray technique that involves testing many samples simultaneously and which can be used to assemble physical maps and validate genomic sequence assemblies. The findings appear in the latest issue of the Journal of Computational Biology. The...

Technique offers new view of dynamic biological landscape

...d kill the cell -- the researchers invented a high throughput technique to manipulate the half-life of their messenger RNA (mRNA). Since mRNA is a genetic intermediate during the conversion of a gene to protein, reducing its lifespan by mutating the mRNA message lowers the amount of protein the cell can produce...

Hopkins scientists uncover 'tags' that force proteins to cell surface

... through -- 25 billion or so -- given today's high throughput technologies. To make it even easier, Shikano developed a system that would separate the wheat from the chaff before the analysis began -- if the protein wasn't taken to the cell surface by the tag, the cell died. "If the protein went to the cell s...

New mitochondrial DNA gene chip may be early cancer diagnosis tool

...be faster, easier to interpret, and provide higher throughput than other methods. A paper describing the NCI-NIST work appears in the May issue of the Journal of Molecular Diagnostics. ...

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

...ucture-based virtual screening techniques and high throughput equipment to screen for potential inhibitor compounds against the Dam enzyme. ...

CoPub Mapper: mining MEDLINE based on search term co-publication

High throughput microarray analyses result in many differentially expressed genes that are potentially responsible for the biological process of interest. In order to identify biological similarities between genes, publications from MEDLINE were identified in which ...

Open microfluidic and nanofluidic systems

...cessing. In general, this should lead to increased throughput and, thus, to reduced cost of (bio)chemical analysis. In addition, such integrated labs-on-a-chip have many potential applications in biomedicine and bioengineering. In the context of biomedicine, for example, they could provide fast and detailed ana...

Learning to fight an adversary that won't stay down

...e. Techniques such as genomic sequencing and high throughput screening were expected to make the development of new antibiotic compounds easier and more productive. But in most cases the microbes continue to hold the upper hand ?and if three billion years of bacterial history is any kind of track record, we're...

Tiny particles could solve billion-dollar problem

...e catalyst will be efficient enough to provide the throughput needed to make the whole approach effective. Tests in Wong's lab have found that the gold-palladium nano-catalysts break TCE down about 100 times faster than bulk palladium catalysts. ...

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