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Growth in the sea comes down to a struggle for iron

...ying the possibility that small variations in iron throughout the world's oceans may have important ecological consequences as well. Their results will contribute to the diverse oceanographic understanding needed to determine whether or not adding iron to ocean waters is a wise tool in any attempts to manage a ...

Gene variations explain drug dose required to control seizures

...ne anti-epileptic drugs that are widely prescribed throughout the world, Goldstein said. Both drugs commonly spur adverse reactions. "Physicians have long recognized that patients with the same condition differ in their responses to the same drugs," said neurologist and epilepsy specialist Sanjay Sisodiya, M.D...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...source. As a result, glycogen builds up in muscles throughout the body, including the heart, causing muscles to degenerate. Using genetically altered mice in which the gene for the enzyme had been rendered nonfunctional, the researchers demonstrated they could introduce the functioning gene and correct glycoge...

Enzyme shown to help protect genomic stability

Genomes throughout the animal kingdom and beyond are characterized by extensive segments that are inactive, lengthy stretches of DNA containing multiple genes that are closed to gene transcription. Scientists believe one reason for this broad gene silencing is the vita...

First 'atlas' of key brain genes could speed research on cancer, neurological diseases

...F genes were expressed inspecific regions, and not throughout the brain, as the majority were.They inferred that these 349 genes, therefore, controlled thedevelopment of the particular areas or structures in which they wereuniquely expressed.Stiles is pursuing TF’s that direct the formation of astrocytes, which...

Vital step in cellular migration described by UCSD medical researchers

...ves toward its intended target. If Rac were active throughout the cell, it would extend protrusions in all directions, in essence keeping the cell in one place. Until now, researchers have had limited understanding of the molecular mechanism that inhibits Rac activity in the back of the cell, to maintain direc...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

...rain alive. Every one of these cells -- and others throughout the body -- depends on an internal process called ...aid the findings have broad implications for cells throughout the body, including those closely tied to brain disorders, cardiac illness, and other major conditio...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...o compounds that zero in on cancer cells spreading throughout the body, while ignoring primary tumor cells, could someday give doctors a whole new weapon in the fight against tough-to-treat metastatic disease, according to Weill Medical College of Cornell University researchers. The compounds, called synthetic...

Study: Soap And Water Work Best In Ridding Hands Of Disease Viruses

...quire traditional hand washing with soap and water throughout each day. Researchers first had volunteers clean their hands and then contaminated their hands with Serratia marcescens and MS2 bacteriophage. Those are, respectively, a harmless bacterium and virus comparable to, and substituted for, disease-causin...

Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra

...s how the effects of introduced species can spread throughout an ecosystem in unpredictable ways," said Donald Croll, an assistant professor of ecology and evolutionary biology at the University of California, Santa Cruz, and first author of the Science paper. Efforts by the U.S. Fish and Wildlife Service to r...

Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems

...ptimal performance on tests of learning and memory throughout life," they said. "Growth hormone/IGF-1 replacement in older animals reverses the age-related decline in cognitive function." The group also found that "cartilage degeneration that normally accompanies aging is accelerated by the absence of growth h...

Zebrafish may hold key to understanding human nerve cell development

...d also play a role in the development of stemcells throughout the nervous system. Much more research is needed toidentify this signal but we're optimistic our work has set the stagefor future discoveries," said Piotrowski.The University of Utah has one of the largest zebrafish facilities inthe country with more...

Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined

...d also play a role in the development of stemcells throughout the nervous system. Much more research is needed toidentify this signal but we're optimistic our work has set the stagefor future discoveries," said Piotrowski.The University of Utah has one of the largest zebrafish facilities inthe country with more...

GenMAPP 2.0 released

...d also play a role in the development of stemcells throughout the nervous system. Much more research is needed toidentify this signal but we're optimistic our work has set the stagefor future discoveries," said Piotrowski.The University of Utah has one of the largest zebrafish facilities inthe country with more...

UCLA scientists transform HIV into cancer-seeking missile

... This allowed the virus to infect cells and spread throughout the body without provoking disease. "The disarmed AIDS virus acts like a Trojan horse ?transporting therapeutic agents to a targeted part of the body, such as the lungs, where tumors often spread," said Chen, a professor of medicine, microbiology, i...

Beyond lithium for bipolar disorder

... risk of bipolar disorder. PACAP protein is found throughout the central nervous system, said the researchers. They cited studies demonstrating that mice in which the gene is knocked out show hyperactivity and defects in their circadian (day-night) behavior--both also characteristic of humans with bipolar diso...

FDA Warns Consumers Not to Use Home-Use Diagnostic Kits Marketed by Globus Media

...e tests were sold through websites and distributed throughout the U.S., usually by overnight delivery services. These have been made available for sale on several websites, including www.htkit.com and www.hstkits.com. The kits usually are contained in a paper envelope with instructions inside the packaging. The...

Scientists identify new model Of NK cell development

...e novel NK precursor cells are not randomly strewn throughout the lymph nodes, but rather localized near special sites called parafollicular regions, rich in T cells and NK bright cells. "We thought this was pretty interesting because we know that in order for these NK precursor cells to grow and differentiate...

Unexpressed But Indispensable -- The DNA Sequences That Control Development

...ertebrate chordate. CNEs are not spread uniformly throughout the genome. Instead, they are bunched together in fewer than 200 clusters, most of them in close proximity to genes implicated in transcriptional regulation or development. This clustering of CNEs suggests they may not only attract transcription fact...

Photos show jaguar vamping for camera

...Conservation Society is working to protect jaguars throughout their range with projects in several Latin American countries designed to safeguard healthy populations of this spectacular big cat. ...

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