Gene that makes people 'early to bed and early to rise' demystified
...at UCSF. Based on those studies, "everybody had thought a short or long period depended on a change in protein stability," she said. "That's how we thought the system should work. But this paper shows that is not the case. It comes back instead to the tran...White blood cells in lung produce histamine seen in allergies
... Francisco VA Medical Center. "Previously it was thought that the primary sources of lung histamine, in hea...tions of infected mice developed pneumonia. "We thought the mice without mast cells would do better than the wild-type mice, because the infection wouldn't ...Prenatal cocaine's lasting cellular effects
... cause these subtle cognitive impairments. "We thought that it was important to set up an animal model that recapitulates a key feature of human abuse -- that being intravenous exposure to low doses of cocaine," Stanwood said. A few years ago, Stanwood and Levitt, professor of Pharmacology and direct...A case of mistaken identity for the ivory-billed woodpecker?
...cess journal BMC Biology shows how fleeting images thought to be the Ivory-billed Woodpecker Campephilus prin...hite species. The Pileated Woodpecker's wings were thought to beat more slowly that the 8.6 beats per second captured on Luneau's video, and its wings have bla...Selective marker found to indicate aggressive form of breast cancer
...sts do not know its exact function, the protein is thought to have a role in stabilizing the structure of adult stem cells as they regenerate and divide into daughter cells. "Normal basal epithelial tissue produces nestin, but basal epithelial tumors produce a tremendous amount of nestin, which likely r...Racing neurons control whether we stop or go
...els can be used to discover how the brain produces thought and action." Vanderbilt psychologists Leanne Boucher, Thomas Palmeri, Gordon Logan and Schall published the findings in the April issue of Psychological Review. The new paper uses physiological data collected in Schall’s laboratory to show how...New species declared: Clouded leopard on Borneo and Sumatra
...at. The secretive rainforest animal was originally thought to be the same species as the one found in mainland Southeast Asia. Genetic analysis conducted at the U.S. National Cancer Institute shows that the difference between the two clouded leopard species is comparable to the differences between other l...Trojan horse strategy defeats drug-resistant bacteria
...s. "Because iron is so important in infection, we thought infecting bacteria might be vulnerable to interventions that target iron," explained Yukihiro Kaneko, senior fellow in microbiology at the UW and the study's lead author. To accomplish this, the researchers used gallium, a metal very similar to ir...Stem cells decrease ischemic injury and restore brain function
..., among which the microglia, which has always been thought to have a toxic and inflammatory role. "Instead, we suggest that the microglia also has a protective function,?says De Simoni. “Moreover our research shows that these cells survive in brain tissue only for a few days and then they are eliminated. Thi...Jefferson researchers' discovery may change thinking on how viruses invade the brain
A molecule thought crucial to ferrying the deadly rabies virus into t...in and central nervous system. The LC8 protein was thought to tether viruses to the cellular transport machinery in order to get there. But Dr. Schnell and...Lead with a poisonous electron shield
...ayed a role in the fall of the Roman Empire: it is thought to have been caused by the concentration of grape juice in lead containers. Though the introduction of lead-free gasoline has reduced damage to the environment, the annual production of lead continues to increase worldwide because lead is still used ...Small molecule dervived from Rb2/p130 could act as cancer therapeutic
...e functionality as p21, explained Giordano. "We thought we could narrow down the spacer region that contains the protein-like motif to a small portion that could be delivered as a small molecule or peptide," Giordano said. They discovered a 39 amino-acid-long sequence, which they named Spa310. The mol...The origin of the brain lies in a worm
...me ancestor, but their CNSs are different and were thought to have evolved only after their lineages had split during evolution. Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg now reveal that the vertebrate nervous system is probably much older than expected. The study, which...No sex for 40 million years? No problem
...ual organisms." Previously, many scientists had thought that sexual reproduction was necessary for speciat... scientific understanding, because it is generally thought that asexual creatures die out quickly, but these have been around for millions of years. "Our p...Gene study shows three distinct groups of chimpanzees
...rowth of rivers, such as the Congo River, which is thought to be about 1.5 million years old. "Chimps don't swim," Becquet said. "For them, water provides a very effective border." The ongoing loss of habitat has increased the physical separation between the three groups. The extent of accumulated genet...Largest genomic search finds genes that may contribute to autism
... Inheriting more of these genes or certain ones is thought to increase a child's likelihood of being born with autism or a more severe form of the disorder, just as there are genes that heighten a person's chances for inheriting breast cancer or heart disease. Autism is actually a spectrum of disorders th...New research may overturn conventional wisdom on drug-resistant tuberculosis
...tant to standard therapy. This resistance was long thought to be acquired through mutations in the infecting strain when the treatment regimen was inadequate or the patient did not comply with it. More recently, studies of the genetic make-up of Mycobacterium tuberculosis (M. tuberculosis) strains have shown...DNA analysis reveals rapid population shift among Pleistocene cave bears
...th the arrival of modern humans in the Ach Valley, thought to have occurred by 32,000 years ago. The researchers suggest that human influence in the form of hunting and competition for sheltering caves may represent a plausible explanation for the disruption in the cave bear population, creating an opportuni......prising because dosage compensation was previously thought to be critical for survival. Birds, however, seem to be doing just fine without sexual equality of Z gene expression". ...NIH announces phase III clinical trial of creatine for Parkinson's disease
...herapy for PD or any other condition, it is widely thought to improve exercise performance. The potential benefit of creatine for PD was identified by Parkinson’s researchers through a new rapid method for screening potential compounds. The double-blind, placebo-controlled, phase III study is one of the la...