Genetically modified natural killer immune cells attack, kill leukemia cells
...chnique for genetically modifying NK cells so that they would become potent killers when they encountered leukemic cells. In order to grow large populations of NK cells, the team started with s...UCSD researchers maintain stem cells without contaminated animal feeder layers
...se stem cells were to be transplanted into people, they would provoke an immune system attack eliminating ...ssachusetts, new feeder layers were developed, but they did not entirely eliminate the use of animal products. In the Hayek study, the animal-derived feeder...Transport System Smuggles Medicines Into Brain
...ble for the red colors found in the parrot species they sampled. The researchers used a chemical analysis...nt study on the parrot pigments that suggests that they can act as anti-oxidants to quench free radicals and potentially protect cells and tissues in the bo...Scientists develop new color-coded test for protein folding
...ytochrome c. "We chose gold nanoparticles because they are simple to prepare, easy to control and cost effective," the authors wrote. "To the best of our knowledge, however, gold nanoparticles have not been previously used to investigate the folding and unfolding of proteins." The initial batch of gold-...Placenta Is A Rich Source Of Blood Stem Cells
...cells don't multiply readily in the laboratory, so they must be harvested from bone marrow by needle aspiration, a painful procedure, or coaxed into the blood and then collected. Both methods yield only a limited number of blood stem cells. For more than a decade, scientists have believed that blood stem...Probing The Promise And Perils Of Nanoparticles
...nes more permeable. At high enough concentrations, they can completely destroy the membranes, killing cell...dy being used to deliver drugs and genes—to see if they behaved like dendrimers. "It turns out that they cause the same permeability and, in general, they c...Open microfluidic and nanofluidic systems
...h research is performed in the life sciences since they offer the ability to work with much smaller reagen...ering. In the context of biomedicine, for example, they could provide fast and detailed analysis of blood samples in the physician's office without the need...Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
...he time there are 120 days old. In thisexperiment, they vaccinated the mice three times with VRP-neu, and “nota single mouse developed a tumor,?says Lachman.Lachman suggests the vaccine might prove helpful in keeping humanHER2/neu tumors from metastasizing, or spreading, but adds that thisnotion must be t...Highly adaptable genome in gut bacterium key to intestinal health
... that underlie the stability of the gut ecosystem, they may be able to develop ways to manipulate the gut's bacterial community to promote health or treat diseases. For example, the group is assessing how the bacterial capacity for processing dietary carbohydrates varies among individuals and what influen...Researchers find missing genes of ancient organism
... load in the process of evolution," said Söll. "Or they may represent a specialization that has rid itself of genetic baggage to exist in extreme environments." Understanding how primitive organisms like Nanoarchaea operate gives clues to -- but not proof of -- the relationship between modern and ancient...Amino acids in nectar enhance butterfly fecundity: A long awaited link
...ch stinging nettle. After the butterflies emerged, they were fed nectar with or without amino acids. Butterflies raised under natural, nitrogen poor larval food conditions laid more eggs when fed nectar containing amino acids. These results provide the long missing evolutionary link between costly nectar...Scientists identify genetic pathways essential to RNA interference
...eagues developed a strain of C. elegans into which they added a gene that caused the worms to glow under ultraviolet light but also turned that gene off using RNAi. They then used RNAi to inactivate every one of the worms' 19,000 genes by feeding the worms bacteria that produce double-stranded RNA for eac...A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020
...he time there are 120 days old. In thisexperiment, they vaccinated the mice three times with VRP-neu, and “nota single mouse developed a tumor,?says Lachman.Lachman suggests the vaccine might prove helpful in keeping humanHER2/neu tumors from metastasizing, or spreading, but adds that thisnotion must be t...Same mutation aided evolution in many fish species, Stanford study finds
...uickly evolved into such distinct populations when they colonized new freshwater lakes and streams, they are an ideal model for understanding how animals adapt to their unique environments. The recent wor...Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra
...n archipelago can only support dense grasslands if they receive regular doses of fertilizer in the form of bird droppings. On islands without foxes, seabirds transfer nutrients from the ocean to the land by feeding on marine fish and invertebrates and spreading nutrient-rich guano around the islands. Add ...Researchers trace evolution to relatively simple genetic changes
...ast ice age ended 10,000 to 15,000 years ago. Then they evolved along separate paths, each adapting to the...lating on the stickleback, Kingsley said The gene they identified is called Eda, originally named after a human genetic disorder associated with the ectody...Scientists reveal molecular secrets of the malaria parasite
...ow malaria parasitesevolve on a molecular level as they move between their hosts and insectvectors.That fo...ed that the parasite genes evolve mostrapidly when they are expressed in the mammal hosts (human/mouse). Thatmay represent a mechanism by the parasites to r...Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
...ast ice age ended 10,000 to 15,000 years ago. Then they evolved along separate paths, each adapting to the...lating on the stickleback, Kingsley said The gene they identified is called Eda, originally named after a human genetic disorder associated with the ectody...Studies reveal methods viruses use to sidestep immune system
...ein essential to triggering immune defenses. Again they found that protease inhibitors could reverse the effects of NS3/4A, allowing this immune pathway to be restored to shut down HCV replication. Hepatitis C is a chronic disease that affects 4 million people in the United States, making it the nation's......tabolism of small groups of cells and studying how they respondto drugs, toxins and pollutants. To do so, ...ctengineer David Schaffer. "With our capabilities, they can beginapplying their technology to a goldmine of different applications."One of the key VIIBRE ca...