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Tag: "they" at biology news

Mitochondrial DNA mutations play significant role in prostate cancer

...ten are called the "powerhouse"of the cell because they produce about 90 percent of the body's energy.John...ts andcontrols of European ancestry. In this group they found the COImutations in 11 percent of the prostate cancer specimens, in 0 percentof the no-cancer ...

Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey

...onment for enemies or food. Based onwhether or not they ‘see?other cells, they make the toxinappropriately.?Gilmore says this discovery has several significant implications forthe...

Researchers reveal the infectious impact of salmon farms on wild salmon

...vels of migrating juvenile pink and chum salmon as they approached and passed a salmon farm. Within the st...e scientists could see the effect on the salmon as they moved toward the farm. They found that the juvenile salmon carried almost no sea lice prior to the f...

Molecular machine may lead to new drugs to combat human diseases

...rons reveal their structure and the sites at which they bind with various molecules to cause biochemical r...an health, Group I introns are interesting because they cause their own removal and also splice the ends of the surrounding RNA together, forming a function...

Jefferson Virologists Coax HIV Out of Hiding

...wn as highly active antiretroviraltherapy (HAART), they hoped they had found a way to finally rid thebody of the virus. But they were wrong. The virus instead goes int...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

... with a purified human antibody as a control. Then they added the cat protein that triggers allergic react...tors. These mice were “passively allergic?to cats: they would react to cat protein only after the scientists first injected them with human allergic antibod...

Color-blind method opens new doors in DNA sequencing

...e. Because the DNA fragments are tagged with dyes, they glow when they are struck by laser light to determine the order of one's DNA sequence. Most sequencing today is do...

Female sex hormones play a vital role in defense against sexually transmitted diseases

...d that would prevent herpes virus infection before they could start. Additionally she says, if they were designing a vaccine trial against HSV-2 and if the mice results hold true for women, they could...

Yale Scientists Find MicroRNA Regulates Ras Cancer Gene

...te into the normal structures of the worm ?instead they make an excess of their cells. After identifying let-7 as a cell division regulator, Slack's team used bioinformatics and found the relationship to Ras. Let-7 in humans is identical to the sequence in the worm, and both binding site and pathway for ...

An HIV Protein Plays a Surprising Role in Gene Activation

...tion proceeded as usual in cells lacking TAFs. And they demonstrated that it is Tat—along with its cofactor P-TEFb, which is normally bound to RNA through Tat—that recruits the TAF-deficient TBP. Altogether, these results show a surprising new role for Tat in stimulating assembly of a transcription compl...

Mouse brain tumors mimic those in human genetic disorder

...ypically stop growing after a few years. Moreover, they almostalways occur in children ?these tumors gener...tof microglia helped trigger tumor formation or if they appeared onlyafter the tumor was fully developed. The researchers found that bythree weeks of age, t...

New Clues Add 40,000 Years to Age of Human Species

...first ventured to the Lake Turkana region in 1967, they searched for the earliest remains of pre-human anc...ancestors originated on the African continent, but they differed on when modern humans first evolved, how humans dispersed to populate the globe, and what h...

Spider Venom Could Yield Eco-Friendly Insecticides

...ountered chemicals that behave like spider toxins, they will most likely lack resistance to bioinsecticide...more kinds of venom and uncover insecticide leads, they may be able to target insects that transmit new and emerging human diseases, such as Lyme disease an...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...sive Cancer Center developed the assessment, which they call a functional diffusion map. They used a magne...ation therapy or a combination. Three weeks later, they had another diffusion MRI. After finishing their treatment, the participants underwent standard MRI ...

Gene variations explain drug dose required to control seizures

...ents' drug dosage requirements vary substantially, they added. Rigorous clinical study is required before...armacogenetic approaches can be put into practice, they must be explicitly evaluated for clinical utility in improving patient outcomes, Goldstein said. Th...

Scientists collaborate to assess health of global environment

...o lose the most from environmental change, because they depend heavily on ecosystem services. In some plac...ty and biodiversity by giving them the information they need to make tough decisions. A substantial body of work addressing specific aspects of the assessm...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...r disorder called Pompe disease usually die before they reach the age of two. The researchers also said th...ndered nonfunctional, the researchers demonstrated they could introduce the functioning gene and correct glycogen buildup in heart and skeletal muscle. The ...

Enzyme shown to help protect genomic stability

...Wistar and senior author on the study. "Otherwise, they can recombine with themselves or with other DNA se... attracted increasing attention from scientists as they move beyond sequencing the human genome to trying to better understand how DNA is managed and its ac...

BRCA1 causes ovarian cancer through indirect, biochemical route

...ells. Instead, when the tumor cells were analyzed, they were found to be epithelial cells very similar to those found in human ovarian cancers, with perfectly intact, functioning copies of the BRCA1 gene. "What this says is that the cells that control the menstrual cycle, the ovarian granulosa cells, als...

Needling Chromosomes Reveals Cell Division Secret

...meiosis have to be held together, becauseotherwise they don’t attach to the apparatus called the spindle t...one pole and the other to theopposite pole. But if they are not held together, they attachindependently, and often both sister chromatids can go to the same...

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