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Tag: "they" at biology news

New Technique for Tracking Gene Regulators

...ator proteinsbind to DNA and identifying the genes they regulate just got a stepeasier thanks to a new tec...genes that establish the very identityof cells ?be they brain cells, liver, or blood ?as well as what mightgo awry in certain conditions like cancer. TheBr...

Bound for destruction: Ubiquitination protects against improper Notch signaling

...ized through a process known as endocytosis before they can bedigested by the proteasome, and indeed other types of ubiquitin ligasehave been shown to operate in the endocytosis of ligand-activatedNotch.The group first showed that an increase in nedd4 activity resulted inthe nicked wing phenotype characte...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

...re function" of "channels" in a specific cell type they were studying. Pore function in channels permits t...her patients with similar experiences. To do this, they used the U.S. Food and Drug Administration's voluntary drug side-effect database, the Adverse Event ...

Combination therapy boosts effectiveness of telomere-directed cancer cell death

... the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivid...ision,telomeres get a bit shorter until eventually they become so short thatthe enzymes that copy DNA for cell division no longer work properly andthe cell ...

Inflammatory molecules released by pollen trigger allergies

... A better understanding of these molecules and how they work may eventually lead to new approaches to treating allergies. ...

GATA: a graphic alignment tool for comparative sequence analysis

... the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivid...ision,telomeres get a bit shorter until eventually they become so short thatthe enzymes that copy DNA for cell division no longer work properly andthe cell ...

Research on Worms Yields Clues on Aging

...ays.Further tests on anticonvulsants revealed that they also increased lifespan, with the drug trimethadio...tended their lives, although notto the same degree they extended the lives of worms with no mutations.That indicates the anticonvulsants may affect aging pa...

Imaging Lymph Nodes with Nanoparticles

...in apaper published in this month's PLoS Medicine, they have gone furtherby extending the analysis to patients with different types of cancer,and producing an algorithm that allows semiautomation of the procedure.The authors developed the algorithm in a training group of 36 patientsand then validated it i...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

...rs would become leaders."The key to TDI's success, they argue, is that any discovery would beoff patent. An open-source license would keep all discoveries freelyavailable to researchers and--eventually--manufacturers. The absence ofpatents, and the use of volunteer staff, would contain the costs ofdrug de...

Genome-wide mouse study yields link to human leukemia

...ntifying and getting rid of defective cells before they have a chance to mature and divide. When tumor suppressor genes lose that ability ?as they can if they are silenced through methylation or some other process, it gives cancer a chance to esta...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...ed that iron-starved cellspreserve the little iron they possess by shutting down the major ironusers in or...proteins are substituted in place ofCth2 in yeast, they actually assume its function in yeast cells, saidThiele."Yeast cells illuminate for us what to look ...

Learning to fight an adversary that won't stay down

...nfer resistance to one or more antimicrobials. And they keep coming." However, the mapping of bacterial g...ghtly try to keep these things in reserve for when they are really needed." ...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

... iron very tightly. Bacteria synthesize it so that they can acquire the iron they need to grow ?it is secreted out into the external environment where it scavenges iron and then (wit...

Scientists seek answers on what activates deadly anthrax spores

... array of protein structures, Claiborne said. Once they know the structures, they may not only be able to provide new details on how anthrax develops, but also pick out structural vu...

Found: Missing sequence of the human Y chromosome

...ts report today in the journal GenomeResearch that they have successfully cloned and characterized apreviously intractable DNA sequence: a 554-kilobase-pair genomicsegment near the centromere of the human Y chromosome. This sequencecontains eight putatively active genes that could be implicated insex-asso...

NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis

...e body can fight viral encephalitis. Specifically, they examined how type I interferons--proteins made by ... different stages of the virus' life cycle. First, they inhibit viral RNA and protein synthesis. If this fails, interferons block the virus from forming par...

Live Recombinant Adenovirus Vaccine Technique Explored

...rials may not be ideal in poorer countries because they are expensive and require multiple immunizations. The Hopkins researchers developed their vaccine prototype using canine oral papillomavirus (COPV), which behaves similarly to HPV. Research by other scientists showed that a vaccine consisting of rec...

Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa

...han Emory and the VA Rehabilitation R&D Center they include Rush University Medical Center's Department of Ophthalmology and the Wilmer Eye Institute at Johns Hopkins Medical Center. Retinitis pigmentosa is a pathologic condition that is hereditary and causes progressive retinal degeneration in both ...

The secret lives of whales

...terrupt their lives. Living in a fluid environment they could move to new areas of productivity and find f...he University of Hawaii, studies dead whales after they have sunk to the seafloor. Known as whale falls, their decomposing bodies and skeletons provide an e...

Dinosaur DNA? New Patent Covers Degraded DNA recovery

...team hope to apply this new technology to products they will make available later this year. "We don't plan to turn house cats into saber tooth cats or create a Jurassic Theme Park anytime soon. But we do think this breakthrough has many applications yet to be discovered and we look forward to working wit...

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