A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020
...e replicon particles, referredto as “VRP-neu.?When these non-propagating particles are injected intoan animal, the vector directs the animal’s cells to make thousands ofcopies of the HER2/neu growth protein, says Lachman.In addition, the VRP-neu preferentially homes to specialized immunesystem cells known ...Ants Genetic Engineering Leads To Species Interdependency
...ion oflabor, agriculture, and even slavery.Indeed, these traits have been taken to their extreme in many an...g reliance oninterspecific hybrid workers has left these species unable to surviveindependently of one another.Sara Helms Cahan, Glennis E. Julian, Steven W....Same mutation aided evolution in many fish species, Stanford study finds
...he number of armor plates, Kingsley said. Most of these fish evolved independently from marine ancestors t... a complete set of armor plates. A small number of these fish had one copy of the Eda gene that contained the mutation in question. It's likely that when a ...Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra
...culated that nutrients might play a role. "He had these interesting ideas about foxes and birds and nutrient chains, and I thought we should do some studies to see how robust the idea is," Estes said. The team of researchers, accompanied by a small army of student assistants, conducted extensive surveys ...Researchers trace evolution to relatively simple genetic changes
...w, in countless lakes and streams around the world these low-armored types have evolved over and over again...oast, the East coast, in Iceland, everywhere. When these fish evolve this low-armored state they are using the same genetic mechanism. It's happening over an...Scientists reveal molecular secrets of the malaria parasite
...indicating delayed translation of transcripts from these genes.Hall says that gene-regulation motif "is particularly interestingbecause these proteins, expressed early in the mosquito, are the targetof transmission-blocking vaccines" —that is...Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
...w, in countless lakes and streams around the world these low-armored types have evolved over and over again...oast, the East coast, in Iceland, everywhere. When these fish evolve this low-armored state they are using the same genetic mechanism. It's happening over an...Researchers add new tool to tumor-treatment arsenal
...ge DNA with a drug that sensitizes cancer cells to these agents. The research, led by George Thomas, PhD, ...ical Research in Basel, Switzerland, and completed these studies at UC's Genome Research Institute, where further studies continue. "The use of DNA-damaging...Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers
...ally reduce gas exchange to maintain the oxygen at these safe values," Bradley said. "This hypothesis explains the respiratory pattern of insects in different environments in ways that previous models can't." Two previous models for explaining why insects punctuate their breathing with periods of closure ...Scientists discover unique microbe in California's largest lake
...s onlymade by Acaryochloris and it is what enables these species to useinfrared light."The new microbe is o...his using infrared radiation as well."All three of these organisms are closely related species ofAcaryochloris, but the other two live in the Pacific and mus...Alcohol's effects on gene expression in the central nervous system
... can change gene expression in the brain, and that these changes are likely responsible for many of the 'sy...t was impossible to analyze more than a handful of these genes, however, microarray technology has changed that." Symposium speakers at the June 2004 Resear...Potential Cure for Lymphoma in HIV patients
...ctiveantiretroviral therapy (HAART) to help reduce these opportunisticinfections and improve immunodeficien...vailable and highlysuccessful treatment option for these patients,?said Amrita Krishnan,M.D., a staff physician at the City of Hope Cancer Center and leadaut...Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems
...d IGF-1 during adolescence in normal rats, some of these deficient rats were given growth hormone while the...ed pathologies could be substantially decreased in these animals by inducing a modest deficiency of growth hormone and IGF-1 early in life. However, there is...Research Gives Hope For Liver Damage
...atment of liver scarring. Exciting insights suchas these will inform the design of future therapies."Furthe...t to follow and scientists willexplore the role of these immune-system cells in damage and repair toother organs, including the kidney....New SARS Protein Linked To Important Cell Doorway
... and of pathology and immunology. "Now we can take these viral genetic sequences, which can be attained very rapidly, and get a head start on detailed biophysical investigations of emerging diseases months before we can even begin to work with such diseases in culture." Fremont led the initial analysis, w...Scientists document complex genomic events leading to the birth of new genes
...sulting in deleterious phenotypic consequences. If these duplicated genes acquire new functions, however, t...on to the gene that exhibited the most dramatic of these duplications: RanBP2. RanBP2 is the largest protein found at the nuclear pore complex, helping to re...Nano-Probes Allow an Inside Look at Cell Nuclei
...lors of light when illuminated by a laser. Because these fluorescent probes are stable and nontoxic, they h...ffectiveness of disease-fighting drugs that target these processes. "We could determine whether a drug has arrived where it is supposed to, and if it is hav...DNA Recombination and Repair—A New Twist to RecA Function
...rdinate and organize their activities to carry out these functions has remained obscure. Cox et al. addressed this problem in the test tube, by examining RecA filaments grown from mixing RecA protein with DNA. Previous experiments have shown that filament assembly spreads rapidly in the 5'-to-3' direction...NC State scientist finds soft tissue in T. rex bones
...r and two 65-million-year-old tyrannosaurs. All of these specimens preserved vessels, cell-like structures,...eal exactly what the soft structures isolated from these bones are made of. Do they consist of the original cells, and if so, do the cells still contain gene...Zebrafish may hold key to understanding human nerve cell development
...evelop and whether it may be possibleto regenerate these types of cells in humans one day," said TatjanaPio...os each femalefish produces," she said.By studying these mutant embryos, Piotrowski and her colleaguesdiscovered that during development the zebrafish is "se...