Research advances quest for HIV-1 vaccine
...E10 interacts with and the 3D structure adopted by these amino acids. These study results suggest that 4E10 interacts with gp41 at a conserved region very close to the surface of the virus and they reveal some special characteristics of 4E10 that make it unusually effective at targeting this region. Drs. ...Male circumcision reduces risk of HIV transmission from women to men
...elp define better HIV strategies for prevention in these settings....Another Look Finds Promising Proteomics Test is Not Biologically Plausible
...omics research,?meaning that protocols involved in these investigations should be common across laboratorie...) that could diagnose ovarian cancer across two of these data sets. The M. D. Anderson researchers examined the quality of the data sets and concluded that ...Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering
...y underwriting the design fees required to produce these new arrays,Affymetrix is putting GeneChip technology within reach of virtually anyresearch community," said Lianne McLean, Director, Gene ExpressionMarketing at Affymetrix. "We had great success with this program lastyear. By providing the plant and ......omics research,?meaning that protocols involved in these investigations should be common across laboratorie...) that could diagnose ovarian cancer across two of these data sets. The M. D. Anderson researchers examined the quality of the data sets and concluded that ...Cracking the olfactory code in bees
...omics research,?meaning that protocols involved in these investigations should be common across laboratorie...) that could diagnose ovarian cancer across two of these data sets. The M. D. Anderson researchers examined the quality of the data sets and concluded that ...Signaling protein builds bigger, better bones in mice
...omics research,?meaning that protocols involved in these investigations should be common across laboratorie...) that could diagnose ovarian cancer across two of these data sets. The M. D. Anderson researchers examined the quality of the data sets and concluded that ...Scientists detect probable genetic cause of some Parkinson's disease cases
...ed in the Basque region of Spain and in England.In these new studies, the researchers sought to determine t..., which is proving to be an invaluableresource for these studies," says Diane Murphy, Ph.D., a programdirector at NINDS. "Because the prevalence of this muta...Computers to be used to find blueprint for new influenza drug
...acked. By using advanced software to model the way these atoms behave in highly complex interactions, the atomic structure of a suitable drug can be worked out. Using computer modelling in this way can be of great assistance in drug design. Normally drugs are produced by trial and error in a process that ...Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates
...lls and transplanted into areas of the brain where these neuronshave degenerated in a monkey model of Parki...eurons frommonkey embryonic stem cells and exposed these cells to FGF20, a growthfactor that is produced exclusively in the area of the brain affectedby Park...Ecological destruction fuels emerging diseases
...r, he has found more than 5,000 different types of these often microscopic hangers-on and created one of th...f parasites. And, notably, more than two-thirds of these parasites are new to science. But Dr. Brooks argues that the real work has only just begun. The res...A much-needed shot in the arm for HIV vaccine development
...hat isneeded, they argue, is a way of tying all of these opportunitiestogether, and their plan provides a model for doing just that."A preventive vaccine is the world's best long-term hope for bringingthe HIV/AIDS epidemic under control," said Helene Gayle, Director ofthe Gates Foundation's HIV, TB, and Re...Newly discovered virus linked to childhood lung disorders and Kawasaki disease
...apable of enormously variedpathogenicity." Despite these encouraging preliminary observations, Dr.McIntosh noted that the association between this novel coronavirus andKawasaki disease will require confirmation by others in larger futureinvestigations....Ancient olfaction protein is shared by many bugs, offering new pest control target
...apping sub-populations of neurons, indicating that these proteins participate in sensing particular types of odors. However, one odorant receptor protein, Or83b, is found in almost all olfactory neurons and serves a general function in detecting odors. When the gene for Or83b is deleted, the flies can't sm...Inexpensive, mass-produced genes core of synthetic biology advances at UH
...ing the regulation of genefunction. Down the road, these efforts will improve health care,medicine and the environment at a fundamental level.Using current methods, programmed synthesis of a typical gene coststhousands of dollars. Thus, the prospect of creating the most primitiveof living organisms, which ...Study Links Ebola Outbreaks To Animal Carcasses
...east Gabon and the northwest Republic of Congo. Of these carcasses, 21 gorilla, chimp and duiker carcasses were tested for the Ebola virus, with 14 samples being found positive. In 11 cases, instances of human infection were directly linked to gorilla, chimpanzee and duiker carcasses. To prevent future ou...New Technique for Tracking Gene Regulators
...d greatly speed the process of unraveling the role these proteinsplay in turning on and off the genes that ...ns of thousands genes. Trying toascertain which of these genes CREB regulates by more traditionalmethods, evaluating one gene at a time, would be too labor-i...Bacteria collection sheds light on urinary tract infections
... is resistant to antibiotics. The possibility that these multidrug-resistant bacteria could have an animal origin has major public health implications because of the practice of administering subtherapeutic doses of antibiotics as growth promoters in animals. E.coli is common bacteria found in humans and ...Bound for destruction: Ubiquitination protects against improper Notch signaling
... inthe cytoplasm of treated cells. Taken together, these results suggestedthat Nedd4 works as an antagonist of Notch signaling at an early stage,prior to the proteolytic cleavage of the receptor’s intracellulardomain. Further investigation revealed the specific domain by whichNedd4 interacts with Notch and...HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs
...rotease inhibitors, and the numbers who experience these unexpected side effects are very low -- much less ...ze the availability of protease inhibitors because these drugs are too important for the successful treatment of HIV viral infection and control of AIDS. But...