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Tag: "therapy" at biology news

Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation

...er anti-plaque and anti-inflammation benefits than therapy using the "normal" HDL gene, according to a mouse ...ainst vascular inflammation and plaque. The gene therapy research was supported by grants from the National Institutes of Health, the Eisner Foundation, Ente...

New study calculates millions of years saved in lives of AIDS patients

...ctions (also known as highly active antiretroviral therapy or HAART). To analyze the impact of HAART on patient survival, the investigators used a computer simulation model to examine national surveillance and efficacy data for newly diagnosed adult AIDS patients under care in the United States from 1989 t...

Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer

...most basic laboratory science to the sophisticated therapy being tested today in several tumor types, includi...erapeutic benefit." Eligible candidates for the therapy will have glioblastoma multiforme that has progressed after surgery and radiation therapy, and be ca...

Combination therapy shows promising results in patients with advanced lung cancer

...early phase study pairing an experimental targeted therapy with a common anti-inflammatory produced promising...son Cancer Center reported. Pairing the targeted therapy Tarceva with the anti-inflammatory drug Celebrex increased response rates in lung cancer patients by...

Light-sensitive photoswitches could restore sight to those with macular degeneration

... disease. "I'm convinced that we'll come up with a therapy that will work in the clinic." ...

Clot-busting drug helps revive cardiac arrest patients

...m die. "Clot-busting agents show promise as a new therapy for this abrupt and catastrophic loss of heart fun...ompared to 12 percent of patients who got standard therapy alone. However, not all patients who were revived lived long enough to be discharged from the hospit...

Embryos exposed in 3-D

...use. "Researchers and companies working in cell therapy expressed the need to find better and easier ways ... into the clinic, as part of our goal to make cell therapy safe, routine and simple," Dr. Angelbeck added. Regenerative medicine, which includes cell therapy,...

New technology enables faster, more efficient cell harvest: Cell therapy meeting study

...use. "Researchers and companies working in cell therapy expressed the need to find better and easier ways ... into the clinic, as part of our goal to make cell therapy safe, routine and simple," Dr. Angelbeck added. Regenerative medicine, which includes cell therapy,...

'Smart' genetic therapy helps the body to heal itself

... from rat embryos. "The next step was to try this therapy in patients", said Professor Wirth. "In a first ...ever, the long-term outcome could be both improved therapy to enable a better quality of life for SMA patients, and also the introduction of neonatal screening...

Gardenia fruit compound starting point for diabetes therapy

...dvance, the group added, as no currently available therapy for diabetes actually targets the underlying causes of disease in insulin-producing pancreatic beta cells. Insulin controls blood levels of glucose, the body's main energy source. In those with diabetes, insulin deficiency or insulin resistance cause...

UCLA researchers develop T-cells from human embryonic stem cells

...elop into mature T-cells, raising hopes for a gene therapy to combat AIDS. The study, to be published the we..." Zack said. This in turn could give rise to gene therapy approaches to treat other diseases involving T-cells. In addition to HIV, for instance, the techniqu...

Selectively blocking inflammatory signals may protect mice from MS

...otective approach could be combined with stem cell therapy to repair nerve damage. Several research groups are already studying the use of stem cells to repair damaged myelin sheaths, but in the long term those stem cells would be vulnerable to ongoing immune-mediated damage. But if stem cells could be e...

Statins stop hepatitis C virus from replicating

...(HCV). They could replace ribavirin in combination therapy with interferon. These findings are published in t... with HCV. The standard treatment is a combination therapy of interferon and ribavirin, which is only effective in about 55 percent of patients. The remaining ...

Links between DNA damage and breast cancer studied

...elated death in women. Breast cancer detection and therapy generally target epithelial cells, the primary locus of breast cancers, but in recent years evidence has accumulated that genetic mutations that develop into cancer may occur initially in a deeper layer of breast tissue, called the stroma. Genetic ch...

New research: Soy germ isoflavones reduce bone loss

...en acting as the major cause. Hormone replacement therapy has been the most effective treatment for maintain...ects associated with long-term hormone replacement therapy use. This promising research is another step in advancing soy germ isoflavones as a safe, effective...

A single sugar found responsible for an antibody's ability to treat inflammation

...f times greater than is normally used for antibody therapy for cancer or infection, for example, Ravetch and his colleagues began to look for something that was only present in IVIG in small amounts. That's how they discovered that just the very terminal sialic acid on the Fc portions of the IgG molecule wer...

Gene therapy injected into the brains' of mice with Huntington's disease

...egene Inc., San Diego, have successfully used gene therapy to preserve motor function and stop the anatomic, ...denoassociated viral vector, (AAV) to deliver gene therapy (glial-derived neurotrophic factor (GDNF) directly to the brain cells of mice. GDNF is one of two ...

Adult stem cell research at UB targets damaged hearts

...e long-term, the translation between the MSC-based therapy in the porcine hibernating myocardium and regenerative medicine for humans with chronic coronary artery disease will lead to optimized MSC therapeutics that can be of clinical value in managing aging and curing disease," he said. The research will ...

One therapeutic dose of radiation causes 30 percent spongy bone loss in mice

... has implications for patients receiving radiation therapy and astronauts traveling on long space flights. "We were really surprised at the extent of bone loss," said lead researcher Ted A. Bateman of Clemson University. "We're seeing bone loss at much lower doses of radiation than we expected." The mice s...

Unique dual target specificity of kinase inhibitor key for success against cancer

... of mTOR and p110á represents a safe and effective therapy in the treatment of cancers driven by aberrant signaling through PI3 kinase," says Dr. Weiss. "Glioma represents the most common primary brain tumor, and there are no curative medical therapies. Ultimately, we believe that PI-103 displays the hallmar...

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