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Tag: "therapy" at biology news

Therapeutic role found for carbon monoxide

...our per day, CO gas might be effectively used as a therapy to treat PAH in a clinical setting," says Otterbein, an investigator in the Transplantation Center at BIDMC and Associate Professor of Surgery at Harvard Medical School. Pulmonary arteries ?the blood vessels that carry blood from the heart's right v...

Gene therapy for hereditary lung disease advances

An experimental gene therapy to combat alpha-1 antitrypsin deficiency, a common... in animal models. The next step is to test the therapy with a different version of the adeno-associated virus; about 200 variations of the virus exist in n...

Pilot study successful in taming allergic reactions to food

... a step closer to being able to offer a meaningful therapy for these people.? Egg allergy is one of the mos...n in an effort to build their tolerance to it. The therapy works on a cellular level to alter specific immune system cells, called lymphocytes, that play a par...

Researchers map spread of pathogens in the human body

...y, the debate over the usefulness of multiple-drug therapy must take into account the full evaluation of potential synergistic effects of combining drugs that can target bacteria in different body compartments. Furthermore, drug resistance can be caused, in part, by improper "blanket" use of antibiotics. As ...

New target for cancer therapy identified

A new target for cancer therapy has been identified by Monash University scientists investigating the cell signalling pathways that turn on a gene involved in cancer development. A team led by Associate Professor Jun-Ping Liu, from the Department of Immunology, has identified two ...

Long-term cancer risk follows stem cell transplant recipients

...ablative, allogeneic HSCT is an effective standard therapy for specific life-threatening diseases, such as leukemia or myelodysplastic syndrome, for which blood cell lineages (which originate principally in the bone marrow and circulate in the blood) are abnormal. Destroying the patient's own unhealthy stem ...

Human testis harbors HIV-1 in resident immune cells

...he virus, even though highly active antiretroviral therapy (HAART) can successfully suppress virus in the blo...inuing to rise, the development of anti-retroviral therapy that effectively targets all sources of HIV, including the testis, is gravely needed. The use of thi...

Jefferson scientists find aging gene also protects against prostate cancer development

... forms of treatment such as hormonal therapy. Such therapy focuses on inactivating the androgen receptor by g...tate cancer patients who are resistant to hormonal therapy and showed that SIRT1 blocks receptor activity, halting cancer growth. “We systematically tested eac...

New biologic treatment for tennis elbow may replace surgery for chronic sufferers

...ys. "The results of our pilot study indicate this therapy is as effective as surgery, with sustained and sig...ain). They all had completed a course of physical therapy and had tried some combination of anti-inflammatory medicines, bracing or cortisone shots, all witho...

St. Jude finds clues to hearing loss from chemotherapy

...e-growth with some form of pharmacological or gene therapy intervention," Zuo said....

Development of gene therapy

...sion on Genetic Research, makes it clear that gene therapy already shows signs of success in certain areas, s...search. Moreover, the clinical application of gene therapy requires careful risk/benefit assessment, although in this respect it does not differ substantially ...

Gene therapy study takes aim at prostate cancer

...or College of Medicine (BCM) are hoping a new gene therapy that takes a gene called RTVP-1 directly into the ...eduled, he said. He said the hope is that the gene therapy will reduce the risk that cancer will recur at or near the site of the tumor as well as in distant p...

Cell wall of pneumonia bacteria can cause brain and heart damage

...damage; researchers have also shown how antibiotic therapy can contribute to this damage by increasing the number of cell wall pieces shed by dying bacteria. The team also demonstrated in a mouse model how to prevent this from happening. The study shows that pieces of cell walls from Streptococcus pneumonia...

When nerve cells can't make contact

...en at least the step to experimental diagnosis and therapy in the animal model will be possible." From the point of view of the geneticist, the scientists in Göttingen have the best known animal model for autism worldwide. However, there is a limitation: only very few cases of autism are caused by neurolig...

Killing brain tumors from within: A 'Trojan horse' approach

...t. His previous work has already led to successful therapy in treating leukemia and some lung cancer patients....

Jumping gene could provide non-viral alternative for gene therapy

...lves in DNA. But efficiency comes at a price. Gene therapy trials have been halted because of major complicat... Dr. Kaminski says. In cancer, he suspects gene therapy will focus on this type of modification of normal tissue for protective purposes as well as manipula...

Study shows interruption of antiretroviral therapy increases risk of disease and death

Findings from one of the largest HIV/AIDS therapy studies conducted to date show that a specific strategy of interrupting antiretroviral therapy more than doubles the risk of AIDS or death from any cause. Researchers affiliated with the Mailman ...

Three-in-one virus killer prevents common, often fatal infections

A novel combination therapy drastically reduces the infection rate of three vi...atients who had infections responded to the T-cell therapy and did not require any other treatment," said senior author Dr. Catherine Bollard, assistant profes...

Study of gene transfer for erectile dysfunction shows promise

... researchers. "In the small pilot study, this new therapy was well tolerated and safe," said George Christ, ...ld and 70 percent over age 70 may have ED. The new therapy is a potential alternative to oral medications, such as Viagra, which are not effective for an estim...

Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax

...y 10,000 people were offered 60 days of antibiotic therapy to prevent inhalational anthrax. Adverse events as...ed; therefore, dormant spores that germinate after therapy has been discontinued can cause disease and death. This delayed germination necessitates prolonged u...

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