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Tag: "therapy" at biology news

Malaria treatment efficacy compromised in certain HIV-positive patients

...e examined in an effort to maximize the effects of therapy on both diseases and to decrease the malaria burden in HIV-infected individuals. ...

Novel vaccine shows promise against early-stage breast cancer

...atients with HER-2/neu overexpression were given a therapy of dendritic cells (DC, which work with the B- and T-cells to trigger immune responses) that were treated with HER-2/neu to evoke an immune response. The participants received four weekly vaccinations into normal lymph nodes in their groins and were...

Mayo researchers discover HIV dependence on a human protein

...n be disrupted in the future, it might lead to new therapy for HIV or safer methods of gene therapy. The details appear today in the journal Science. "How an incoming virus co-opts the cell's assistance as it proceeds to establish its permanently integrated state is a fascinating question," says Eric Poesch...

Scientists explore how complex organs develop from a simple bud

...ose salivary glands have been injured by radiation therapy or autoimmune rejection. An investigation into the morphogenesis of the prostate gland and seminal vesicles is included, as well as an in-depth look at the genetic and cellular interactions critical to placental development. Research on this process ...

New study suggests promising drug combinations for sleeping sickness

...flornithine combination has potential as a future therapy for second-stage African trypanosomiasis, and should be evaluated further in clinical trials. ...

'Allergy cells' can aggravate cancer and psoriasis

...it possible for scientists to develop new forms of therapy for the mast cell-related diseases." The group discovered that the CD30 protein, which is found on the surface of the immune systems T-lymphocytes amongst other places, can stimulate mast cells to release proteins that regulate the recruitment of i...

Stem cells found in adult hair follicles may provide alternative to embryonic stem cells

...lead to using a patient's own hair as a source for therapy without the controversy or medical issues of embry...lls. "We see the potential for cell replacement therapy in which patients can be their own donors, which would avoid ethical issues and reduce the possibili...

SARS: No evidence that any of the treatments worked

...LoS Medicine describes a possible new experimental therapy for rheumatoid arthritis and other autoimmune infl... KA, Holmberg J, Holmdahl R (2006) A new arthritis therapy with oxidative burst inducers. PLoS Med 3(9): e348. PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN...

Replacing insulin is top-ranked breakthrough foreseen for health in developing world

... a skin substitute (Apligraf), a bone regenerating therapy (Osteocel) and other medical breakthroughs. An ey...te in India (L.V. Prasad) has used adult stem cell therapy to repair the corneas of over 125 blind patients; an estimated 60% of blindness in poor communities ...

'Trojan Horse' agent halts bone metastasis in mice

...he other half of the mice, but we may have started therapy too late." Rosenblum and his research team then found that VEGF121/rGel dramatically reduced the number of osteoclast cells in the leg bones and further research demonstrated that pre-osteoclast like cells, known as monocytes, had been expressing ...

U-M researchers use nanoparticles to target brain cancer

...needed to survive. The problem with free photofrin therapy is that it can cause damage to healthy tissue. In our study, the nanoparticle becomes a vehicle to deliver the drug directly to the tumor," says study author Brian Ross, Ph.D., professor of radiology at the U-M Medical School and co-director of Molec...

Report calls for improved monoclonal antibodies against solid tumors

...“an equally large number of antibody construct and therapy variables are available for optimization including size, charge, and valence; constant region type and glycosylation pattern; presence or absence of a radioisotope or a toxic moiety; dose, route, and schedule of administration; and use of a tradition...

Molecular 'signature' protects cells from viruses

...ks in 'assembling' the proteins. Importance for therapy The fact that RNAs without a 'signature' stimul...icide opens up completely new perspectives for the therapy of virus infections and cancer cases: for example, RNA chains with a triphosphate end could be produ...

Older men treated for early prostate cancer live longer than those who are not

...months of diagnosis underwent surgery or radiation therapy ?were 31 percent less likely to die than those who... actively treated with either surgery or radiation therapy during the first six months after diagnosis. The remaining group of 12,608 (28.3 percent) were class...

What's next for gene therapy? Plastic

Gene therapy depends upon foreign DNA, even viruses, to deliver genes, therapeutic proteins, or medicine to cells within the body. Many scientists are looking for better chaperones across the cell membrane. Virginia Tech researchers think polymer molecules can b...

Hope for major advance in fighting world killer disease

...'s symptoms have not responded to oral rehydration therapy by three days. The usual tests then take a further three days, by which time the disease may have progressed to a very serious stage. Our project has been to design a rapid method to identify these two types of the disease so that doctors can focus t...

Abnormal overexpression of p53 is a predictive molecular biomarker

...gnosis with treatment of p53 tumor suppressor gene therapy - making it potentially the first predictive bioma...re significantly more likely to respond to Advexin therapy than those whose tumor showed little p53 protein. Advexin is a gene based drug, injected directly in...

Stanford discovery may help predict when toxoplasma can be deadly

... these and other infected people: More aggressive therapy may be warranted if a strain that contains the proteins that increase virulence is the cause of the infection. Humans can become infected by the parasite by accidentally consuming or inhaling the cysts from infected cat feces, by eating meat fro...

Cardiologist's 'living chip' changes science of disease monitoring

...nd could then relay data to physicians, or provide therapy on the spot, in real time? It may sound like sci...face of medical monitoring and, ultimately, device therapy for many types of patients," Rosero said. The company utilizes experts in the fields of molecular ...

Research links 'ecstasy' to survival of key movement-related cells in brain

...hile MDMA itself isn't likely to be an appropriate therapy for neurodegenerative diseases, it may provide insights for developing new drugs that have similar properties. "It's exciting to learn that an abused drug may have potential use for developing new therapeutics," he added. "It really makes you reth...

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(Date:8/29/2014)... Researchers at UC Davis have made some surprising ... infection. Studying simian immunodeficiency virus (SIV), the team ... Paneth cells are early responders to viral invasion ... producing a cytokine called interleukin-1 beta (IL-1β). ... IL-1β causes breakdown of the gut epithelium that ...
(Date:8/29/2014)... Scientists at the Barshop Institute for Longevity and ... the UT Health Science Center at San Antonio, have ... the longest-lived rodent, the naked mole rat. , ... naked mole rats protects and alters the activity of ... proteins. , The factor also protects proteasome function in ...
(Date:8/29/2014)... about what genetic changes transform wild animals into domesticated ... is a University of Montana assistant professor, has made ... of the brain and the nervous system were particularly ... 28 in Science and gives answers to ... ., The domestication of animals and plants, a prerequisite ...
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