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Tag: "therapy" at biology news

Researchers from the University of Navarra analyze new kinds of cancer-fighting antibodies

...s in order to stimulate the immune system. In this therapy the antibodies are directed to the immune system cells in order to provoke a stronger reaction against cancer. This has the advantage of exploiting a mechanism with an action distinct from the other strategies currently being used to treat cancer, an...

UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice

...tiveness. By combining nanotechnology, focused AMF therapy and quantitative molecular imaging techniques, we have developed a safer technique that could join other modalities as a treatment for breast and other cancers." ...

Study shows isolation of stem cells may lead to a treatment for hearing loss

... The team's research is a major step in devising a therapy to reverse permanent hearing loss because it may lead to the activation of cochlear stem cells in the inner ear to regenerate new hair cells. “Clearly we have miles to go before we reach our end goal, but the exciting part is now we can test compoun...

Veterinary scientists explore poultry virus as cancer killer

...g to Subbiah, the use of poultry viruses as cancer therapy poses no threat to humans and several other oncolytic viruses are currently being explored to treat cancer. However, Subbiah’s work is the first to alter Newcastle disease virus through a reverse genetic system to target prostate cancer specifically....

New player in commitment to life as a fat cell

...e (XOR), might therefore offer a novel antiobesity therapy designed to fight fat before it even forms, the researchers said. Known for its role in producing the metabolic byproduct uric acid, XOR had earlier been implicated in gout, said Jeffrey Friedman of The Rockefeller University, senior author of the s...

RNA splicing factor implicated in ovarian tumor cell growth

...on markers, and the other is inadequacy of present therapy for advanced disease. To improve patient survival, it is critical to identify new biomarkers for early detection." Polypyrimidine tract-binding protein is a key regulator of splicing, Beck said. Defects in pre-messenger RNA splicing have been show...

'Marathon mice' elucidate little-known muscle type

.... "These data have potential importance for the therapy of a number of muscular and neuromuscular diseases in humans," Spiegelman's group concluded. "Many conditions accompanied by loss of physical mobility, including paraplegia, prolonged bed rest, and muscular dystrophies, involve a loss of oxidative...

Enhancing activity of marijuana-like chemicals in brain helps treat

.... "This study points to a potentially new kind of therapy for Parkinson's disease," said senior author Robert Malenka, MD, PhD, the Nancy Friend Pritzker Professor in Psychiatry and Behavioral Sciences. "Of course, it is a long, long way to go before this will be tested in humans, but nonetheless, we ha...

Breakthrough vaccine to treat chemo-resistant ovarian cancer

...ced today its plans to launch a new cancer vaccine therapy that expands treatment options for thousands of wo...Cancer Treatment Centers of America. "This vaccine therapy represents a promising new chapter in the fight against this devastating disease and brings hope to ...

A genetic 'gang of 4' drives spread of breast cancer

...hers are exploring clinical testing of combination therapy with the drugs—cetuximab (trade name Erbitux) and celecoxib (Celebrex)—to treat breast cancer metastasis. The research team, led by Howard Hughes Medical Institute investigator Joan Massagué at the Memorial Sloan-Kettering Cancer Center, published ...

New recommendations against a major opportunistic infection -- cryptococcosis

...high fungal load, we recommend starting an initial therapy combining two antifungals, a treatment that is currently only recommended in cases of meningitis and severe pneumonia", concludes Dromer. The authors stress that the three-month mortality rate from cryptococcosis remains 15-20% in Western countrie...

Radiation therapy combo cures prostate cancer long-term

...adiation seed implants and external beam radiation therapy for prostate cancer are cured of their disease 15 ...r who received a course of external beam radiation therapy followed by permanent seed implants a few weeks later. Sixty-five percent of these patients had T2b-...

Robotic therapy helps restore hand use after stroke

A robotic therapy device may help people regain strength and normal ...mproved ability to grasp and release objects after therapy sessions using the Hand-Wrist Assisting Robotic Device (HOWARD). Each patient had at least moderate ...

Antibody therapy prevents type 1 diabetes in mice

...re six months old. Interestingly, the antibody therapy did not appear to cure the NOD mice because the re...rst time, we have demonstrated that CD137 antibody therapy can suppress the development of type 1 diabetes in mice and that the effect is dependent on the indu...

Blame the brain for high blood pressure

...hose patients that fail to respond to conventional therapy for hypertension with drugs that reduce blood vessel inflammation and increase blood flow within the brain. The future challenge will be to understand the type of inflammation within the vessels in the brain, so that we know what drug to use, and how...

UW launches study testing adult stem cells for heart damage repair

... trial is the first human Phase II adult stem cell therapy study in the U.S. Its goal is to investigate the e...pite optimum medical intervention. This type of therapy - regenerative medicine - treats diseases by using growth factors, genes or stem cells to promote bl...

Scientists find new genes for Crohn's disease

... important targets for drug development to improve therapy of Crohn's disease in the future," he said. Stephen P. James, M.D., director of the division of digestive diseases and nutrition at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) agreed, saying that "these important d...

Putting an old drug to a new use

...a big step towards developing it into an effective therapy that can be used on patients," says Martina Muckenthaler, an EMBL alumna who is now at the University of Heidelberg. "Taking nifedipine from bench to bedside could be quicker than for other substances, because it has already been used for years to tr...

Protein discovery targets antibiotic-resistant bacteria

...almonella, she notes, new approaches to antibiotic therapy are needed. The Queen’s findings are published in the on-line edition of the journal Molecular Microbiology. Also on the team, from Biochemistry, are PhD student Jimin Zheng and post-doctoral fellow Vinay Singh; and Microbiology & Immunology M...

UCSF brain tumor vaccine trial shows promising results

...y.?Brem is a developer of the first approved local therapy for glioma. The UCSF clinical trial is a phase1/2 study designed to establish the feasibility, safety and preliminary efficacy of vaccination in patients with recurrent, high-grade glioma. The trial involves two groups of six patients, both of who...

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