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Tag: "therapy" at biology news

Pak1 expression increases tamoxifen resistance in breast cancer patients

...e they were randomly assigned to receive tamoxifen therapy or no treatment. The authors examined whether tum... associated with increased resistance to tamoxifen therapy for women with estrogen receptor positive breast cancer. Patients with ER-positive tumors and low le...

Tumor wizardry wards off attacks from the immune system

...airs T-reg depletion with anti-cancer vaccine as a therapy for pancreatic cancer patients. "We're attacking the problem from different angles hoping to translate these findings to our patients," Linehan says. "Right now, no effective treatment exists for pancreatic cancer." ...

Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection

... anti- CLTA4 or to the Gvax/anti-CTLA4 combination therapy does not deplete the number of Tregs, nor their re...ivity, which suggests that upon completion of this therapy these cells would still be able to control possible adverse immune responses. ...

Finding paves way for better treatment of autoimmune disease

...le Diabetes Research Foundation to see if the cell therapy will work as well in animal models for arthritis a...er levels of regulatory cells. Regulatory T cell therapy also resolved symptoms in a model of graft versus host disease, a problem for some bone marrow trans...

Combined treatment extends life expectancy for lung cancer patients

Combining thermal ablation with radiation therapy extends average life expectancy and decreases recu... of other underlying medical conditions. Radiation therapy has long been used for inoperable lung cancer, and more recently, doctors have used radiofrequency a...

Blood test predicts success of quitting smoking using the nicotine patch

...who may need a higher dose patch or an alternative therapy in order to succeed in quitting," said lead resear...o tailor the type and dose of nicotine replacement therapy for smokers who wish to quit," Lerman said. ...

Gold nanoparticles could improve antisense cancer drugs

...s target the proteins, it is possible through gene therapy to target the genetic material itself before it is ever made into copies of harmful proteins. One way to target the genetic material is to block the messenger RNA by using 'antisense DNA,' which prevents the message from ever becoming a protein." On...

Protein-coated dental implants could improve bone regeneration

...eins ?have already shown promise as a regeneration therapy for craniofacial reconstruction. "None of us had any idea at the time how or if those proteins could be useful in treating tooth loss," Dr. Wikesjö says. To find out, researchers placed the proteins around teeth and implants in animal models. ...

T cells activated to fight HIV basis for dendritic cell therapeutic vaccine

...ntrol but not eliminate HIV infection. If the drug therapy is discontinued, the virus comes roaring back. Dr....rs have hypothesized that this is because the drug therapy does not completely restore CD8 cell immunity to the virus. So, in trying to figure a way to activat...

Novel therapy combinations gain ground in treating hepatitis

...ions. Combination treatment using a new antiviral therapy is showing promise in suppressing the virus, accor... in combination with the frequently used hepatitis therapy pegylated interferon (pegIFN). In this study, researchers evaluated the safety and antiviral respon...

Possible birthplace of malignant brain tumors identified

...nhibition of PDGF signaling could provide a useful therapy for those gliomas in which the pathway is upregulated, especially given the recovery of the normal architecture after regression of the hyperplasia." In a preview of the paper in the same issue of Neuron, Santosh Kesari and Charles D. Stiles wrote ...

Neurons grown from embryonic stem cells restore function in paralyzed rats

...ategy could be tried in humans, Dr. Kerr says. The therapy must first be tested in larger animals to determin...wever, if the future studies go well, this type of therapy might eventually be useful for spinal muscular atrophy, ALS, and other motor neuron diseases. *Desh...

UF scientists restore sight to chickens with blinding disease

...ng gene, known as GC1, and then to develop a viral therapy to treat it. "I will always remember the first an...s this could lead eventually to a vision-restoring therapy for children who suffer from blinding retinal diseases." Like people, chickens possess color vision...

Buckyballs boost antibody's chemotherapy payload

...ful, this could usher in a new class of agents for therapy not only for cancer, but for other diseases as wel...rials solves some intractable problems in targeted therapy and additionally demonstrates the increasing value of the team science approach bridging different d...

NASA technology helping injured US troops

...in Washington, D.C. The revolutionary new physical therapy device named SAM, for the Secure Ambulation Mode, ... regain my mobility. I was able to graduate to the therapy on the parallel bars a lot quicker as a result," said Geddis. "NASA's technology in the walker's ha...

Mass. General study finds potential ovarian cancer stem cells

...ecifically targeted to stem cell as individualized therapy of the future." Donahoe is the Marshall K. Bartlett Professor of Surgery at Harvard Medical School. ...

New genetic test for breast cancer

...h patients can be adequately treated with hormonal therapy alone and which patients will truly benefit if che... If it is less than 11, they will receive hormonal therapy alone. If the recurrence score is between 11 and 25, women will be randomized to receive either horm...

Adult stem cells are touchy-feely, need environmental clues

...hat it might be possible to 'prime' stem cells for therapy in the lab, before implanting them in the heart, spine or whatever damaged environment you want to place them." ...

High estrogen levels associated with dementia in older men

...e large study showed that women receiving estrogen therapy had an increased risk of cognitive impairment and dementia. However, the evidence for how testosterone levels affect men is contradictory. To better understand the role of sex hormones in dementia, researchers led by Mirjam Geerlings, Ph.D. of the...

New approach to vaccine development provides potent, long-lasting immunity

...e understanding of brain function, but also tailor therapy strategies to target slow-learning and increase recovery of muscle control after brain injuries. ...

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(Date:8/1/2014)... is tricky enough. Knowing what causes them at the ... of Iowa researchers have created the most detailed map ... long associated with blinding diseases, such as age-related macular ... in the choroid, which supplies blood and oxygen to ... differences in the abundance of proteins in different areas ...
(Date:8/1/2014)... 2014Biologists at The Scripps Research Institute (TSRI) have identified ... process in brown fat cells. , The study, ... of the Proceedings of the National Academy of ... "brown fat thermogenesis," which is of great interest to ... may also protect against diabetes. , "This finding offers ...
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