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Tag: "therapies" at biology news

Bioartificial kidney under study at MCG

...day, doctors may opt for newer continuous dialysis therapies in which patients with renal failure receive dialysis around the clock. With more standard intermittent therapy, patients get several hours of dialysis three to four times a week. Since kidneys are constantly working, it may seem logical that longer...

A new mechanism of regulating RNA degradation

...take control of gene expression in cells to create therapies to treat disease. While cells have a variety of ways to control gene expression, the trick for players in this game is to recognize them amidst the incredibly complex background of cellular machinery. Now, in a paper in the January 28th issue of Cel...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...take control of gene expression in cells to create therapies to treat disease. While cells have a variety of ways to control gene expression, the trick for players in this game is to recognize them amidst the incredibly complex background of cellular machinery. Now, in a paper in the January 28th issue of Cel...

Researchers discover way to make cells in the eye sensitive to light

...ot a cure for blindness, thefindings could lead to therapies for treating some forms of blindness,such as retinitis pigmentosa. Retinitis pigmentosa is a form ofhereditary blindness where the rods and cones are destroyed, but therest of the eye and retina remains intact. By switching on themelanopsin it could ...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

...ymesystem may be useful in developing preventative therapies against skincancer. Ultraviolet light is a knownsource of damage to our DNA, but under normal conditions humans andother mammals are capable of removing UV-induced DNA damage by a DNArepair mechanism called nucleotide excision repair. Insufficient r...

Neuronal 'traffic jam' marks early Alzheimer's disease

...hese findings to potential diagnostic tests or new therapies remains speculative at this time. "However, if tracers could be developed that would reflect transport function, there could be imaging methods that might be helpful for diagnosis," he said. "And, if these findings continue to hold for humans, the tr...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...ecular control of these genes has implications for therapies that involve tissue regeneration. The researchers...logy may therefore be important for developing new therapies for cancer. Adult resident stem cells have been identified in many types of organs and may be a pot...

Scientists Replicate Hepatitis C Virus in Laboratory

...tential antiviral compounds, which may lead to new therapies for the liver disease that results from infection with HCV. Scientists at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), one of the National Institutes of Health (NIH), conducted the study, which appears in the Feb. 15,...

U-M scientist to talk about tissue engineering at AAAS

...ut the potential for combining seemingly unrelated therapies to improve the benefits of tissue engineering. Fo...ing also can ramp up the effects. "Together these therapies can overcome compromised environments," he said. "Combining therapies can help us overcome some of t...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

...roof-of-concept for using this approach to develop therapies to prevent deadly food allergy reactions as well,?says NIAID Director Anthony S. Fauci, M.D. The injectable treatment puts a brake on the release of a key chemical from cells involved in cat allergy reactions. That chemical, histamine, brings on all...

Mouse brain tumors mimic those in human genetic disorder

..."These findings raise the possibility thattargeted therapies for NF1 brain tumors may involve agents that preventthe supply of growth promoting factors provided by new blood vesselsand microglia."Next, the researchers used the mouse model to investigate a clinicalconcern. Physicians rely on several tests to de...

Gene variations explain drug dose required to control seizures

...ht help determine the optimum dosage of particular therapies for particular patients, Goldstein said. "For most drugs we know a lot about how and where they act in the body," Goldstein said. "The current results support the idea that known drug targets, transporters and drug metabolizing enzymes are good star...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...rials of either the muscle- or liver-targeted gene therapies will likely take several years to launch, Koeberl said. Collaborators on the gene therapy studies include Baodong Sun, Haoyue Zhang, Luis Franco, Andrew Bird, Ayn Schneider, Sarah Young, Y.T. Chen, and Andy Amalfitano, all of Duke Medical Center, an...

Genetically modified natural killer immune cells attack, kill leukemia cells

...that have until now slowed development of NK-based therapies for ALL, according to Dario Campana, M.D., Ph.D., a member of St. Jude Hematology-Oncology and Pathology, and senior author of the Blood report. Progress in adapting NK cells to the treatment of ALL had been significantly hampered because researchers...

Studies reveal methods viruses use to sidestep immune system

...eloping the protease inhibitors and more effective therapies for hepatitis C and possibly other viral infections." A third paper, also appearing in PNAS, describes collaborative research with a group at UT Medical Branch in Galveston. The findings shed light on how HCV disrupts a separate immune pathway in in...

Jumping gene helps explain immune system's abilities

...esto fighting bacterial infections, improving gene therapies and tacklingdisease-carrying insects, Craig notes....are studyingjumping genes as vectors to carry gene therapies and as potentialmodifiers to disrupt the growth-controlling genes of organisms such asmosquitoes and...

UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections

...esto fighting bacterial infections, improving gene therapies and tacklingdisease-carrying insects, Craig notes....are studyingjumping genes as vectors to carry gene therapies and as potentialmodifiers to disrupt the growth-controlling genes of organisms such asmosquitoes and...

New therapy for HIV/AIDS eliminates needles and excessive toxicity

...esto fighting bacterial infections, improving gene therapies and tacklingdisease-carrying insects, Craig notes....are studyingjumping genes as vectors to carry gene therapies and as potentialmodifiers to disrupt the growth-controlling genes of organisms such asmosquitoes and...

Gene sequencing explains bioremediation 'bug'

...esto fighting bacterial infections, improving gene therapies and tacklingdisease-carrying insects, Craig notes....are studyingjumping genes as vectors to carry gene therapies and as potentialmodifiers to disrupt the growth-controlling genes of organisms such asmosquitoes and...

Gene vaccine for Alzheimer's disease shows promising results

... Alzheimer's disease focus on the symptoms sinceno therapies have been clinically proven to slow or prevent progressionof the disease. Amyloid protein deposits are present in the early phaseof the disease - a fact that suggests a gene vaccination would be astep forward in slowing the progression of dementia.Fr...

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