U-M scientist to talk about tissue engineering at AAAS
...researchers at University of Michigan have focused their tissue engineering efforts on the head and neck, i... ways to fill tooth cavities that will not heal on their own, Krebsbach said, and that has led to research in biomaterials, bone and connective tissue functi...Finding Cures For Tropical Diseases: Is Open Source An Answer?
...mpanies can sell enough patented products to cover their R&Dcosts and produce profits for shareholders....overing new drugs for neglected diseases.They call their approach the Tropical Diseases Initiative(www.tropicaldisease.org), or TDI. "We envisage TDI as a de...Cytoplasm affects the number of vertebrae in carp-goldfish clones
...vertebrae. Common carp have 33 to 36 vertebrae in their backbones, while goldfish have 26 to 28. Six of the seven cloned fish had between 26 and 28 vertebrae; one had 31. Although the initial rate of success in producing carp-goldfish clones is low--seven offspring in 501 attempts in this study--the auth...Iron Deficiency Sparks Dramatic Changes In Gene Expression
...of Pharmacology and Cancer Biology at Duke.He said their discovery could aid in the diagnosis and ultimatel...ffects from iron deprivation may gounattributed to their root cause. Other genes affected by ironstarvation are known to be vital in generating energy, copyi...Scientists find missing enzyme for tuberculosis iron scavenging pathway
...en annotated as antibiotic resistance genes due to their sequence similarity to existing antibiotic resistance genes. Dr. Edward N. Baker of the University of Auckland in New Zealand explains, "Generally the sequence of the open reading frame is compared with the sequences of genes for other proteins (most...Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6
...ductcannot be matched by any of our competitors at their respective pricepoints," said Radcliffe. "It also demonstrates our commitment toserving user needs--analysis of protein biomarker data, identifyingchannels that statistically distinguish between different classes andnew import formats were the most f...NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis
...cing pathways to fight the virus' spread. However, their findings showed that interferons fight the virus at different stages of the virus' life cycle. First, they inhibit viral RNA and protein synthesis. If this fails, interferons block the virus from forming particles which can be released and infect oth...Study finds more than one-third of human genome regulated by RNA
...od to define the relationshipbetween microRNAs and their target genes. In December 2003, the samegroup iden...ere no known microRNA targets in anyvertebrate.)In their latest paper, taking advantage of the most recentgenome-sequencing data, the team has compared human...Live Recombinant Adenovirus Vaccine Technique Explored
... to be safe and effective. The researchers believe their process for constructing a replicating live recomb... immunizations. The Hopkins researchers developed their vaccine prototype using canine oral papillomavirus (COPV), which behaves similarly to HPV. Research ......i and Roger Payne of the Ocean Alliance will share their latest discoveries emerging from these high tech v...drial DNA from individual whales. He was amazed at their genetic variation ?an indicator of the past size of their population. Piecing together their ancient...NYU researchers simulate molecular biological clock
...od to define the relationshipbetween microRNAs and their target genes. In December 2003, the samegroup iden...ere no known microRNA targets in anyvertebrate.)In their latest paper, taking advantage of the most recentgenome-sequencing data, the team has compared human...Gene therapy converts dead bone graft to new, living tissue
...uch a transformation can occur because mammals use their skeletons for both support and as a kind of "calci...calcium supplements, so that the body doesn't raid their bones for the calcium it needs. The process works both ways, fortunately, as another set of cells, c...Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey
...ng to Gilmore, “These bacteriaare actively probing their environment for enemies or food. Based onwhether or not they ‘see?other cells, they make the toxinappropriately.?Gilmore says this discovery has several significant implications forthe future. “This is a new mechanism that nature devised to ‘see?thee...Researchers reveal the infectious impact of salmon farms on wild salmon
...d salmon have no choice but to pass by the farm on their seaward migration. The scientists developed new, ... Unlike other species, pink and chum salmon leave their natal rivers while still much smaller than your baby finger ?3 cm long ?and weighing only half a gra...Molecular machine may lead to new drugs to combat human diseases
...rk cycle. When frozen, crystallized introns reveal their structure and the sites at which they bind with va...Group I introns are interesting because they cause their own removal and also splice the ends of the surrounding RNA together, forming a functional gene," Go...Novel Therapy Tested in Mice Could Chase Away Cat Allergies
...ter. These mice became “actively allergic?to cats: their reactions to cat allergen would be comparable to reactions in a cat-allergic person. Scientists injected some of these mice with GFD, and then injected cat allergen into the windpipes of all the mice, including a control group that was not allergic t...Sea skate experiment sheds light on human cell transport
... and other organic material. The researchers made their discovery by using a plant-based substance to bloc...indings exciting." In type 1 diabetes, cells lose their ability to transport glucose. Goldstein and Musch say their findings could explain the problem. Peop...Clam embryo study shows pollutant mixture adversely affects nerve cell development
...ima) withdifferent combinations of BCE and studied their effects on nerve cellgrowth. "On a cellular level,...ps to regulate the cell cycle.They have also moved their studies to a new model system: thezebrafish, a vertebrate with more similarities to humans.Reinisch'...Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
...ctures of the worm ?instead they make an excess of their cells. After identifying let-7 as a cell division...ed. Tissue from lung cancer tumors, compared with their normal adjacent tissue, had reduced let-7 and increased Ras -- the brakes on Ras were removed in lun...Study identifies predictors of HIV drug resistance in patients beginning triple therapy
...ima) withdifferent combinations of BCE and studied their effects on nerve cellgrowth. "On a cellular level,...ps to regulate the cell cycle.They have also moved their studies to a new model system: thezebrafish, a vertebrate with more similarities to humans.Reinisch'...