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Tag: "their" at biology news

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

... of mice missing only the control region for IGF2; their H19 gene was intact. These mice likely mimic the 30 percent of colon cancer patients and 10 percent or so of the human population who have loss of imprinting of IGF2. Only the Princeton mice have been crossed with the APC mice. Both the Princeton an...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...rotection against sexually transmitted infections, their effectiveness is limited because they require part...matched placebo gel. CVL specimens were tested for their ability to prevent HIV and HSV infection of susceptible human cells in culture. Levels of inflammato...

Priming embryonic stem cells to fulfill their promise

...ertissues and organs. However, in order to fulfill their therapeuticpromise, scientists believe that stem c...iche" for a desired type of differentiated cell.In their experiments, the UCSD researchers took advantage of theknowledge that the extracellular matrix in li...

Growth in the sea comes down to a struggle for iron

...hlan at San Francisco State University, along with their graduate students. Several members of the Japanese...y, by the time Wells and his colleagues arrived at their appointed location in the northwestern Pacific, the Japanese team had already injected iron into the...

New, automated tool successfully classifies and relates proteins in unprecedented way

...thin cells, such as simple visualcategorization of their locations."Our tool outperformed clustering based ...imagedata using CD Tagging so that they can refine their approach further.They are also working on ways to "train" a general system that willwork for differe...

New binding target for oncogenic viral protein

...urnal. DNA tumor viruses proliferate by hijacking their host cell's DNA replication machinery. In order to do this, they have evolved mechanisms to override normal cellular replication controls. Simian virus 40 (SV40) accomplishes this task by producing the highly oncogenic large T antigen. This protein c...

Lack of enzyme turns fat cells into fat burners

...rt why the animals can eat more and weigh lessthan their normal counterparts, said Baylor College of Medici...ighcarbohydrate diet without gaining weight, while their normalcounterparts become obese and develop type 2 diabetes."This adds another tissue or organ that ...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

..., they mated females with males, dating the day of their pregnancy, which lasts three weeks. They separated...lf the amount. It had a dramatic effect. At birth, their babies weighed 23 percent less than the control group. After delivery, all babies nursed and all mo...

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

...tion in patients with blockages in the arteries of their legs --a condition called peripheral vascular dis...pain, aching,cramping or fatigue in the muscles of their legs when they walk. Thiscondition also is called " intermittent claudication ".The Emory team, led ...

Fox Chase Cancer Center scientists identify immune-system mutation

...ble to generate mature helper T cells, even though their immature T cells carry the CD4 protein," Kappes explained. "Instead, the mutation redirects them to the killer-cell pathway. "Our new study identifies this defect as a point mutation in the zinc finger transcription factor Th-POK. We show that when ...

Controversial drug shown to act on brain protein to cut alcohol use

... also principal investigatorat the Gallo Center.In their research, the scientists first carried out classic... daily drinking sessions and thendemonstrated that their drinking declined precipitously when theyreceived Ibogaine. The drug was administered either by inje...

Neuronal 'traffic jam' marks early Alzheimer's disease

...an abnormal protein that clogs neurons, leading to their failure and eventual death. The researchers said their findings could provide information that might be used to develop drugs to preserve the molecular tra...

Termites feed through good vibrations

...aboratory experiments have found that termites use their ability to detect vibrations to determine which fo... small blocks and found that the termites switched their preference to the large blocks. Prof Lai created an artificial signal similar to that made by the te...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...aminated with a non-human molecule thatcompromises their potential therapeutic use in human subjects,accord...ficantly reduced, but not completely eliminated.In their experiments, the researchers used recently developed probes todetect the presence of Neu5Gc on the c...

Elusive HIV shape change revealed; Key clue to how virus infects cells

... help pin down how these compounds work and hasten their development into drugs. "The findings also will help us understand why it's so hard to make an HIV vaccine, and will help us start strategizing about new approaches to vaccine development." The studies, performed in the Children's Hospital Boston La...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

... Alzheimer'sdisease have surprised scientists with their ability to recuperateafter the disorder's characte...theseorganelles."Nerve cells move organelles along their branches as a part of theirregular function. Holtzman suspects that this transport breaks down inthe...

Key molecule in plant photo-protection identified

... Alzheimer'sdisease have surprised scientists with their ability to recuperateafter the disorder's characte...theseorganelles."Nerve cells move organelles along their branches as a part of theirregular function. Holtzman suspects that this transport breaks down inthe...

Anti-bacterial additive widespread in U.S. waterways

...tential benefits ofantimicrobial products outweigh their known environmental and humanhealth risks? This is a scientifically complex question consumers,knowingly or unknowingly, answer to everyday in the checkout line ofthe grocery store," said Dr. Halden....

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...n to something new." Epstein and colleagues report their findings in the February 24th issue of Nature. The scientists found that Pax3 plays dual ?and somewhat seemingly contradictory ?roles in adult stem cells: it directs them to become melanocytes, but simultaneously prevents them from differentiating c...

Tiny particles could solve billion-dollar problem

...ickly for a just a few pennies." Hughes, Wong and their collaborators hope to develop a device that would include a cylindrical pump containing a catalytic membrane of the gold-palladium nanoparticles. The device would be placed down existing wells where it would pump water through continuously, breaking ...

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