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A gene's first 'kiss' sets off that affair known as puberty

...t awkward phase when boys and girls are primed for their sexual reproductive years as men and women, appear...essentially wake up the reproductive hormones from their childhood hibernation. Within 30 minutes of kisspeptin being administered to male monkeys, LH, one o...

Chemists create 'Superbowl' molecule; May lead to better health

...en extensively studied and refined by chemists for their wide range of potential uses, including drug deliv...es have much greater capacity and selectivity than their predecessors and show more promise for wider applications." "I wanted a name for our compounds whic...

DNA Molecules Used To Assemble Nanoparticles

...can carry a vast array of molecules on the ends of their arms. It is possible to build a single dendrimer c...orescent protein so that the researchers can track their movement. A series of experiments using cell sorters, 3-D microscopes and other tools verified that...

Bioartificial kidney under study at MCG

...he additional step of having the liquid portion of their filtered blood, called an ultrafiltrate ?which wou...neys require a lot of oxygen and energy to perform their endless task, which makes them easy targets in the ICU, Dr. Szerlip explains. As examples, kidneys c...

Wisconsin scientists grow critical nerve cells

...e therapeutic promise of embryonic stem cells with their ability to replicate indefinitely and develop into any of the 220 different types of cells and tissues in the body. But researchers have struggled to convert blank-slate embryonic stem cells into motor neurons, says Zhang. The goal proved elusive ev...

New push for public health, AIDS spending at African Union summit

...n the African Union spend less than 10 per cent of their annual revenues on health, anti-AIDS and anti-HIV ...oviral (ARV) drugs that inhibit the progression of their disease, which has no known cure. But demand for free drugs vastly outstrips their supply, the cost...

Association of herpesvirus with lung disorder questioned

...is not known. Dr. Katano and colleagues conducted their research using a design similar to that in the ear...ry hypertension. The researchers noted that while their results call the earlier study results into question, there are other possible explanations for the ...

Man and mouse share genome structures

...he right combination of genes to be turned on. In their study, the researchers analyzed the chromatin stru...the co-first author of the paper, Eric Lander, and their Broad Institute colleagues, for the daunting computational analysis required to interpret the result...

Jump-starting T Cells In Skin Cancer

... the tumor such that other T cells can snap out of their stupor and attack the tumor. ...

Molecular biology fills gaps in knowledge of bat evolution

One in five mammals living on Earth is a bat, yet their evolutionary history is largely unknown because of...ecord and conflicting or incomplete theories about their origins and divergence. Now, a research team including University of California, Riverside Biology ...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...nism by which saturated fats and trans fats can do their dirty work," said Spiegelman, who carries out basi...other proteins to turn genes on and off and adjust their activity, like a dimmer switch that varies the brightness of a light. Co-activators join with other ...

A new mechanism of regulating RNA degradation

... "Both Upf1 and Staufen1 can be phosphorylated, so their activities could be regulated by cell signaling pathways, such as those mediated by changes in growth conditions." That would allow the cell to differentially control the level of SMD-target RNAs, while leaving the NMD-regulated RNAs untouched. This...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

... "Both Upf1 and Staufen1 can be phosphorylated, so their activities could be regulated by cell signaling pathways, such as those mediated by changes in growth conditions." That would allow the cell to differentially control the level of SMD-target RNAs, while leaving the NMD-regulated RNAs untouched. This...

Spleen may be source of versatile stem cells

...ntain a population of potentialislet stem cells.In their pursuit of that finding, the MGH researchers inves...tion of Hox11 is radicallyincreased.As reported in their SAGE KE article, the MGH team did find that Hox11was produced in the spleens of adult mice by the sa...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...king new contributions to this field of inquiry in their studies of seafloor hydrothermal fluid discharge into the Earth's oceans, which has been occurring ever since the oceans first formed four billion years ago. Conditions below the sea floor may most closely mimic the environment when life began. "The...

Researchers discover way to make cells in the eye sensitive to light

... mice lackingmelanopsin were exposed to low light, their pupillary response was thesame as normal mice, but when they were exposed to bright light theirpupil constriction was incomplete.The researchers believe that while not a cure for blindness, thefindings could lead to therapies for treating some forms ...

Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants

...ineering Department at UC-Riverside.The results of their collaborative research appeared in an articletitle...bleaching thanconventional fluorescent markers and their small size make them idealfor biological imaging. The researchers then added the molecules togermina...

University of Manchester makes made-to-measure skin and bones a reality using inkjet printers

... tissues and bonesto be grown, simply by inputting their dimensions into a computer. ProfessorBrian Derby,...to tissues, and the lack of penetration alsolimits their size. By using inkjet printing we are able to seed thecells into the construction as we build it, wh...

W.M. Keck Foundation funds study of friendly microbes

...natural metabolic products that they synthesize in their native gut habitats. The W.M. Keck Foundation, established in 1954 by the late W.M. Keck, founder of the Superior Oil Company, focuses its grants on pioneering efforts in the areas of medical research, science and engineering. The grant supports a ...

Yellowstone microbes fueled by hydrogen, according to U. of Colorado study

... on molecular evolution and microbiology,published their report "Hydrogen and bioenergetics in the Yellowstonegeothermal system" this week in the online edition of the Proceedingsof the National Academy of Sciences.The team's findings, based on several years of research at the park,refute the popular idea ...

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