A gene's first 'kiss' sets off that affair known as puberty
Puberty, that awkward phase when boys and girls are primed for t...by a signal literally gets turned on by a molecule that is produced by a gene aptly named KiSS-1. The couple ?a biochemical equivalent to Adam and Eve ?mak...Chemists create 'Superbowl' molecule; May lead to better health
In a development that could one day score a touchdown for better health,...s in Australia have created a "superbowl" molecule that shows promise for precision drug delivery, according to a recent study in the Journal of the America...DNA Molecules Used To Assemble Nanoparticles
... based on dendrimers, star-like synthetic polymers that can carry a vast array of molecules on the ends of...nd of the complex carries a fluorescent protein so that the researchers can track their movement. A series of experiments using cell sorters, 3-D microscop...Bioartificial kidney under study at MCG
... die and over the past 20 years, despite dialysis, that has not changed much." He hopes the new device, d...idneys are constantly working, it may seem logical that longer dialysis is a better option, but, in fact, the issue has not been scientifically analyzed. Th...Viral DNA sequence a possible trigger for breast cancer
... motif to transform cells single-handedly suggests that viral infection may be an important and previously...remained unexplored. Katz and colleagues now show that this sequence is contained in the Env protein of MMTV and show that expression of Env in mouse breas...Wisconsin scientists grow critical nerve cells
...al motor neurons, critical nervous system pathways that relay messages from the brain to the rest of the b...culty making motor neurons, Zhang believes, may be that they are one of the earliest neural structures to emerge in a developing embryo. With the ticking cl...New push for public health, AIDS spending at African Union summit
...n Africans in 2004. "We are definitely optimistic that this time there will be some movement, that this time there will be not just talk about an HIV strategy for the AU but how to tackle an action-o...Association of herpesvirus with lung disorder questioned
...s, now available online. The researchers reported that they were not able to detect human herpesvirus 8 (...e published in The New England Journal of Medicine that reported the presence of the virus in similar samples of lung tissue from a similar number of patien...Man and mouse share genome structures
...detailed large-scale study to date of the proteins that package DNA, researchers have mapped a family of switches that turn genes on and off. Their findings may help scientists understand regulatory mechanisms underlyin...Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
...or to receive radiation. A 15-year follow-up found that radiation therapy was associated with improved bre...ty Health Center in Montreal, and colleagues found that the chemotherapy and radiation regimen, compared with chemotherapy alone, was associated with improv...Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
...or to receive radiation. A 15-year follow-up found that radiation therapy was associated with improved bre...ty Health Center in Montreal, and colleagues found that the chemotherapy and radiation regimen, compared with chemotherapy alone, was associated with improv...Jump-starting T Cells In Skin Cancer
... 17 issue of the Journal of Experimental Medicine, that these vaccines work by increasing the number of immune cells called killer T cells that can attack the tumor. In an unexpected finding, however, they discovered that that these cells mostl...Molecular biology fills gaps in knowledge of bat evolution
... paper in the Jan. 28 issue of the journal Science that uses molecular biology and the fossil data to fill... also quantifies the fraction of the fossil record that is missing for bats." The team, using DNA sequencing, analyzed data from portions of 17 nuclear gen...Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
...have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods ...l, scientists led by Bruce Spiegelman, PhD, report that the harmful effects of saturated and trans fats are set in motion by a biochemical switch, or co-act...A new mechanism of regulating RNA degradation
At first, we thought that gene expression was modulated only by transcription factors. Then we found that the RNA resulting from transcription could be regulated by the RISC complex (siRNA-mediated degradat...FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
At first, we thought that gene expression was modulated only by transcription factors. Then we found that the RNA resulting from transcription could be regulated by the RISC complex (siRNA-mediated degradat...Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer
...he integrity of the genome. Studies have suggested that deficiency in cells' capacity for DNA repair contr...repair capacity in the nucleotide excision pathway that fixes DNA alterations known as bulky DNA adducts is associated with breast cancer risk, Regina M. Sa...Spleen may be source of versatile stem cells
...etts General Hospital (MGH) researchers discovered that the spleen might be a source of adult stem cells that could regenerate the insulin-producing islets of thepancreas. In a follow-up to that unexpected find...Genes In The Interferon System Important In Systemic Lupus Erythematosus
...l," says Professor LarsRönnblom. "Itis remarkable that by studying only eleven of the some 200 genes that...ces were virtually the only researcherswho claimed that the interferon system, which is involved in the body'sdefense against viruses, etc., was also behind...UCSB scientists probe sea floor venting to gain understanding of early life on Earth
...ion, a major funder of this work. The NSF explains that subseafloor ecosystems may represent both the crad...r J. Ehrhardt –?studied "abyssal" underwater hills that cover a large geomorphic terrain on the ocean floor and are the most common landforms on the Earth. ...