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Tag: "tested" at biology news

Firefly protein lets researchers monitor molecule linked to cancer

...eal time." In their study, Gross and Piwnica-Worms tested the technique in live mice by transplanting genetically altered tumor cells and by using a technique that inserted the fused IKB/luciferase protein into liver cells only. They are currently working to develop a line of mice with the IKB/luciferase fu...

Researchers develop new testing methods for potential monkeypox or smallpox outbreak

...for diagnosis. In comparison, OHSU's research team tested samples using a variety of methods. One such test, called the ELISA test, resulted in very accurate results (95 percent sensitivity, 90 percent specificity.) This high level of accuracy allowed Slifka and colleagues to correctly diagnose previously c...

New results validating Pall prion reduction filter disclosed at ISBT Congress

...ogy of the New York University School of Medicine, tested the filter against sporadic CJD. Sporadic CJD is t...ugh infected blood. In the U.S., a second cow just tested positive for BSE. "Considering the lengthy, asymptomatic incubation period of vCJD in people, no on...

Old drug shows new promise for Huntington's Disease

...rst part of his study, Massa and his research team tested the effect of Clioquinol on neurons in cell culture that contained a form of the mutant Huntington's gene. "We found that not only did cells look better and survive a bit longer when exposed to the drug, but they also seemed to make less of the toxic...

Researchers find ways to turn manure into power

...compost pile that came from the paved pens will be tested further in a small-scale combustion testing project in College Station. These test results will focus on using pulverized manure samples as reburn fuel in a secondary combustion chamber to lower the nitrogen oxides and specific metal emissions from ...

Techniques available to detect soil that inhibits destructive soybean pest

...an cyst nematode damage, so soil and roots must be tested to reveal or confirm the pests' presence. Infestation gradually causes progressively lower yields and the worst cases result in yellow and stunted soybean plants. Plants with severe, visible damage can occur in patches in highly infested fields. The...

Fighting malaria by manipulating mosquitoes' sense of smell

...nts that have passed all these tests will be field tested in cooperating villages near Ifakara and in The Gambia under the supervision of IHDRC and MRC Laboratories' researchers. "By combining laboratory-based and field-based studies, we expect to establish an effective strategy for developing extremely po...

Vaginal gel may provide a new approach to HIV prevention

...SIV, which infects only monkeys. The Tulane team tested gels containing two small molecules and a peptide ... were each effective when used alone and also when tested in combination. Of 20 monkeys given the BMS and Merck microbicides in combination, 16 were protecte...

U-M scientists discover identifying markers for primitive blood-forming stem cells

...matopoietic stem cells. In a third step, the team tested another SLAM marker called CD48, and found it to be expressed only on more advanced cells. It was not present on either HSCs or progenitor cells. "Each marker is expressed at a different stage of the hematopoiesis hierarchy," Morrison says. "Selecti...

Color perception is not in the eye of the beholder: It's in the brain

... "Those early experiments showed that everyone we tested has the same color experience despite this really profound difference in the front-end of their visual system," says Hofer. "That points to some kind of normalization or auto-calibration mechanism--some kind of circuit in the brain that balances the ...

Female butterflies go for sparkle -- not size -- when choosing to mate

...ying traits of different size and color. They then tested female preference for wing size, eyespot size, quantity of eyespots on the wing, eyespot and pupil color, and pupil reflectivity. "Once we found a trait that appeared to be important, we then would exaggerate it or reduce it to pin it down," said Mo...

Volunteers sought for avian flu vaccine study

... various other medical centers around the country, tested the vaccine in normal, healthy adults and determined it was safe to test in other populations. The development of a widespread epidemic of avian influenza, or "birdflu," is of growing concern throughout the world. Human cases, with a high fatality...

Complex gene interactions account for autism risk

...and 204 included one autistic individual. The team tested for associations between particular gene variants and the disease. They also applied sophisticated statistical methods designed to zero in on the effects of particular gene combinations. The researchers found that one of the GABA receptor genes, GAB...

Modifications render carbon nanotubes nontoxic

...ed 50 percent for these compounds, which were each tested to a level of 2,000 parts per million. Just as with buckyballs, CBEN found that higher degrees of surface modification led to lower toxicity for SWNTs. "We now have two studies on carbon nanoparticles that show us how to make them dramatically less ...

New antibody shows promise as cure for anthrax

... the SFBR Department of Comparative Medicine, have tested the re-engineered antibody with guinea pigs to determine if the antitoxin could protect against a true infection with anthrax spores. "We expected the antitoxin to extend the lifespan of the infected animals," says Patterson, "but since we did not c...

Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy

... for whole-body gene delivery. In this study, they tested AAV-8 in an animal model of human muscular dystrophy called limb girdle muscular dystrophy, or LGMD. In human LGMD, defects in a muscle cell membrane protein known as delta-sarcoglycan lead to severe damage and weakness to muscles, particularly aroun...

Agricultural workers at increased risk for infection with animal flu viruses

...ith no occupational pig exposure. The researchers tested the serum samples for antibodies to several then-current swine and human influenza A viruses. The results showed that all three occupational study groups had markedly elevated antibodies to swine flu viruses compared with the control group. Farmers ...

A bug's life: Exceptional genomic stability yet rapid protein evolution in a carpenter ant mutualist

...s. Another important feature of B. pennsylvanicus tested by the researchers was the rate of protein evolution, as measured by amino acid changes, since the divergence of B. pennsylvanicus from their free-living ancestors. The researchers showed that the amino acid sequences of Blochmannia have diverged app...

Living anti-HIV gel shows early promise

...l have to be successful before the bacteria can be tested in people. "It is a fascinating concept," says Harold Kessler, associate director of the Infectious Diseases Section at Rush University Medical Center in Chicago, United States. "Obviously there is a great deal of work ahead, but it is certainly a no...

Cornell finds natural selection in humans

...ntify novel amino acid variants that could then be tested for association with human disease in subsequent studies. The Cornell researchers became involved at the analysis stage in order to make predictions about what types of changes are most likely to be functionally important. ...

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