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Tag: "tested" at biology news

Designing vaccines by computer

...finds something promising it can be experimentally tested to see if it will trigger a response. Dr Darren Flower, an international leader in this work, said, "A crucial feature of this search strategy is that we don't have to know what a foreign protein actually does in order to identify it as having fragm...

Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics

...developing a technique where the molecule could be tested in an electrolyte solution, a condition that past ...o exhibit the predicted electrical properties when tested without a conducting solution. Physicists attempting these measurements avoided using electrolyte so...

Science study holds implications for gene therapy and stem cell biology

...s. To date, disabled retroviruses have mostly been tested experimentally in laboratory settings but are also being tested in well-controlled clinical trials to treat severe inborn diseases or cancer in humans. Retrovirus-...

AIDS Public Awareness Campaign Expands Following Report Of Rapidly Progressive HIV

...HIV in the nation. "No one should be afraid to get tested for HIV," Dr. Novello said. "Remember, this virus ...you at risk for HIV." Individuals who wish to get tested may choose to do so anonymously or confidentially. With anonymous testing, a person does not provide...

Gov't Creates Gene Database of Normal Human Tissues

...enes have been printed in tiny spots. Cells can be tested by manipulating them so that genes activated in the cell will match up with the known gene samples, like two pieces of Velcro attaching to each other. The cellular genes are treated with fluorescence and literally light up the gene dots on the chip. ...

Innovative coating could give medical implants a longer life

...cientific society. While the coating has not been tested in humans, it holds promise for use on a variety o... an immune response in the body." The researchers tested their coating on titanium dioxide (a material common in medical implants) in environments that simul...

Researchers pioneer new gene therapy technique using natural repair process

...rred at the break site and 11 percent of the cells tested had traded one copy of the mutant gene for the correct version. In addition, 6 percent to 7 percent of cells had traded both copies of the bad gene for the correct version. With the correct IL-2R gene in place, levels of the IL-2R protein also were ...

Asymptomatic HIV babies could use earlier treatment

...gns of infection in the newborns of women who have tested positive for HIV. The study was supported by funding from the Office of AIDS at the California Department of Health Services. Researchers from 10 institutions participated in the study, including Maldonado and three others from Stanford’s Department...

Mice brains shrink during winter, impairing some learning and memory

... 13 weeks. Their spatial learning and memory were tested using a water maze test in which the mice had to s... just below the surface of opaque water. They were tested for several days to determine how long it would take them to find the platform, and whether they rem...

Life detection instrument passes key test on road to Mars

... their experiments and, with six other colleagues, tested the integrated subcritical water extractor together with the MOA on samples from popular test sites such as the "Rock Garden" and the "Soil Pit." One thing they learned is that with low environmental levels of organic compounds, as is likely to be t...

Major new UNC-based drinking water study suggests pregnancy fears may be overstated

...gineering. The scientists selected and repeatedly tested three properly functioning water purification facilities, including one with moderate levels of chlorinated disinfection byproducts, one with moderate levels of brominated disinfection byproducts and one with low levels of all disinfection byproducts...

U of T researchers map role of Epstein-Barr virus in cancer

...e Structural Genomics Consortium. The researchers tested the effects of EBNA1 on human cells grown in culture. Frappier says the paper provides a structural explanation of this protein complex so scientists can see in molecular detail how the EBNA1 protein binds to USP7 and the resulting impact on cell gro...

Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine

...y be harmful. Schneewind and colleagues, however, tested 11 truncated versions of LcrV, snipping out, from different locales, 30 of the protein's 326 amino acids in hopes of eliminating the elements that suppressed the immune response but retaining enough of the normal protein's structure to generate prote...

Random gene expression may drive HIV into hiding

...oduction. This intriguing notion still needs to be tested experimentally, and more broadly, much work remains to be done to understand the functional role that gene expression noise potentially plays in the progression of disease." ...

Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT

... skin and prostate. The compound, tricirbine, was tested at various cancer centers from 1982 to 1996 and found to inhibit some cancers, but researchers failed to determine why. The Moffitt-USF team discovered that tricirbine works only against tumors in which the cancer-causing Akt protein is abundant and/...

MIT engineers an anti-cancer smart bomb

...ere it slowly releases the chemotherapy. The team tested this model in mice. The double-loaded nanocell shrank the tumor, stopped angiogenesis and avoided systemic toxicity much better than other treatment and delivery variations. But it is patient survival and quality of life that really inspire this res...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...t fusion protein was administered orally, and when tested in mice, increased the white blood cell count for three days, whereas the injectable agents only maintain effectiveness for one day," Shen says. "We have finally produced an orally-administered protein with a desirable therapeutic activity. This tech...

Improved statistical tools reveal many linked loci

... distinguish whether one or both of the loci being tested are responsible for altered expression levels. This problem grows exponentially with each added test site. This approach also failed to reveal that hierarchical relationships between two genomic locations control about one in seven yeast expression t...

Scientists inhibit cancer gene

...er DGKs we have tested. This time, though, when we tested mice with an activated Ras gene, but an absent DGK iota gene, the number of tumors was significantly reduced," Topham says. "This result is interesting, because it happened when the Ras gene was activated. The implication is that a drug therapy could...

Researchers develop promising new gene network analysis method

...tems and a professor at the Università di Bologna, tested two methods to try to model this network. One was the linear Markov model, a decades-old tool used to crunch everything from sports statistics to language production. The other was a correlation method based on network theory, which has been used to...

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