New drug shows promise as powerful anticancer agent
...tive and, in many cases, strongly synergistic when tested in combination with other chemotherapeutic agents. Studies examining normal human cells show that, in contrast to tumor cells, they are not influenced by ON01910. The authors suggest that because ON01910 is highly effective in combination with other...Nanoparticles offer new hope for detection and treatment
...rticles in diagnosis and therapy in humans will be tested in clinical trials in about one and a half to two years. The spherical nanoparticles are a few thousand times smaller than the dot above this "i," yet each can carry about 100,000 molecules of the metal used to provide contrast in MRI images. This c...Anti cancer virotherapy well tolerated in first human administration, research finds
...mited (ASX:PSX). Professor Shafren has previously tested this virotherapy on cancer tumours in mice and this is the first testing in humans. Two patients only were approved to receive this virotherapy. Professor Shafren reported to the conference that this research team had injected a single dose of Coxsa...Nano-bumps could help repair clogged blood vessels
...g as much dangerous scar tissue." The researchers tested discs of titanium containing surface bumps about as wide as 100 nanometers ?or billionths of a meter. The metals used to make conventional stents have features about 10 times larger or none at all. The nanometer-scale bumps mimic surface features of ...Used in a new way, RNA interference permanently silences key breast cancer gene
...reast cells transduced with STAT3, shRNA were then tested in immunocompetent mice, researchers found that the treated breast cancer cells were unable to form breast tumors either at the site of injection or at distant sites typically involved in metastatic breast cancer in this mouse model. Arlinghaus poin...Study: 'homemade' gene expression technology unreliable
...can quickly pinpoint genes affected by drugs being tested to treat heart disease, mental illness, infectious diseases and cancer. In the past, researchers were only able to analyze a few genes at once, and they were often uncertain whether these were of greatest importance. Spencer's group is using the tec...Duke engineers develop new 3-D cardiac imaging probe
... new 3-D model. The casing design already has been tested and approved for use. The new Duke 3-D probe is tipped with a dime-sized array of 504 individual ultrasound sensors. Each sensor is as wide as a few human hairs. "It took a craftsman to create this probe," said Smith. "Not many graduate students cou...Grasping metaphors: UC San Diego research ties brain area to figures of speech
... understand metaphor. Ramachandran and colleagues tested four right-handed patients with damage to the left... of symptoms, got all 20 of the 20 proverbs he was tested on wrong. Prodded on "all that glitters is not gold," he finally said that it meant you had to be ve...Turning viruses into allies against cancer
...ant to thwart the spread of cancer cells, is being tested in patients with a variety of tumor types, includi...s. In a phase I/II clinical trial, the scientists tested their modified virus in 26 patients, including eight with melanoma, 13 with breast, three with head ...The evolutionary triumph of flower power
...st Haviland-Jones had conducted three studies that tested the ability of flowers to induce positive emotion....nal niche model. In the first study, flowers were tested against other gift stimuli, such as a fruit and sweets basket and a large decorative candle. Of the ...Researchers find promising cancer-fighting power of synthetic cell-signaling molecule
...is is what suggested to us that Enigmols should be tested against other cancer types," Merrill explained. S... investigators speculate. Enigmols are also being tested in combination with other cancer chemotherapeutic drugs using funds from EmTech Bio -- a life scienc...Double triumph in stem cell quest
...s were male. However, Verlinsky's team has not yet tested the HLA proteins on the cell surface to prove that the stembrids are an immune match for the adult donors. By contrast, Hwang's team has shown that the ESCs derived via therapeutic cloning have the surface markers that make them compatible with the d...Roots Engage in Underground Chemical Warfare
...ts, however, root exudates did not kill all of the tested strains of bacteria. One particular strain of Pseudomonas syringae, a bacterium that causes disease in both tomatoes and Arabidopsis, has a seemingly fail-safe mechanism to overcome the plant's defenses. The bacterium not only survives exposure to th...Measuring hormone cuts antibiotic use in half in pneumonia patients
...rd antibiotic treatment, while the other was first tested for procalcitonin levels. Fifteen percent of those patients had very low procalcitonin levels, and were presumed to have viral pneumonia; they were not given antibiotics. The remaining 85% had high levels and were started on antibiotics. The research...NIAID begins clinical trial of West Nile virus vaccine
...Center in Bethesda, MD. The vaccine, which will be tested first in 15 healthy adult volunteers, was develope... Vical Inc., San Diego, based on an animal vaccine tested at the Centers for Disease Control and Prevention (CDC). Vical also manufactures the experimental va...Friendly bacteria in humans may protect against HIV
...l and vaginal lactobacilli from healthy humans and tested the ability of different strains to bind to baker's yeast, another microorganism coated with mannose-rich sugars. They found a small group of lactobacilli that bound to mannose and further testing against HIV revealed two strains that specifically tr...Road salt affects mitigation wetlands
...y of about 28 parts per thousand. Silver has also tested all six wetlands for salinity and looked in bottom sediment for non-biting midge populations because midges are good indicators of stress. "Last year all the wetlands went back to zero salinity in mid spring," says Silver. "We are not sure if this w...The lopsided brain: Attention bias is shared by humans and birds
...d why this might be. In the new work, researchers tested two bird species, the domestic chick and the pigeon, for their performance on a task in which they were allowed to freely peck at grains of food that were spread evenly in an area before them. Though the birds' bodies were positioned at the midline o...Secret of smallpox's success may lead to bioterror cure
...he effectiveness of the vaccine cannot actually be tested through clinical trials on humans. Instead, the vaccine is tested on mice and other animal models, using viruses closely related to smallpox that are lethal to those ......and analyzing water samples twice each month. They tested the samples for concentrations of phosphorus, nitrates and several other chemicals. The researchers also gathered data on water flowing into the wetland from rain and snowfall and from ground sources. They wanted to know if the design of this experi...