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Tag: "tested" at biology news

Kinovate Life Sciences Launches Nittophase?High Performance Solid Support For Oligonucleatide Synthesis

... oligonucleotides. NittoPhase?has been rigorously tested at both small and large scales, and has been observed to exhibit superior characteristics and performance when compared to other solid supports currently on the market. NittoPhase?has great potential to decrease manufacturing costs due to it’s signif...

Chemists identify key gene in development of type 1 diabetes

...they add. Besides prevention, ISO-1 also is being tested in animals to determine whether it will help in the actual treatment of ongoing type 1 diabetes and type 2 diabetes, the more common type. Results are not yet available from these tests, the researchers say. Although nobody knows the exact cause of ...

Vascular structure and function improve with diet and exercise

...he brachial (arm) and carotid (neck) arteries were tested for intima-media thickness and arterial distensibility. Both reflect the health of the blood vessels. The thicker and less distensible (elastic) the arteries are, the greater the load on the heart. This often results from changes in blood pressure, b...

Towards precise classification of cancers based on robust gene functional expression profiles

...they add. Besides prevention, ISO-1 also is being tested in animals to determine whether it will help in the actual treatment of ongoing type 1 diabetes and type 2 diabetes, the more common type. Results are not yet available from these tests, the researchers say. Although nobody knows the exact cause of ...

New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines

...bodies have not been made in response to currently tested HIV vaccines," said Barton Haynes, M.D., lead author of the study and director of the Human Vaccine Institute at Duke University Medical Center. The researchers will report their findings in a forthcoming issue of Science. The results were published...

Antibiotic might fight HIV-induced neurological problems

...imer's disease, stroke and more. The drug is being tested in early clinical trials for some non-HIV-related conditions. "Last year we discovered that SIV triggers some of the same biological pathways of cell death and inflammation as these other diseases," says Sheila Barber, Ph.D., assistant professor of ...

Rats infected as newborns grew up vulnerable to memory problems during an immune challenge

.... Once the pups grew up, Bilbo and her colleagues tested the adults' memory about 60 days after birth. To t...okines called interleukins than control pups (they tested 32 PUPS in all). Immune cells release these cytokines, or certain protein molecules, in response to ...

Effective Cancer Treatments Follow The Clock

... times than did normal mice. The researchers then tested whether this effect might be due to differences in the metabolic activation of the anti-cancer drug, but found essentially none. “This was a real surprise, because some of the enzymes involved in activating CY in the liver show circadian rhythms,?sai...

Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy

... results of several other adjuvants that have been tested in other trials. By comparing single variables in parallel we believe we can develop effective cancer vaccines in a much shorter time than the conventional approach of trying variables sequentially." The CVC has clinical research sites in Australia, ...

Wisconsin researchers identify sleep gene

...d not flow through it. When the researchers first tested flies with the Shaker gene, they found that some of them with other mutations were normal sleepers. But these flies became short sleepers when the researchers removed genetic modifiers from their genome. "This told us that genetic forces push hard a...

Norovirus, AIDS vaccine and Hepatitis Virus

...cted from 34 patients with traveler's diarrhea and tested for the presence of norovirus. The virus was detec...a new class of interferons, interferon lambda, was tested for its ability to inhibit HBV and HCV replication. Results showed 90% inhibition of HBV after twent...

Researchers devise way to mass-produce embryonic stem cells

... differentiate without prompting. Yang and Ouyang tested both sets of cells ?the ones grown in a flask and ...ioreactor experiment, 94 percent of the stem cells tested positive for these proteins, compared to about 85 percent of the cells grown in the flask. The rese...

Substance protects resilient staph bacteria

...ys all 74 strains of S. epidermidis that his group tested also produced PGA, as did six other genetically related Staphylococcus pathogens. "This could be very important to vaccine development because the PGA is present in every strain of the organism," Dr. Otto says. "If a vaccine can be developed to negat...

HIV vaccine trial breaks ground for future research

...develop a vaccine for hepatitis B. The vaccine was tested in a double-blind, randomized study of healthy par...ssed for risk. At each visit the participants were tested for HIV infection, and for those who were positive, HIV-1 plasma RNA load and CD4 cell counts were m...

Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert

...epartment of Biological Sciences. "Every sample we tested had bacteria in it." Minkley is conducting analyses to determine the genetic characteristics of the recovered bacteria to identify the different microbial species present in the samples. He also is testing the bacteria's sensitivity to ultraviolet (...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...> The PK/PD approach aims to ensure that doses tested in clinical trials are adequate and likely to yield good results, said Dr. William Craig, a professor of medicine at the University of Wisconsin, adding that until now, “many, many antibiotics that initially came out have either had their dosages cha...

Light therapy may combat fungal infections, new evidence suggests

... costs that fungi present." The researchers first tested the importance of genes with known roles in light sensitivity of another, distantly related fungus. Yeast strains lacking one of those genes, known as white collar 1 (BWC1), mated equally well in the light or the dark, implicating that gene in the fu...

Gene therapy promising for growing tooth-supporting bone

...rk will need to be done before the approach can be tested in humans, Giannobile added. He said he optimistically would like to see initial trials begin in humans in four to seven years. BMP-7 is part of a family of proteins that regulates cartilage and bone formation. Recent studies have shown that BMPs ar...

Computational Method Speeds Mapping of Cell Signaling Networks

...thways," according to team member Dana Pe'er. They tested their technique--a combined approach of state-of-the-art experimental and computational methods that "fit like a hand in a glove,"--by mapping a well-studied signaling network in human immune system T-cells. This feat originally took researchers deca...

Promising new West Nile therapy cures disease in mice

...ully fend off the West Nile virus. The researchers tested their antibody in mice and say its success warrants further development and testing in people with West Nile disease. "West Nile virus has emerged in the United States as a regular seasonal threat, particularly for people over 50. We currently do no...

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