Grabbing addiction by the tail
...hese results in cell cultures, Wang and colleagues tested the peptide in rats that had been given amphetamine once every other day for 20 days. During this period, the animals displayed stereotypical behavior such as repeated sniffing, licking, and grooming, indicating a craving for the drug. Such behavior ......nto distinct circuits. But Callaway and Yoshimura tested the prevailing notion of columnar function by devising an experimental method that used glass microelectrodes to "listen" to two neurons at a time. They used rats, whose brain organization mirrors that of a human, and dissected tiny vertical slices t...Past illegal blood donation in China linked to hepatitis C virus infection
...questionnaires were administered and blood samples tested for HCV antibodies. HCV rates were 8% in all participants, 28% in former plasma/blood donors, and about 3% in non-donors. Selling blood or plasma was the strongest independent predictor for HCV-positive findings. Receiving a blood transfusion was als...Retinal scans eyed for New Mexico show cattle
...rst-of-its kind project for New Mexico, scientists tested 35 market steers from 18 Quay County farm families, using a combination of eye-scanning and radio frequency identification (RFID) ear tags for animal ID evaluation. Most of the cattle were high-value 4-H and FFA show cattle that spent much of the pas...Extinct giant deer's descendant found in UK
...ish Elk (giant deer) lives on our shores. The team tested for DNA and skeletal features to prove that the gi... axis deer, the hog deer and fallow deer) were DNA tested and their characteristics - such as antlers, skull and teeth size & shape - were studied. Two gi...Study Holds Promise For New Way To Fight HIV
...ish Elk (giant deer) lives on our shores. The team tested for DNA and skeletal features to prove that the gi... axis deer, the hog deer and fallow deer) were DNA tested and their characteristics - such as antlers, skull and teeth size & shape - were studied. Two gi...Embryonic stem cells accrue genetic changes
...l's mitochondria. "The majority of the lines we tested had genetic changes over time," says Chakravarti. "Whenever you have something in a culture dish, it can change, and it will be important to identify, keep track of and understand these changes." At this point, the precise effects of these changes ...Restoring silenced suppressor gene kills lung-cancer cells
...," Huebner says. "Experimental drugs are now being tested that cause demethylation and may reactivate WWOX and other genes." For this study, Huebner and her colleagues used three different lines of laboratory-grown lung-cancer cells that were missing WWOX protein. The researchers then used a virus enginee...Reducing antibiotic use lowers rates of drug-resistant bacteria
...more difficult to control. Researchers in France tested two intervention methods intended to reduce the rate of carriage of penicillin-resistant pneumococci in kindergarteners. The prescription-reduction method involved not prescribing antibiotics for respiratory tract infections that were thought to be v...Natural compound from 'pond scum' shows potential activity against Alzheimer's
... it could be many years before the new compound is tested as a drug candidate in humans, the scientists caution. In addition to Gademann, others involved in this study include Friedrich Jüttner and Paul Becher of the University of Zürich and Julien Beuchat, currently with the Université de Lausanne in Switz...Anti-cancer drugs may hold promise for premature aging disorder
...erase inhibitors (FTIs), which are currently being tested in people with myeloid leukemia, neurofibromatosis...ag to prevent the addition of a farnesyl group and tested the effect in cells grown in the laboratory, progerin did not anchor itself to the inner nuclear mem...Seaweed yields new compounds with pharmaceutical potential
...oration, and small quantities of each extract were tested against a battery of pharmaceutical drug targets, including malarial parasite, tuberculosis-causing bacteria, and several cancers. Typically, these tests involve exposing live, disease-causing cells -- parasites, bacteria or cancer cells -- to an ...Male elephants woo females with precise chemistry
...les to detect the ending of musth. The team then tested the effect the various enantiomer ratios had on th...or in a non-reproductive "luteal" phase. They also tested young and old males. It found that low concentrations of frontalin, represented when the enantiomer ...Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
...ng clinical studies, while a few already are being tested in patients.A press conference on "Advances in Nan...d with a hormone and cell-killing peptide is being tested to image, target and destroy primary and metastatic breast cancer cells. A novel kind of "nanocomp...HIV drug resistance increasing in UK and among highest in the world
...tional data on HIV positive cases, the researchers tested patients for resistance to the antiretroviral drugs before embarking on the treatment. Tests were conducted on 2,357 patients between 1996 and 2003 ?thus researchers could track if there were changes to resistance patterns as time went on. They foun...Model identifies genes that induce normal skin cells to become abnormal
...d by the immune system. The group's current study tested the hypothesis that the microenvironment of metastatic melanoma cells could induce benign skin cells to become cancer-like. The researchers seeded a particularly aggressive form of human metastatic melanoma cells onto a three-dimensional collagen m...Older female fish prefer imperfect male mates, study finds
... example, the average age of the females and males tested for preference for symmetrical faces was only 20.3 years and 19.5 years, she said. The swordtail fish used in the latest research are two species of Mexican fish, Xiphophorus cortezi and Xiphophorus malinche. Because the genetic makeup of these fish ...Researchers show how air pollution can cause heart disease
...o measure tension in the arteries, the researchers tested how the neurotransmitters serotonin and acetylcholine affected the aortic arches of PM2.5-exposed mice differently than those of controls. The arteries taken from exposed mice were less elastic than the control group, constricting more in the presenc...Compound from marine bacteria shows potential as multiple myeloma therapy
...o, the developer of NPI-0052. The compound will be tested as a single agent and subsequently in combination ... the proteasome in different ways, the researchers tested them together on myeloma cells. They found that the cancer cells were killed more effectively by the......Now, Andrew Steele and colleagues from Denver have tested a computerized physician order entry (CPOE) system in a US hospital's outpatient clinic. The main purpose of the study was to determine the impact of using computerized alerts to improve the prescribing of medications in the outpatient setting. Studi...