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Tag: "tested" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

...tions that the superbowl molecule has not yet been tested in animals or humans. Until then, no one knows yet when this experimental molecule will actually enter the consumer market, but any useful application is likely to take five to ten years, the researcher estimates. Administration of the molecule for d...

Wisconsin scientists grow critical nerve cells

...y, it will likely be many years before they can be tested in humans, Zhang says. ...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...0 gel or a matched placebo gel. CVL specimens were tested for their ability to prevent HIV and HSV infection of susceptible human cells in culture. Levels of inflammatory cytokines were also measured as markers of acute inflammation. Analyses showed that CVL obtained after the application of PRO 2000 gel r...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

... week. As the young mice matured, the researchers tested their blood glucose (sugar) after meals. At age 2 months, the results were similar between the two groups. But over time, differences began to unfold. When 4 months old (comparable to human adolescence), the low-birth-weight babies began showing high...

Neuronal 'traffic jam' marks early Alzheimer's disease

...ningful swelling in the neurons." The researchers tested whether they could enhance the pathology they observed in the mice and humans by reducing the levels of a key transport protein, kinesin-1, the cell's principal molecular motor for transporting proteins. "We made a modest reduction in the level of a ...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...hy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin Coombes, Ph.D., and Jeffrey Morris, Ph.D., from M. D. Anderson Cancer Center, and Sarah Edmonson, M.D., from Baylor College of Medicine). They say the issue centers on how t...

New species from old data

...hy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin Coombes, Ph.D., and Jeffrey Morris, Ph.D., from M. D. Anderson Cancer Center, and Sarah Edmonson, M.D., from Baylor College of Medicine). They say the issue centers on how t...

Cracking the olfactory code in bees

...hy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin Coombes, Ph.D., and Jeffrey Morris, Ph.D., from M. D. Anderson Cancer Center, and Sarah Edmonson, M.D., from Baylor College of Medicine). They say the issue centers on how t...

Signaling protein builds bigger, better bones in mice

...hy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin Coombes, Ph.D., and Jeffrey Morris, Ph.D., from M. D. Anderson Cancer Center, and Sarah Edmonson, M.D., from Baylor College of Medicine). They say the issue centers on how t...

Newly discovered virus linked to childhood lung disorders and Kawasaki disease

...sfrom 895 symptomatic children under age 5 who had tested negative forother viral infections. They found 79 ...ts butonly one (5 percent) of the comparison group tested positive for theNew Haven coronavirus.In an accompanying editorial, Kenneth McIntosh of Harvard Univ...

Study Links Ebola Outbreaks To Animal Carcasses

...seases, the study found that many animal carcasses tested for Ebola between 2001 and 2003 produced positive ...asses, 21 gorilla, chimp and duiker carcasses were tested for the Ebola virus, with 14 samples being found positive. In 11 cases, instances of human infection...

Bacteria collection sheds light on urinary tract infections

... causing UTIs with bacteria found in animals. They tested E.coli samples from dogs, cows, sheep, water and turkeys. The researchers then compared the samples genetically to the UTI causing bacteria and found that a sample from a cow matched well with the E.coli found in humans. The team also found that the ...

U-M scientist to talk about tissue engineering at AAAS

...erapies, too." These approaches are not yet being tested in humans, but Krebsbach said some small clinical trials are under consideration. If the combination therapy approach works, Krebsbach said the next step would be working with engineers to develop anatomically correct scaffolding with the same curva...

Genome-wide mouse study yields link to human leukemia

...ed as methylated. In the study, the research team tested 2447 fragments in each animal. They found anywhere from 45 to 209 (.8 percent to 8.5 percent) of the fragments methylated in the mice with cancer, but only one or two methylated fragments in the other mice. "Interestingly, that same range of methyla...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...vationlook like."A patient's blood could easily be tested for specific diagnosticmarkers that would indicate his level of iron deprivation, he said.With diagnostic markers in place, physicians could translate theseverity of the disease into the appropriate treatment....

Novel Enzyme Shows Potential As An Anti-HIV Target

...r of nonhistone proteins. Ott and colleagues first tested the ability of all seven SIRT proteins to deacetylate Tat by placing them in a test tube with Tat proteins. Though three SIRT enzymes caused Tat acetylation, only one, SIRT1, is a nuclear enzyme, like Tat, suggesting that SIRT1 might work similarly i...

Mitochondrial DNA mutations play significant role in prostate cancer

...als can stimulate cell growth, the researchersthen tested the tumors for oxygen radical production. The tumors withthe mutant mtDNAs generated significantly more oxygen radicals thanthose with normal ntDNAs, suggesting that this may be an importantcontributory factor in the mitochondrial enhancement of pros...

Researchers reveal the infectious impact of salmon farms on wild salmon

...is study goes far beyond a theoretical model. They tested the model in the real world, using an enormous data set, and saw the same patterns. It is a very thorough analysis." "We've tried to be very careful and conservative ?but there is potential for a major impact on the survivorship of the migrating sal...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

...rgic response. Dr. Saxon and his colleagues first tested GFD in blood donated by people allergic to cats. T... in cat saliva and dander.?/p> The researchers tested GFD in two different types of allergic mice. One set was genetically engineered to have human cat-al...

Gene variations explain drug dose required to control seizures

...vide a direction for a dosing scheme that could be tested in the clinic to assess whether pharmacogenetic diagnostics can improve dosing decisions, he added. In particular, it may be clinically relevant to determine whether physicians can safely increase drug doses more rapidly for some patients. Such a tri...

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