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Tag: "test" at biology news

Wisconsin scientists grow critical nerve cells

...," says Zhang. The next step, Li says, will be to test if the newly generated neurons can communicate wit...splanted into a living animal. The team will first test the neurons in chicken embryos. While the new results are promising and provide access to critical ...

W.M. Keck Foundation funds study of friendly microbes

... information encoded in genomes and experimentally test predictions about gene functions that come from ou... of new species, without having to culture them in test tubes. They are also developing new computational methods for mining genome sequence data so that b...

Neuronal 'traffic jam' marks early Alzheimer's disease

...ow to cause Alzheimer's disease in people, to then test for transport defects, and then study whether those defects produce pathology similar to that seen in Alzheimer's. One of the questions they will also ask is whether amyloid plaques poison the transport machinery. If the experiments do, indeed, confi...

Scientists Replicate Hepatitis C Virus in Laboratory

...dy the life cycle and biology of this virus and to test potential antiviral compounds, which may lead to new therapies for the liver disease that results from infection with HCV. Scientists at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), one of the National Institutes of H...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...gling science of proteomics to devise a diagnostic test for cancer. In the February 16 issue of the Journ... Anderson Cancer Center detail why an experimental test intended to identify early ovarian cancer from a small sample of blood is unlikely to lead to a reli...

New species from old data

...gling science of proteomics to devise a diagnostic test for cancer. In the February 16 issue of the Journ... Anderson Cancer Center detail why an experimental test intended to identify early ovarian cancer from a small sample of blood is unlikely to lead to a reli...

Cracking the olfactory code in bees

...gling science of proteomics to devise a diagnostic test for cancer. In the February 16 issue of the Journ... Anderson Cancer Center detail why an experimental test intended to identify early ovarian cancer from a small sample of blood is unlikely to lead to a reli...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

... microarrays, could result indifferent profiles.To test the feasibility of multi-lab microarray studies, the NCI’sDirector’s Challenge program set up this preliminary study to compareresults between labs. Twelve different tumor tissues, five cancer celllines, and five purified RNA samples were prepared, b...

Signaling protein builds bigger, better bones in mice

...gling science of proteomics to devise a diagnostic test for cancer. In the February 16 issue of the Journ... Anderson Cancer Center detail why an experimental test intended to identify early ovarian cancer from a small sample of blood is unlikely to lead to a reli...

Scientists detect probable genetic cause of some Parkinson's disease cases

...indings could lead to the development of a genetic test to detect themutation in individuals at risk. The research team includesinvestigators at the National Institute on Aging (NIA) and scientistssupported by the National Institute of Neurological Disorders andStroke (NINDS). Parkinson's disease,which a...

Genome-wide mouse study yields link to human leukemia

...rred to as fragments, show up as smudgy blobs on a test film. If a fragment is dark and definite, it is not methylated. If, on the other hand, it loses at least 30 percent of its intensity, it is regarded as methylated. In the study, the research team tested 2447 fragments in each animal. They found anyw...

Novel Enzyme Shows Potential As An Anti-HIV Target

...T proteins to deacetylate Tat by placing them in a test tube with Tat proteins. Though three SIRT enzymes caused Tat acetylation, only one, SIRT1, is a nuclear enzyme, like Tat, suggesting that SIRT1 might work similarly in living cells. Ott and colleagues went on to show that transcription via Tat occur...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

...in laboratory mice, as well as in human cells in a test tube, University of California, Los Angeles (UCLA)...rom reacting to cat allergen. The next step was to test GFD in mice that we had made allergic to the allergenic protein found in cat saliva and dander.?/p&#...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

... increased risks," she says.So Reinisch decided to test the chemical cocktail, in similarproportions to those found in Brick, on a species of surf clam readilyavailable in the waters off of her Cape Cod lab. The species is famousamong scientists as a model for the study of cellular processes thatare commo...

Study identifies predictors of HIV drug resistance in patients beginning triple therapy

... increased risks," she says.So Reinisch decided to test the chemical cocktail, in similarproportions to those found in Brick, on a species of surf clam readilyavailable in the waters off of her Cape Cod lab. The species is famousamong scientists as a model for the study of cellular processes thatare commo...

Mouse brain tumors mimic those in human genetic disorder

...ontrast enhancement on MRI alone is not a reliable test of tumorprogression," Gutmann says. "If we rely on contrast enhancement inchildren with NF1 optic pathway gliomas, we may be treating kids whodon't need to be treated. Using this mouse model, we hope to continueto hone in on more accurate diagnostic,...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...redicted the tumor's response. Researchers plan to test the technique with breast cancer and head and neck cancer. In addition to Ross, U-M study authors are Bradford Moffat, Ph.D., assistant professor of radiology; Thomas Chenevert, Ph.D., professor of radiology; Theodore Lawrence, M.D., Ph.D., Isadore ...

Gene variations explain drug dose required to control seizures

...arkinson's disease, for example, a pharmacogenetic test might assist physicians in prescribing the drug dose that will balance short-term control of tremors with long-term drug side effects that eventually render the disease untreatable, he said. Patients' genetic makeup might also influence the dose of c...

Purdue proves concept of using nano-materials for drug discovery

...alf-inch square that might contain up to a million test chambers, or "reactors," each capable of screening...e how cell membranes function on chips in order to test the potential effectiveness of new drugs to treat diseases. Membranes, which surround cells and regu...

Scientists rid stem cell culture of key animal cells

...ely used for human embryonic stem cell culture, to test whether FGF2 preserves undifferentiated stem cells in the absence of BMP. The result was that "the cells looked perfect." Xu says he has grown the resulting stem cells in the desired undifferentiated state for almost a year. Although the new work "d...

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