Cracking the genetic code for control of gene expression
...es are expressed in tightly controlled spatial and temporal patterns but we do not know the code by which the expression is regulated. In this post-genomic era, the next big goal is to decipher the genetic code of regulation of gene expression. At the University of Helsinki the researchers have been interest...Memory loss affects more of the brain than previously thought
...ound altered functionality in both the frontal and temporal lobes of the brain. Previous studies looking at st...arliest stages of AD tends to be restricted to the temporal lobe, a region critical to long-term memory formation. "Involvement of both the frontal and tempora...Everything in its place: Researchers identify brain cells used to categorize images
...e areas of the brain, particularly the frontal and temporal lobes, have been associated with visual categoriza...ed brain areas, the parietal cortex and the middle temporal area, while the monkeys played the categorization game. The activity of parietal neurons mirrored th...The brain's executive is an 'event planner'
...ccur as the consequence of actions in a particular temporal order; we rarely consider the temporal sequence of motor actions themselves," wrote Mushiake and colleagues. "The properties of PFC neurons...Himalayan forests disappearing
...ccur as the consequence of actions in a particular temporal order; we rarely consider the temporal sequence of motor actions themselves," wrote Mushiake and colleagues. "The properties of PFC neurons...The brain's motivation station
... as the learning-related hippocampus in the medial temporal lobe (MTL) of the brain. Activation prior to scene visualization suggests that the brain actually prepares in advance to filter incoming information rather than simply reacting to the world. Activation of the MTL is associated with higher brain func...How nature tinkers with the cellular clock
...le have been conserved over one billion years, the temporal regulation of this process has evolved remarkably ...uch a central process." To have a safety net when temporal control at the gene level fails, cells also regulate the activity of cell cycle proteins directly, s...Study offers window into human behavior, brain disease
...generate in ALS and specific memory-forming medial temporal lobe neurons die in early Alzheimer's disease. "We hope to add von Economo neurons to that list," says Seeley. "It's a pretty important list to fill in, but for FTD there just hasn't been a good candidate until now. We think we've found it, and th...Insulin receptor stops progression of Alzheimer's disease
...striking effect in preserving the hypothalamus and temporal lobes, areas of the brain responsible for memory, learning, and behavior. In these brain regions, PPAR alpha and PPAR gamma were effective in reducing amyloid gene expression. PPAR delta had the most benefit for reducing oxidative stress and improvin...Critical hearing gene helps send auditory messages to brain
...added, "in the sense that it operates with extreme temporal precision." In mammals, the hearing organ, or co...uine sensory cells transmitting information on the temporal structure and intensity of sound to the central nervous system," Petit said. While outer hair cell...Study finds the air rich with bacteria
...g bacteria. "This information may help explain temporal spikes, which is important in bioterror surveillance," adds Eoin Brodie, also with Berkeley Lab's Earth Sciences Division. "A spike may not be due to a biological attack, but to normal weather fluctuations that draw bacteria up from their natural res...Brain regions do not communicate efficiently in adults with autism
...tivity in the left hemisphere, particularly in the temporal lobe of the persons with autism within two different frequencies of brain waves, the delta and theta bands. This part of the brain is associated with language, which is impaired in many people with autism. A global pattern of decreased neural...Slow brain waves play key role in coordinating complex activity
...ectrodes on the surface of the brain's frontal and temporal lobes to precisely localize the source of the seizure so it could be removed in a subsequent surgical procedure. Knight, Canolty and their UC Berkeley colleagues then recorded activity in response to sounds and visual stimulation. Several hours of ...New dyslexia theory blames 'noise'
...roscience study], which used different spatial and temporal patterns." ...One signal elicits thousands of answers
...ere unknown - in 2,244 proteins and observed their temporal dynamics. All these phosphorylation sites are now ...ons of all proteins in living cells - and in their temporal dynamic. For this approach cell cultures were stimulated by EGF for different lengths of time. The "...Gene therapy inhibits epilepsy in animals
...an area that is critical to generating seizures in temporal lobe epilepsy, the most common type of epilepsy in children and adults. GABA(A) receptors are made up of five subunits--proteins that play important roles in brain development and in controlling brain activity. Previous animal research by Dr. Brook...Neural bottleneck found that thwarts multi-tasking
...d sampling method allowed them to characterize the temporal pattern of activity in specific brain areas. Th...between tasks, we did not see this delay. "This temporal delay is the essence of dual-task interference for tasks that require actions. By using time-resolve...Sleep enforces the temporal sequence in memory
...r it is not clear how the brain keeps track of the temporal sequence in such memories: did Paul spill a glass ... associated consolidation of memories enforces the temporal structure of the memorized episode that otherwise might be blurred to a timeless puzzle of experienc...Do fruit flies have free will?
...en stations. However, the analysis showed that the temporal structure of fly behavior is very different from random noise. The researchers then tested a plethora of increasingly complex random computer models, all of which failed to adequately model fly behavior. Only after the team analyzed the fly behavi...... details new data on host species, prevalence, and temporal and geographical variation of avian influenza in wild migratory birds in Europe. Seven previously unknown host species for H5N1 were identified, including four species of goose and the common gull, and dabbling ducks were found to harbor all but two ...