Newly-discovered class of genes determines ?and restricts ?stem cell fate
... new since he suggests that a single gene can both tell a cell what it should become and restrict its fate by preventing differentiation. The ability of a single biochemical factor or complex of factors to have this dual role may represent a new general paradigm for developmental and stem-cell biology. "M...First 'atlas' of key brain genes could speed research on cancer, neurological diseases
...rent parts of the brain pinned down.The map should tell scientists studying different parts of the brain,which transcription factor (TF) genes regulate the development of thatbrain region, and which of them to investigate as possible causes ofbrain tumors and other diseases.The Dana-Farber researchers alr...Gene Therapy For Parkinson's Disease Moves Forward In Animals
...cal known as dopamine, which carries messages that tell the body how and when to move. In tests with 31 monkeys, including a control group, scientists inserted copies of a gene to produce GDNF into a region in the front part of the brain called the striatum. They then induced Parkinson-like conditions by ...Studies reveal methods viruses use to sidestep immune system
...y the gene is essential to turning on signals that tell the cell to mount an immune response. Cells with the mutated RIG-I protein were unable to initiate immune signals, abolishing the host cells' defenses to HCV. When HCV infects a cell, the RIG-I protein physically binds the virus genetic material. RI...Gene therapy for Parkinson's disease moves forward in animals
...cal known as dopamine, which carries messages that tell the body how and when to move. In tests with 31 monkeys, including a control group, scientists inserted copies of a gene to produce GDNF into a region in the front part of the brain called the striatum. They then induced Parkinson-like conditions by ...FDA Approves New Drug to Treat Type I and Type II Diabetes
...ses. Symlin should not be used if patients cannot tell when their blood sugar is low, have gastroparesis (slow stomach emptying), or are allergic to pramlintide acetate, metacresol, D-mannitol, acetic acid, or sodium acetate. Side effects associated with Symlin include but are not limited to nausea, vom...Programmable cells: Engineer turns bacteria into living computers
...ganisms in laboratory tests. "The bull's-eye could tell you: This is where the anthrax is," said Weiss. The researchers published their results in the April 28 issue of Nature. In addition to Weiss and Basu, authors of the paper are postdoctoral researcher Yoram Gerchman at Princeton and professor of che...Researchers devise way to mass-produce embryonic stem cells
...ines, to the stem cells. The cytokines essentially tell the stem cells to stay in their undifferentiated state. The difference between growing stem cells in a flask vs. the bioreactor is that the cells grown in the bioreactor could grow in three dimensions, while cells growing on a flat surface ?the bott...Nanoscale Diagnostic Sets Sights on Alzheimer's
...s the sensitivity of the test and its potential to tell doctors a patient carries the ADDLs. According to the researchers, BCA is about 1 million times more sensitive than the next best thing ?standard enzyme-linked immunoassays (ELISAs). ELISAs do not have the sensitivity required to detect ADDLs in cer...New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal
...d. “It doesn’t give you the full story ?it doesn’t tell you, for example, how quickly the bacteria are killed.?/p> So UF scientists developed a system of pumps they can use to expose bacteria to changing concentrations of an antibiotic, mimicking the concentration profile present in a patient at the a...Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive
You just can't tell where you might find love these days. A team led by a neuroscientist, an anthropologist and a social psychologist found love-related neurophysiological systems inside a magnetic resonance imaging machine. They detected quantifiable love responses in ...Study reveals new technique for fingerprinting environmental samples
...t the demands of the setting and, accordingly, can tell us about what's happening in an environment without knowing the identities of the microbes living there." The EGT fingerprints capture a DNA profile of a particular niche and reflect the presence and levels of nutrients, and pollutants, as well as f...Researchers unlock mechanism creating jigsaw puzzle-like plant cells
...s resembling jigsaw puzzle pieces. These proteins tell one part of a cell to grow outward while telling its neighbor to recede or indent itself in a finely tuned biological dance. The results are structures that, despite their delicate appearance and slenderness, provide the strength necessary to allow t...Scientists journey to southern Africa to unravel the secret world of elephant communication
...tial mates far away," she says. "Or maybe they can tell if a predator is in the vicinity by picking up sei...that's visible on a spectrogram, making it easy to tell if an elephant, rhino or giraffe has walked by. "We think we can tell the difference between elepha...Measuring hormone cuts antibiotic use in half in pneumonia patients
...elay treatment in order to wait for lab results to tell them whether a patient's pneumonia is bacterial or viral, so they start all patients on antibiotics, Dr. Tamm said. "Once the treatment is started, it is usually continued for 10 to 14 days, because nobody knows when you can stop without a risk for t...One gene links newborn neurons with those that die in diseases such as Alzheimer's
...ep was to label the two kinds of cells in order to tell them apart. The replaceable neurons send projections to another part of the brain a few millimeters away from the high vocal center to form part of the brain pathway that controls muscle movements related to singing. The neurons that are not replace...The circadian clock: Understanding nature's timepiece
... also unique temporal niches, as any cat owner can tell you. ...Finding hidden invaders in a Hawaiian rain forest
...ingerprints from the plant leaves and used them to tell which species dominated specific areas. We employed the recently upgraded NASA Airborne Visible and Infrared Imaging Spectrometer (AVIRIS) to measure leaf nitrogen and water content from the aircraft, and corroborated the data on the ground. The fing...Scientists use manufacturing methods to reconstruct mastodon
...pretation of this animal's history and what it can tell us about late Pleistocene events." Leading up to the exhibit opening, the museum is offering a semester-long series of public educational events, aimed at both adult and family audiences, exploring the theme, "Mastodons and the Ice Age." A schedule ......limate statistics from the north Pacific Ocean and tell you how the elk are doing in Banff National Park. The University of Alberta doctoral student is the first researcher to show a correlation between the North Pacific Oscillation (NPO) and a mammal population. Based on many climate-related ocean measu...