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Tag: "techniques" at biology news

Candida albicans Genome Fully Annotated

...different cell types." Applying advanced research techniques that previously had been used to analyze liver and bone marrow transplant recipients, the team found that nine of 25 lung tissue specimens from five recipients contained small numbers of the male gender version of the type II pneumocytes. The proport...

Combination therapy leads to partial recovery from spinal cord injury in rats

... transplanted cells, and they plan to test similar techniques that start with undifferentiated embryonic stem (ES) cells instead of glial-restricted precursor cells. ES cells would be better for human studies than glial-restricted precursors because ES cells can be more readily obtained, Dr. Whittemore says. [...

Using nanoparticles, in vivo gene therapy activates brain stem cells

...leap forward in developing experimental, non-viral techniques to study brain biology and new therapies to address some of the most debilitating human diseases." Viral vectors for gene therapy always carry with them the potential to revert back to wild-type, and some human trials have even resulted in fatalitie...

Modified collagen could yield important medical applications

...lagen by using intense heat or chemical reactions, techniques that may damage the protein or limit its safe use in humans. Yu's method, however, requires only physical mixing of collagen with even smaller molecules called collagen mimetic peptides. "That's the beauty of this," said Yu, an assistant professor i...

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

...r research using structure-based virtual screening techniques and high throughput equipment to screen for potential inhibitor compounds against the Dam enzyme. ...

Unusual antibiotics show promise against deadly 'superbugs'

...lagen by using intense heat or chemical reactions, techniques that may damage the protein or limit its safe use in humans. Yu's method, however, requires only physical mixing of collagen with even smaller molecules called collagen mimetic peptides. "That's the beauty of this," said Yu, an assistant professor i...

Scalpel-free surgery could reduce risk of HIV and hepatitis exposure for health care workers

...ves to needles and knives. We advocate using these techniques whenever possible in high-risk settings to further...l transmission," added Makary. Sharpless surgical techniques include laparoscopy, electrocautery to replace scalpel incisions, and skin clips or glue instead of ...

Breakthrough: Scientists create world's tiniest organic particles

... E. Exner. Until now, DeSimone said, most current techniques for particle formation were incompatible with organic materials. That was because they involved baking, etching or processing robust metals and such with solvents that would have destroyed far more fragile organic matter such as genes or drugs. The ...

How monarch butterflies are wired for navigation

...ay in using their "sun compass." The researchers' techniques include molecular analysis of butterfly brain proteins, as well as flight tests in which the scientists manipulated the light reaching their insect subjects and measured the navigational response. In their studies, the researchers discovered that ul...

New tool reveals secrets of migrating cells

...ck out patterns of movement easily, so statistical techniques are needed to identify cells with different patterns of movement. As an immunologist, Robey focuses on the lives of T cells produced in the thymus and distributed via the bloodstream to the lymph nodes, whence they move into the body's tissues. Her ...

Anthrax inhibitors identified by Burnham team

...ighly sensitive nuclear magnetic resonance ("NMR") techniques developed in Dr. Pellecchia's laboratory, the scientists were able to identify a scaffold that served as a template for designing a preferred structure for small-molecule inhibitors of LF. Lead compounds were synthesized and validated as highly poten...

Researchers seek to discover what really happens when a virus enters the body

...an achieve results in hours instead of days, their techniques could be used in clinical and field settings to quickly identify known viruses, or to map unknown viruses to existing profiles to better predict their behavior and start appropriate treatment. Ultimately, their work should contribute to what starts...

Spiders help scientists discover how muscles relax

...een possible. It took several years to refine the techniques required to preserve the thick muscle filaments in their relaxed state. Even then, the researchers faced mathematical difficulties in calculating a three-dimensional map of the filaments. In 2004, using a new approach that Edward Egelman at the Unive...

Microscopic brain imaging in the palm of your hand

...combines a pair of powerful optical and mechanical techniques into one device that fits in the palm of the hand. The results appear in the September 1, 2005 issue of Optics Letters, a journal published by the Optical Society of America. Researchers want to image individual cells inside living subjects because ...

New mitochondrial DNA gene chip may be early cancer diagnosis tool

...RN), has validated the measurement accuracy of new techniques that use mitochondrial DNA as an early indicator f...efficiency and reliability of potential diagnostic techniques using biomarkers before further clinical evaluation in other laboratories of the EDRN. The lab found...

Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure

...turn Orf2 into a more customized tool by using the techniques of genetic engineering to narrow its activity and tell it exactly which reactions to carry out. “The big advantage that we have with our system is that it’s a small, soluble, easy-to-work-with bacterial protein that seems to be able to do reactions ...

Stem cell training program to make its Stanford debut

...turn Orf2 into a more customized tool by using the techniques of genetic engineering to narrow its activity and tell it exactly which reactions to carry out. “The big advantage that we have with our system is that it’s a small, soluble, easy-to-work-with bacterial protein that seems to be able to do reactions ...

Study casts doubt on 'Snowball Earth' theory

...was not ice-bound A study that applied innovative techniques to previously unexamined rock formations has turne...om southeastern Brazil and applied lipid biomarker techniques to identify prehistoric organisms based on the fatty remains of their cell membranes. The team, whi...

Gap-climbing fruit flies reveal components of goal-driven behaviors

...xpensive research. Using noninvasive neurogenetic techniques for the analysis of the underlying motor-control system, Pick and Strauss showed that in order to reach a goal, flies compose complex motor patterns from different behavioral subunits. In their genetic analysis, the researchers found mutant flies wit...

Investigating 'brain shrinkage' in alcoholics

...coholic subjects. Scientists used modern molecular techniques to study the control mechanisms (genes) and building blocks (proteins) of the main component of white matter ?the myelin. They found that the expression of genes that control the manufacture of structural proteins of the myelin was reduced in the alc...

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