NIAID researchers show how promising TB drug works
...s, Inc. (Madison, WI). This was the first time the technique has been used to identify a protein involved in TB drug resistance, notes Dr. Barry. Using the NimbleGen technique, which effectively re-sequences the entire genome of the bacterium, the scientists quickly pinpointed the protein altered in the PA-82...Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds
A new gene therapy technique that has shown promise in skin disease and hemophi...ic protein made by those genes. The gene therapy technique Rando and postdoctoral fellow Carmen Bertoni, PhD, used was developed by Michele Calos, PhD, associa...Center releases new public survey on stem cells
...ed to imagine two scenarios - the development of a technique to isolate ESCs without destroying embryos, or a major advance in treating disease based on embryonic stem cell technologies. About 25 percent of respondents who initially favored the current policy or a complete ban of ESC research indicated that i...Study reveals genomics of inflammation from severe injury
...rch team described the development of a microarray technique to analyze the entire genome of white blood cells from healthy volunteers and critically injured patients. Next, the team plans to study gene and protein activity in the white blood cells of a large group of trauma and burn patients over longer perio...Study Unlocks Insects?Secret for Love in the Dark
...rch team described the development of a microarray technique to analyze the entire genome of white blood cells from healthy volunteers and critically injured patients. Next, the team plans to study gene and protein activity in the white blood cells of a large group of trauma and burn patients over longer perio...New neurons take baby steps in the adult brain
...lt neurons. In the mouse experiments, Goh used a technique to alter the genetics of single cells in order to change new neurons' ability to accumulate chloride ions (and thus to manipulate their response to GABA) and to make them glow with a green protein to ease their identification in the adult brain. Ge m...Magnetic probe successfully tracks implanted cells in cancer patients
...a patients. "Our results show that the MRI-based technique was more accurate than tracking the cells using radioactivity and that ultrasound failed to accurately guide injection of the cells into lymph nodes in half of the patients," says Bulte, an author on the report, which appears in the November issue of...DNA self-assembly used to mass-produce patterned nanostructures
... circuits, as is done in the current manufacturing technique of photolithography, the Duke researchers used DNA strands to create grids less than one ten-millionth of a meter square. The smallest features on these square DNA lattices are approximately five to 10 billionths of a meter (nanometers), according to...Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
...related with the greater IGF1R expression. "The technique could be used for detection and it could be used f...ncer proteins." The researchers plan to test the technique with additional breast cancer markers, as well as with markers for other cancers. They are also plan...Researchers know what you were about to say; fMRI used to detect memory storage and retrieval
...rning process for each category. They developed a technique that could track the brain activity corresponding ...ipants retrieved memories. As they remembered, the technique provided a second-by-second readout of how the brain searched for information. So participants woul...SLU researchers uncover direct evidence on how HIV invades healthy cells
...ed from a single infected cell. "We will use this technique in our ongoing studies of the effects of drugs in the process of assembly and disassembly of the viral DNA integrase complexes," Bera said. ...Zooming in on the protein-conducting channel
...rles Brooks of the Scripps Research Institute. The technique provides dynamic information on the multitude of vibrations and motions that complex molecules preferentially undergo. NMFF analysis revealed that the cryo-EM data were best explained by a model in which the two PCC clamshells were joined in a “fron...Scientists use stem cells to grow cartilage
... living tissue. The scientists also believe this technique could be used in cosmetic and reconstructive surge...grafts from other parts of the body. With this new technique doctors would potentially be able to take stem cells from the patient, grow them in a laboratory, an...Genetic testing still smart choice, despite uncertainties
...ican Society of Reproductive Medicine, reveals the technique is actually highly reliable. But because there is a slim chance a genetic abnormality can cause doctors to misdiagnose embryos, some concerns still need to be addressed, the researchers said. Preimplantation genetic diagnosis has been used for mor...Bugs expose underground carbon traffic system 10 times more important than fossil fuel burning
...e (a stable isotope of carbon, 13C) for 7 hours, a technique called pulse labelling. Concentration of 13C in cores was then analysed. The soil cores which were exposed to the mites were found to have 32% less 13C than the control cores. This showed that Collembola's consumption of the arbulscar mycorrhizal my...Penn Surgeons Use Completely Robotic Surgery to Successfully Treat Prostate Cancer
...am and I have discovered that by using the robotic technique there is greater nerve sparing, which provides patients with the best chance for maintaining potency and continence.?br /> Robotic technology offers a number of advantages during surgery. For instance, the robotic “arms?filter even...Scientists learn to predict protein-stabilizing ability of small molecules
...am and I have discovered that by using the robotic technique there is greater nerve sparing, which provides patients with the best chance for maintaining potency and continence.?br /> Robotic technology offers a number of advantages during surgery. For instance, the robotic “arms?filter even...Cells from amniotic fluid used to tissue-engineer a new trachea
...ambs while still in the womb. The tracheal repair technique is one of several tissue-engineering approaches pioneered at Children's that use the fetus's own cells, drawn from the amniotic fluid that surrounds it, to create patches to fix birth defects -- in this case, even before birth. Pediatric surgeon Dar...Bare metal stents deliver gene therapy to heart vessels with less inflammation in animal studies
...'s Hospital of Philadelphia have developed a novel technique to attach therapeutic genes to a stent's bare metal surface. This technique allows the genes to help heal the surrounding blood vessels, while avoiding the inflammation caused ......ral cognitive functioning. The researchers used a technique called positron emission tomography, or PET, to gain insight into CX717's neurobiological role. The PET signal reflected the distribution and rate of metabolism of ingested radioactively labeled glucose in the monkeys' brain cells. By measuring regio...