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Tag: "technique" at biology news

A step toward the $1,000 personal genome using readily available lab equipment

...A polymer," write the Harvard scientists. The new technique calls for replicating thousands of DNA fragments attached to one-micron beads, allowing for high signal density in a small area that is still large enough to be resolved through inexpensive optics. One of four fluorescent dyes corresponding to the fo...

Color perception is not in the eye of the beholder: It's in the brain

...ght caused by the atmosphere. Williams turned the technique from the heavens back toward the eye to compensate for common aberrations. The technique allows researchers to study the living retina in ways that were never before possible. The pigment t...

Grasshopper love songs give insight into sensory tuning

...ir colleagues also concluded that their analytical technique could yield broader insight into the evolution of sensory circuitry. "Our approach presents a systematic way to uncover potential mismatches between the statistical properties of the natural environment and the coding strategy of sensory neurons. In...

Purdue's gold nanorods brighten future for medical imaging

...ping a new type of ultra-sensitive medical imaging technique that works by shining a laser through the skin to ...such as cancer, it is important to have a reliable technique that has sensitivity at the single-particle level," Wei said. "The gold nanorods demonstrate that Ch...

Bone marrow stem cells may heal hearts even years after heart attacks

...ect evidence of muscle regeneration using a simple technique to isolate mononuclear cells from the patient's ow...nts, it does not provide conclusive proof that the technique is effective. However, he noted that the results of large randomized, double-blinded clinical trials...

Scientists closer to new cancer detection method

...lorida researchers say they are a step closer to a technique to easily detect a wide variety of cancers before ... burst after they adhere to cancer proteins. The technique could enable doctors to search within extremely complex fluid or tissue samples to pinpoint biomarke...

Studies on human genome variation provide insight into disease

...mong genes in this region, we had to develop a new technique for our mutational analysis, which we call TAR cloning," explains Larionov. "Using this method, we isolated the SPANX region from 200 individuals by recombination in yeast." Based on their results, the authors speculate that predisposition to p...

Housecat-sized Siberian tiger cubs get collared

...mong genes in this region, we had to develop a new technique for our mutational analysis, which we call TAR cloning," explains Larionov. "Using this method, we isolated the SPANX region from 200 individuals by recombination in yeast." Based on their results, the authors speculate that predisposition to p...

New cell transplantation technique restores insulin production in diabetics

Researchers are using a new cell transplantation technique to restore the cells that produce insulin in patie..., where the islet cells are injected. The sandwich technique is so-called because of the layered applications of gelfoam and coil used to close the access site."...

Minimally Invasive Cancer Treatments Highlighted

...s 91% cancer-specific survival at 2 years. The RFA technique successfully killed the tumor inside the lung without surgery in 93% of the cases. (Author, Lencioni) ...

Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue

...logy Licensing (OTL). He also has patented another technique that uses pulses of near-infrared light to shake the DNA molecule loose from the carbon nanotube after they've entered the cell. The idea is to use the nanotube to deliver therapeutic molecules of DNA, RNA or protein directly into the cell nucleus to...

UT Southwestern researchers develop screening test for cells that activate immune system

...uture cancer-fighting vaccines. The new screening technique can scan thousands and even millions of compounds to identify those that activate dendritic cells, which are on constant recon patrol throughout the body to scout out cancerous or infected cells and alert the immune system. "Our assay is unique from...

Biotechnology's newest chemical tool

...chemical toolbox, researchers have developed a new technique that will allow them to modify specific sequences ...thyl source. Since the chemistry is the same, this technique is likely to be applicable to those biomolecules as well, further expanding its utility. Klimasauska...

Customized gene chip provides rapid detection of genetic changes in children's cancer

...delphia and Thomas Jefferson University, say their technique may be readily adapted for other types of cancer. ... issue of Genome Research. One advantage of their technique is its flexibility, said co-author John M. Maris, M.D., a pediatric oncologist at The Children's Hos...

Researchers learn how blood vessel cells cope with their pressure-packed job

...fibers." Indeed, when Chien's group used a genetic technique to increase the activity of Rho, those cells grew stress fibers in the healthy direction at a lower threshold of stretching. "Until now, it has not been shown that there is an equivalence and cooperation between mechanical and biochemical stimuli t...

'Smart' nanoprobes light up disease

...vasive surgery. The probe's design makes use of a technique called "quenching" that involves tethering a gold nanoparticle to the quantum dot to inhibit luminescence. The tether, a peptide sequence measuring only a few nanometers, or billionths of a meter, holds the gold close enough to prevent the quantum do...

Regenerating worms help elucidate stem cell biology

...e organisms." To find out, the scientists used a technique known as RNA interference to specifically turn off the piwi gene in planaria. When they did this, they found that worms had the same defects as those whose neoblasts have been destroyed by radiation -- head regression, curling, and the inability t...

Research Permits First-Ever Visualization of Psychological Stress in the Human Brain

...d metabolism induced by neural activation, using a technique that is sensitive to the oxygenation levels in blood. “The fMRI technique employed in our study ?arterial spin labeling ?can measure cerebral flood-flow directly,?states John...

Researchers offer proof-of-concept for Altered Nuclear Transfer

...x2 in mouse cells. They accomplished this with a technique called RNA interference, or RNAi. Here, short interfering RNA (siRNA) molecules are designed to target an individual gene and disrupt its ability to produce protein. In effect, the gene is shut off. Jaenisch and Meissner designed a particular form of...

Sickle cell disease corrected in human models using stem cell-based gene therapy

...e study's first author. "In this case, we used the technique to correct sickle cell disease, but it should be broadly applicable to use therapeutically in stem cells or malignant cells." ...

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