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Tag: "technique" at biology news

Using nanoparticles, in vivo gene therapy activates brain stem cells

...nisms of brain disease. "Until now, no non-viral technique has proven to be as effective as the viral vectors... brain. Using a new optical fiber in vivo imaging technique (CellviZio developed by Mauna Kea Technologies of Paris), the UB researchers were able to observe th...

Brown-Harvard team solves mobile DNA's surgical sleight-of-hand

...and Tom Ellenberger ?used X-ray crystallography, a technique that combines strong X-rays and sophisticated computer software, to create a 3-D digital image of λ-INT caught in the act of carrying out site-specific recombination. In complementary experiments carried out at Brown and published recently in the Pr...

Scripps research scientists identify infertility molecule

...y embryos implanted directly into their wombs (the technique of in vitro fertilization). Despite the existence of these therapies, however, the molecular mechanisms that govern female infertility are not completely understood. In fact, the cause of infertility is not always easy to diagnose. The American Soci...

Scripps research scientists solve structure of a critical innate immune system protein

...lving its structure via x-ray crystallography, the technique that Wilson and his colleagues employ. Because glycoproteins are covered with sugars, they are heterogenous due to the multiple glycoforms that make it harder, but not impossible, to form good crystals. A number of leucine-rich repeat proteins have b...

Scalpel-free surgery could reduce risk of HIV and hepatitis exposure for health care workers

... strategies such as 'sharpless' surgery-a surgical technique which uses high-technology alternatives to needles and knives. We advocate using these techniques whenever possible in high-risk settings to further protect health care workers from accidental transmission," added Makary. Sharpless surgical techniqu...

Researchers develop new method for facile identification of proteins in bacterial cells

...enzyme in a soup of hundreds of cell proteins. The technique avoids elaborate conventional sample preparation s..." he said. Halden and his colleagues tested their technique using Sphingomonas wittichii strain RW1, the only bacterium known to consume the backbone of toxic p...

New tool reveals secrets of migrating cells

...y the cells move to their final destination." The technique could allow researchers in many fields of biology ... Two-photon imaging is a variation on the standard technique of labeling cells with fluorescent dye and then hitting them with a laser that makes the dye glow an...

Using computers and DNA to count bacteria

...ead author Gans added. The Los Alamos team used a technique known as DNA re-association, separating the two strands of all the bacterial DNA in a soil sample, blending them, and measuring the time it takes for the correct halves to properly reconnect. As often happens at Los Alamos, where thousands of scient...

Comparison of Cocaine, Methamphetamine ‘Highs?Finds Differences

...ead author Gans added. The Los Alamos team used a technique known as DNA re-association, separating the two strands of all the bacterial DNA in a soil sample, blending them, and measuring the time it takes for the correct halves to properly reconnect. As often happens at Los Alamos, where thousands of scient...

Harmless virus may hold key to more effective HIV drug discovery

New phage display technique successful in identifying compounds that show potential to overcome drug resistance A simple, harmless virus might hold the key to the more effective and efficient development of HIV and anti-viral drugs, UCI chemical biologists have found. In orde...

Human embryonic stem cells have the potential to develop into eggs and sperm in the laboratory

...donate them, as this is a major limitation of this technique at the moment. We would then have completed the circle of making HESCs from eggs that came from HESCs ?what came first the chicken or the egg?!" ...

Vietnam war technology could aid elephant conservation

...dung balls - a very time consuming and error-prone technique - or aerial census techniques, which although they...t elephants in dense forest. As a result, the new technique could provide crucial data for reserve planning and management. "Conservation management would be im...

Spiders help scientists discover how muscles relax

...vement. Their work, which takes advantage of a new technique for visualizing tissues in their natural state, provides new insights into the molecular basis of muscle relaxation, and perhaps its activation too. "We have solved the structure of the array of miniature motors that form our muscles and found out ...

Scientists discover stem cell origin of neck and shoulders

...th international collaborators, used a new genetic technique to tag embryonic stem cells and then trace them to the adult animal. They discovered that instead of homogeneous groups of stem cells making up the bones of the shoulder and neck and another making the muscles, a newly-discovered group of stem cells ...

Microscopic brain imaging in the palm of your hand

...monstrated a promising, minimally invasive optical technique that can capture micron-scale images from deep in ...rescent-dye molecules used to mark the tissue. The technique gets rid of the background haze and reduces scattering, because molecules outside the area of intere...

Deep sleep short-circuits brain's grid of connectivity

...how the rest of the brain is responding." The new technique promises science a way to see how the different areas of the brain communicate, Tononi says. Beyond helping illuminate the secrets of consciousness, the new study, which was directed in part by Marcello Massimini, a research associate in the UW Psyc...

Frog peptides block HIV in lab study

...how the rest of the brain is responding." The new technique promises science a way to see how the different areas of the brain communicate, Tononi says. Beyond helping illuminate the secrets of consciousness, the new study, which was directed in part by Marcello Massimini, a research associate in the UW Psyc...

Thinking the pain away? Study shows the brain's painkillers may cause 'placebo effect'

...ith their PET scan images, which were made using a technique that reveals the activity of the brain's natural painkilling endorphin chemicals, also called endogenous opioids. Endogenous opioids bind to brain cell receptors called mu-opioid receptors, and stop the transmission of pain signals from one nerve c...

Measuring hidden parasites in falciparum malaria

A new technique for measuring hidden malaria parasites and assessing severity of disease is described in a paper published on Aug 23rd in PLoS Medicine . Researchers led by Professor Nick White from Mahidol University, Thailand, looked at patients with the most dan...

Micro-molecule plays big role in birth defects

... scientists say its greater value will be as a new technique to study the function and malfunction of microRNAs, more than 200 types of which are thought to exist in the human body. "We looked at limb development because it's a great place to demonstrate the technique," said Brian Harfe, Ph.D., an assistant p...

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