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Tag: "technique" at biology news

Spleen may be source of versatile stem cells

...oney for a clinical trial of theislet-regeneration technique in human patients. For more informationabout this project, go to http://www.joinleenow.org.Massachusetts General Hospital, established in 1811, is the originaland largest teaching hospital of Harvard Medical School. The MGHconducts the largest hospit...

Columbia research lifts major hurdle to gene therapy for cancer

...ences (PNAS), the researchers demonstrated thatthe technique works by incorporating it into a specially designe...mal cells unscathed. Genetherapy based on the new technique should also be effective for a widerange of tumors - such as ovarian, breast, brain (glioma), skin(m...

Priming embryonic stem cells to fulfill their promise

...a. She, Chien, and Flaim described intheir paper a technique that enabled them to identify the precise mixof pr... liver cells. Bhatia, Chien, and Flaimdesigned the technique with other cell biologists in mind so that anyof them could duplicate it with off-the-shelf chemical...

Scientists Replicate Hepatitis C Virus in Laboratory

...s replication,?says Liang. “We can also apply this technique to develop model systems for other similar viruses.?/p> HCV is a small, enveloped, single-stranded RNA virus in the family Flaviviridae. HCV is a major cause of liver disease in the United States and the world. One in a series of hepatitis viruse...

New Technique for Tracking Gene Regulators

...hey regulate just got a stepeasier thanks to a new technique developed by scientists at the U.S.Department of E...sity, have published the first results using their technique inthe December 29, 2004 issue of Cell, where they describe thehuman-genome binding sites of a regula...

“Nano-scissors?laser shows precise surgical capability

... therisk for tissue damage.Ben-Yakar’s nanosurgery technique used a series of low-energy“femtosecond?laser puls....Ben-Yakar developed the femtosecond laser surgery technique using thelaboratories and equipment of Dr. Robert Byer, a Stanford Universityprofessor, while doing ...

Breakthrough Microarray-based Technology for the Study of Cancer

...throughthe optical imaging of whole chromosomes, a technique with limitedsensitivity, resolution, quantification and throughput. Efforts inrecent years to use microarrays to overcome these limitations have beenhampered by inadequate sensitivity, specificity and flexibility of themicroarray platforms. As detail...

Study finds more than one-third of human genome regulated by RNA

...ntialtherapeutic uses of RNA. For example, using a technique known as RNAinterference, or RNAi, researchers are shutting off genes by deliveringinto cells artificial microRNA-like molecules called siRNAs. RNAi hasalready transformed how many labs are investigating gene functions, andsiRNAs are being developed ...

NYU researchers simulate molecular biological clock

...ntialtherapeutic uses of RNA. For example, using a technique known as RNAinterference, or RNAi, researchers are shutting off genes by deliveringinto cells artificial microRNA-like molecules called siRNAs. RNAi hasalready transformed how many labs are investigating gene functions, andsiRNAs are being developed ...

Molecular machine may lead to new drugs to combat human diseases

...llized previously, and the targeted trans-splicing technique has been used to repair hemoglobin infected with sickle cell anemia. The new structure provides scientists with tools to expand on ways to harness this molecular machine, Golden said. The other researchers on this study were Hajeong Kim, graduate st...

Jefferson Virologists Coax HIV Out of Hiding

...e to drugs and the body’s immune system. Ifthe new technique proves its mettle, the work could lead to improvedtreatments for HIV infection, and might be a step toward complete viraleradication. TheJefferson team reports its findings January 4, 2005 in the Journal ofClinical Investigation.Dr. Pomerantz, who i...

Color-blind method opens new doors in DNA sequencing

... green, yellow, and red. A common problem with the technique is that the color of light emitted by the dyes is similar. Even with complex computer programs to assist in deciphering the signals, this "cross-talk" between the dyes results in subtle variations that can cause nucleotides to be miscalled. The new ...

An HIV Protein Plays a Surprising Role in Gene Activation

...leagues turned to chromatin immunoprecipitation, a technique that detects proteins bound (directly or indirectly) to DNA. Working with three well-known effectors of transcription—an activator (Gal4-VP16), a transcriptional enhancer, and another viral activator called E1a—the authors show that what's true for y...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...the tumor's response. Researchers plan to test the technique with breast cancer and head and neck cancer. In addition to Ross, U-M study authors are Bradford Moffat, Ph.D., assistant professor of radiology; Thomas Chenevert, Ph.D., professor of radiology; Theodore Lawrence, M.D., Ph.D., Isadore Lampe Professo...

Needling Chromosomes Reveals Cell Division Secret

...s. However, he said, Paliulis masteredthe delicate technique and performed numerous experiments pulling thechromatids apart at different points along their length and atdifferent times during cell division.The experiments revealed that the chromatids are attached to oneanother, but that they initially separate...

ASU researchers finds novel chemistry at work to provide parrot's vibrant red colors

...sampled. The researchers used a chemical analysis technique called high-performance liquid chromatography to survey the pigments present in red parrot feathers. McGraw and Nogare collected and analyzed samples from 44 parrot species that have red feathers. Overall, there are some 350 species of parrots, 80 pe...

Genetically modified natural killer immune cells attack, kill leukemia cells

...St. Jude team were the development of a laboratory technique for rapidly producing a large, pure population of ...lls from a small sample of blood; and developing a technique for genetically modifying NK cells so that they would become potent killers when they encountered le...

Transport System Smuggles Medicines Into Brain

...sampled. The researchers used a chemical analysis technique called high-performance liquid chromatography to survey the pigments present in red parrot feathers. McGraw and Nogare collected and analyzed samples from 44 parrot species that have red feathers. Overall, there are some 350 species of parrots, 80 pe...

Alcohol's effects on gene expression in the central nervous system

... drinking and repeated withdrawals. The microarray technique provides insight into cellular changes that occur over time with chronic alcohol drinking and repeated withdrawals." Collectively speaking, added McBride, findings presented at the symposium demonstrate the quantitative and qualitative applications ...

Nano-Probes Allow an Inside Look at Cell Nuclei

...ey Lab's Life Sciences Division, who developed the technique with Daniele Gerion of Lawrence Livermore National... their mitochondria," says Chen, adding that their technique paves the way for imaging a host of other long-term biological events. "The toughest part is getting...

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