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Tag: "targets" at biology news

Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics

... Though numerous molecules have been identified as targets for use as nano-scale electronic components such as switches, photoelectric devices and hydrogen generators, some major technical problems have stymied further research. The first of these has been the difficulty in making reliable connections with s...

Stealth Worms May Improve Insect Pest Control

...t. Nematodes usually have to be underground; their targets are soil insects." The formulations keep improving as newer isolates of nematodes are found, and there is a lot of commercial interest in matching nematodes to pests, Stock says. "Yet these nematodes are so powerful and pathogenic not in and of the...

Microscopes at microscopic size

...rs to allow the scientists to analyse the cells or targets within the cells. Researchers can use this capability to examine cellular conditions for certain diseases or to develop new treatments by studying the way cells react to a drug. The biochips also raise the possibility of a micro-laboratory, the size...

Newly Discovered 'Branding' Process Helps Immune System Cells Pick Their Fights

...he immune system uses to label foreign invaders as targets to be attacked. Researchers showed that the immune system can brand foreign proteins by chemically modifying their structure, and that these modifications increased the chances that cells known as lymphocytes would recognize the trespassers and attac...

How A Latent Virus Eludes Immune Defenses

... means no red flags for immune cells. If the virus targets one of the many cell types that rarely divide, it’s relatively safe while latent. But some viruses, like the gamma-herpesvirus, infect B cells of the immune system, which occasionally divide. The gamma-herpesvirus genome persists as circular pieces o...

Touching Molecules With Your Bare Hands

... means no red flags for immune cells. If the virus targets one of the many cell types that rarely divide, it’s relatively safe while latent. But some viruses, like the gamma-herpesvirus, infect B cells of the immune system, which occasionally divide. The gamma-herpesvirus genome persists as circular pieces o...

Gov't Creates Gene Database of Normal Human Tissues

...vides a platform that may help scientists find new targets in the cells of previously incurable cancers. The driving force of research in our section is to translate genomic information to the clinic. The goal is to save lives and improve the quality of life for children with high-risk cancer." Until now, n...

NHGRI targets 12 more organisms for genome sequencing

... plan that identified two groups of new sequencing targets on the basis of their collective scientific merits. "Our sequencing strategy continues to focus on identifying the sets of organisms with the greatest potential to fill crucial gaps in biomedical knowledge," said Mark S. Guyer, Ph.D., director of NH...

Remote control flies? Fly behavior controlled by laser light

...ote controls placed in other nerve cells that were targets of the giant fiber system worked 82 percent of the time, the researchers concluded. Lima and Misenböck also equipped another set of nerve cells called dopaminergic neurons with the remote controls, boosting the flies' activity levels and changing the...

Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis

...e first product in early diagnosis and therapeutic targets in hepatic diseases. OWL Genomics is devoted to research into the diagnosis and prevention of liver diseases, through the combination of its state-of-the-art technology and experienced and dedicated personnel. ...

Analysis Of Human Genome To Predict The Development Of Illnesses

...ity, will enable the identification of therapeutic targets for cancer, depression and hepatitis. The School ...erate their diagnosis and identify new therapeutic targets (lines of action) for ailments such as cancer, depression and hepatitis. This bioinformatics tool, ...

DOE JGI launches IMG public online microbial genome data clearinghouse

... sponsored by the DOE Genomics: GTL program, which targets the use of DNA sequences as starting points for systematically tackling questions about the essential processes of living systems. Andersen is exploring the potential of a particular microbe, Caulobacter crescentus, for heavy-metal remediation in was...

Researchers test new therapy for advanced melanoma

...exibility to introduce a huge variety of potential targets for treatment, but its major limitation has been getting the gene into the cancer. If electroporation can deliver the gene to these tumors reliably and without serious side effects, melanoma and other cancers would be open to many new treatment possi...

Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines

...nd develop compounds that act on specific cellular targets has just gained a computational ally ?a mathematic...ways to predict optimal drug design. The molecular targets of many drug candidates are unknown and are often difficult to tease out from among the thousands of...

Researchers reveal secret of key protein in brain and heart function

...le in the body. And that will point drug makers to targets for developing new ways to treat cardiac or neurological diseases. "To arrive at a solution, you need to understand the problem," Mierke said. "Solving protein structures opens doors for effective treatments." SAP97 is found mainly in the central n...

High-powered gene profiles provide clues to genes involved in common form of lung cancer

...iest of all malignancies –?and a range of possible targets for future therapies. The study will be reported ... them to narrow the search for genes that were the targets of the irregular regions. Intriguingly, all of the genes already known to be involved in NSCLC resid...

Critical step traced in anthrax infection

...site for hydrophobic drugs, and it is one of their targets for further investigation. "I believe discovery of the phi-clamp will prove to be one of the high points along the path to understanding how translocation occurs in this system," Collier said. One of the greatest strengths of the experiment, accordi...

Bioinformatics reveals new gene regulation system

...n. So, he said, this work has identified potential targets for designing new antibiotic drugs. But more importantly, the work shows how molecular discoveries of whole regulatory systems can be made through careful analysis of genomes--without ever lifting a pipette, he said. "There are 100 enzymes functioni...

Achilles heel of the herpes virus possibly found

...mmunodeficiency virus (HIV) into cells have become targets for new AIDS drugs. ...

Scripps research scientists identify infertility molecule

...echanisms involving these proteins might make good targets for therapeutic intervention, perhaps even leading...or molecule in the body, and an important class of targets for the design of drugs. Indeed, about half of the medicines on the market target such GPCRs. In th...

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