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Tag: "targeting" at biology news

U-M researchers discover gene switched off in cancer can be turned on

...eptin and Gleevec more effectively treat cancer by targeting genetic mutations that express themselves in large amounts, causing cancer to develop. But cancers also arise because genes that control growth are turned off. While researchers can use these turned-off genes to identify or monitor cancer, currently ...

In mice, drug protects against diabetes and atherosclerosis

...pound. In turn, they add, the results suggest that targeting aP2 "can lead to a new class of powerful therapeutic agents to prevent and treat metabolic diseases such as type 2 diabetes and atherosclerosis." Said Hotamisligil, "This work turned out to be a perfect example of out-of-the box thinking, inter-in...

The insect vector always bites twice

... in transmission areas, the presence of antibodies targeting specifically these proteins contained in an extract of total saliva of the culprit vector. This approach, based on the studies of malaria transmission by mosquitoes of the genus Anopheles and human African trypanosomiasis (sleeping sickness) by G...

Old memory traces in brain may trigger chronic pain

...fied a drug that controls persistent nerve pain by targeting the part of the brain that experiences the emotional suffering of pain. The drug is D-Cycloserine, which has been used to treat phobic behavior over the past decade. In animal studies, D-Cycloserine appeared to significantly diminish the emotion...

Scratch no more: Gene for itch sensation discovered

...very could rapidly lead to new treatments directly targeting itchiness and providing relief for chronic and severe itching. The "itch gene" is GRPR (gastrin-releasing peptide receptor), which codes for a receptor found in a very small population of spinal cord nerve cells where pain and itch signals are trans...

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