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Chemists create 'Superbowl' molecule; May lead to better health

...er market, but any useful application is likely to take five to ten years, the researcher estimates. Administration of the molecule for drug delivery could be by mouth or by injection, he adds. There are hurdles to overcome. The current version of the superbowl molecule lacks solubility in water, which c...

Bioartificial kidney under study at MCG

...e blood. But two-thirds of the study participants take the additional step of having the liquid portion of their filtered blood, called an ultrafiltrate ?which would contain remaining toxins, electrolytes, mediators of inflammation and such ?removed. The liquid is run through the cell-lined fibers of a s...

Man and mouse share genome structures

...mystery of how genes are turned on. The ability to take global views of chromatin in human cells holds tremendous promise for unraveling this mystery." ...

A new mechanism of regulating RNA degradation

...ent for cell biologists and clinicians who want to take control of gene expression in cells to create therapies to treat disease. While cells have a variety of ways to control gene expression, the trick for players in this game is to recognize them amidst the incredibly complex background of cellular mach...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...ent for cell biologists and clinicians who want to take control of gene expression in cells to create therapies to treat disease. While cells have a variety of ways to control gene expression, the trick for players in this game is to recognize them amidst the incredibly complex background of cellular mach...

UAB scientists discover the origin of a mysterious physical force

...h most physical, chemical and biological processes take place. Therefore, it is essential to understand th...olding is essential, since the form these proteins take on when they fold influences how effectively they are able to act. Fully understanding the properti...

Priming embryonic stem cells to fulfill their promise

...em cell niche has been understudied. If we can now take whatwe've learned, add combinations of growth factors, and even add othercells to embryonic stem cells, we may be able for the first time tostudy all the dimensions of the niches required to very specificallycontrol embryonic stem cell differentiatio...

Timing is everything: First step in protein building revealed

...r results support the idea that two separate steps take place oncethe instruction's starting point is found: first a structural change inthe ribosome complex, and then release of eIF1.Lorsch's goal is know the five "Ws" and one "H" that affect timing ofall of the ribosome's pieces and activities. But unra...

UW's Rosetta software to unlock secrets of many human proteins

...ions for agiven protein, collecting the data would take many thousands oflifetimes to complete with conventional computers, said Dr. RichardBonneau, one of the researchers.But by summoning the computing power of millions of volunteers aroundthe world, he said, the task will be completed in less than a yea...

Researchers find how protein allows insects to detect and respond to pheromones

...ions for agiven protein, collecting the data would take many thousands oflifetimes to complete with conventional computers, said Dr. RichardBonneau, one of the researchers.But by summoning the computing power of millions of volunteers aroundthe world, he said, the task will be completed in less than a yea...

Researchers Uncover Key Step In Manufacture of Memory Protein

... known as lipids. If this binding process does not take place, proBDNF cannot be converted to its active form. Dr. Loh explained that the proBDNF molecule has four projections, resembling prongs. These prongs fit into a corresponding indentation on CPE, analogous to the way a plug for an electric applianc...

Plants respond similarly to signals from friends, enemies

...into usable nitrogen for the plant and, in return, take some of the plant's energy to survive. A similar relationship appeared when Weerasinghe studied the signals between plants and nematodes, even though the nematode provides no benefit to its host. Root-knot nematodes form feeding cells ?so-called gian...

Male circumcision reduces risk of HIV transmission from women to men

...tudies, however, the presentstudy was also able to take into account cultural characteristics thatmight be responsible for differences in sexual behavior. Thesedifferences could, in turn, account for differences in the risk ofinfection. But the researchers found that cultural differences insexual behavior...

Computers to be used to find blueprint for new influenza drug

... produced by trial and error in a process that can take many years. Professor Williams and his colleague ...t will then be for the pharmaceutical companies to take our blueprint and turn it into a drug.?/p> Professor Williams said that his work is a more sophi...

New Technique for Tracking Gene Regulators

... time, would be too labor-intensive,expensive, and take a very long time.Scientists have been working on short cuts, but all so far have limits.For example, in one recent technique, scientists mix the regulatorprotein of interest (let’s say, CREB) with the entire genome of a celland let it bind. Then they...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

... There are several specific actions physicians can take to use this new information wisely, Drs. Ackerman and Badley say. The first is to screen by electrocardiogram for heart effects in vulnerable patients. The second is to be alert for multiple drug therapy situations, because certain drug-drug combinat...

The secret lives of whales

...ness in the middle of the ocean basin where echoes take 10 to 20 minutes to return. “They must have the ability to process low-frequency sounds into images just as dolphins do with high frequency sounds, and they must have remarkable acoustic memories just as we have visual memories,?says Clark. Clark co...

Gene therapy converts dead bone graft to new, living tissue

... is why doctors encourage post-menopausal women to take calcium supplements, so that the body doesn't raid their bones for the calcium it needs. The process works both ways, fortunately, as another set of cells, called osteoblasts, rebuilds the bone when the body has excess calcium. In an average year, a ...

Molecular machine may lead to new drugs to combat human diseases

...e professor of biochemistry. Normal genes then can take over without actually changing the genetic code. The results of the Purdue study are published in the January issue of the journal Nature Structural and Molecular Biology. "In terms of human health, Group I introns are interesting because they cau...

Sea skate experiment sheds light on human cell transport

...ally drastic physiological change: Our cells would take in too much water, diluting blood and other body fluids and rapidly causing death. So how do skates do it? Goldstein and Musch learned how cellular channels, or gates, spring into action when skate red blood cells become engorged with water. Vesicle...

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(Date:9/16/2014)... school biology taught us that we inherit certain traits ... you could change how these genes play out by ... diet? That,s exactly what a team of researchers ... proposed through their research of epigenetics research. , ... chemically modifying DNA and histone proteins, which prevent permanent ...
(Date:9/16/2014)... own bacterial identity. That,s the conclusion of University of ... the genetic fingerprints of bacteria on 57 species of ... demonstrates for the first time that host plants from ... very different microbial communities on their leaves," said lead ... the UO,s Institute of Ecology and Evolution who is ...
(Date:9/16/2014)... 10-km diameter chunk of rock hit the Yukatan peninsula near ... force of 100 teratons of TNT. It left a crater ... global earthquakes and volcanism are widely accepted to have wiped ... the mammals. But what happened to the plants on which ... from the University of Arizona reveals that the meteorite impact ...
Breaking Biology News(10 mins):Epigenetic drugs: A hope to treat cancer resistance and reduce cancer relapse? 2Epigenetic drugs: A hope to treat cancer resistance and reduce cancer relapse? 3Microbiome research shows each tree species has a unique bacterial identity 2Meteorite that doomed the dinosaurs helped the forests bloom 2Meteorite that doomed the dinosaurs helped the forests bloom 3
(Date:9/17/2014)... Oxford, UK, September 17, 2014 The International Journal ... has opened up its archive of previously published content: after ... read. A key aim of the IJS is ... hoped that by making these articles available to all will ... Editor-in-Chief of IJS said, "The journal has always ...
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