Virginia Tech group adds tools to DNA-targeted anti-cancer drugs
... the researchers are now able to add a luminescent tag that glows in the presence of ultra violet (UV) li...inecke will present "Using 31P NMR and a phosphine tag to monitor stereochemistry and reactivity of Ru(II) light absorbing units in supramolecular assembli...Scientists take aim at virulent bacteria by decoding machinery of key control enzyme
...ation. Methylation is a biological process used to tag a variety of molecules, including DNA, and is important in cellular processes such as regulating gene expression, DNA replication and repair. In humans DNA methylation occurs on the C (cytosine) rather than the A (adenine) nucleotide. Recently scien...Small worm yields big clue on muscle receptor action
...the synaptic current," said Richmond. "Now we can tag this receptor, see if it's localized at the synapse and start to mutagenize animals to figure out what makes that receptor stay or make it to the synapse," she added. Richmond said the finding might have direct relevance to humans because the ACR-16...50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel
...t, the researchers found, and closed when the SUMO tag is attached. When it is closed, potassium ions build up within the cell. When they reach a threshold level, the cell is primed for activity, such as transmitting a nerve impulse. Sumoylation has recently been recognized as an important mechanism of ...Mayo Clinic Researchers Create 'Obedient Virus'; First Step To Use Measles Virus Against Cancer
... outside of the cancer-seeking measles virus. This tag is the key innovation of their work and central to...e before this specific innovation of the molecular tag -- and research in this area was at an impasse. Not any more. "The virus goes where it's meant to g...UCSD team discovers specialized, rare heart stem cells in newborns
...he UCSD team used sophisticated genetic methods to tag the progenitor cells in living embryonic tissue and in the newborn heart of mice. With these techniques, they were able to show that the isl1+ progenitor cells were spontaneously able to form cardiac muscle tissue. "Furthermore, the cardiac muscle c...The very unexpected life and death of a leukemic cell
...ier" than normal. The special hydrogen serves as a tag that enables researchers to track the utilization of water in the body. The hydrogen incorporates into glucose and the tagged glucose eventually makes its way into the cell's DNA. Researchers gave 19 individuals with CLL a small dose of heavy water ...Newly Discovered Compound Blocks Known Cancer-Causing Protein
...the pathway, the Icmt enzyme. Icmt adds a chemical tag called a "methyl group" to Ras. This methyl tag enables Ras to be directed to its final destination in the cell, from where it can send signals for ...Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
...individual living cells by attaching a fluorescent tag to a specific cell component -- in this case clathrin. "This means that now we could suddenly look at a much broader dynamic range of activity," Dr. Ryan said. "Instead of it being an 'all or nothing' proposition, we were able to understand how chan...