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Tag: "tag" at biology news

Scientists use nanoparticle to discover disease-causing proteins

... called a dendrimer, with a glowing identification tag that was delivered to specific proteins in living venom cells from a rattlesnake. The scientists want to find a better way to ascertain the presence, concentration and function of proteins involved in disease processes. They also hope the new method ...

Lost dogs found more often than lost cats, study suggests

...se the animal wore a dog license or identification tag at the time of its disappearance. "The animal co...an half (48 percent) of dogs had an identification tag or microchip when they went missing. Microchips, which are implanted under the skin, provide permane...

Bumblebee house warming -- it takes a village

...formance, the researchers glued a numbered plastic tag to the thorax of workers in three colonies. They observed and videotaped the incubation and wing fanning, or cooling, performed by individual workers under four temperature conditions ?cold, moderate, warm and hot. Temperatures ranged from 10.3 to ...

'Terror bird' arrived in North America before land bridge, study finds

...Who knew that all these fossils essentially have a tag that says 'hey, I'm from over here!' " ...

Nanoparticles for delivery of prostate cancer treatment

...ectors," said Garen. The nanoparticles will have a tag on their outside that binds to the tumor blood vessels. After binding, they are taken up by the cells and unload the gene that codes for the Icon, allowing the cells to produce and secrete the Icon. "The key is to have an efficient and safe way to...

Living view in animals shows how cells decide to make proteins

...ouse carried in its FGFR2 gene a green fluorescent tag that would glow when a common type of silencer, called an "intronic silencer," chopped out a specific exon, called IIIb. In this way, the scientists could track whether intronic silencers were chopping out the IIIb exon -- and if so, in which tiss...

'Killer' B cells provide new link in the evolution of immunity

...mong other things, the creation of antibodies that tag foreign particles and microbes for destruction. "When examining fish B cells we see them actively attacking and eating foreign bodies, which is a behavior that, according to the current dogma, just shouldn't happen in B cells," said J. Oriol Sunyer...

Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration

...t the University of Michigan Kellogg Eye Center to tag rod precursor cells and prepare them for transplan... research, using an NRL gene regulatory element to tag the rods with a green fluorescent protein. This enabled Kellogg scientists to illuminate the rods, w...

New engineered drug may offer prolonged arthritis relief

...n, thereby restoring its activity. "With the ELP tag gone, you get back your originally active drug," Shamji said. "That finding was pretty unexpected," Setton added. "We hadn't intentionally designed it to have that feature at all." The researchers now plan to work with collaborators to test the m...

Stem cell activity deciphered in the aging brain

...earchers then used another fluorescent molecule to tag all stem cells that were undergoing division in the process of staying "fresh" in case they were recruited to become mature nerve cells. They found that in young rats, approximately 25 percent of the neural stem cells were actively dividing, but on...

Plague proteome reveals proteins linked to infection

...proteomic techniques called accurate mass and time tag mass spectrometry and clustering analysis to compare abundance changes in 992 proteins under four different growth conditions, at 26 degrees and 37 degrees Celsius and with and without calcium. They found 89 candidate proteins with similar abundan...

'Killer' B cells demonstrate evolutionary link between fish and mammal immune systems

...mong other things, the creation of antibodies that tag foreign particles and microbes for destruction. Mammals have phagocytic cells, but they are a specialized few cells identified apart from the complex interactions that drive other white blood cells. Sunyer and his colleagues discovered this previou...

With record resolution and sensitivity, tool images how life organizes in a cell membrane

...ruments of France and housed at LLNL. With a price tag of $3 million, it does a lot more than its cousins common in labs everywhere. It allows scientists to probe the composition of cell membranes with a higher resolution than light microscopy. By providing information about chemical composition of a sam...

Researchers find protein that silences genes

...ly engineered the protein to include a fluorescent tag and found that much of the HDA6, seen as a glowing red signal under the microscope, shows up in the nucleolus, which is precisely the site where ribosomal RNA genes are regulated and where nucleolar dominance occurs. "We found HDA6 at the scene of t...

What's nature worth? New computer models tell all

...all agree it's not worthless. So, what's the price tag on benefits provided by nature? In 1997, the University of Vermont's Robert Costanza and his co-authors put the answer at $33 trillion per year in a now-famous paper in the journal Nature. In the decade following, the science of "ecosystem services...

Study reveals how cells destroy faulty proteins in cystic fibrosis

...ecifically recognize misshaped regions of CFTR and tag them with a degradation signal known as ubiquitin. The ubiquitin tag tells the cell to destroy the marked CFTR, a process overseen by a destroyer called the proteasome. ...

'Sticky' mice lead to discovery of new cause of neurodegenerative disease

...at the cells were making an unsuccessful effort to tag and destroy the accumulating misfolded proteins. "Our finding that this mechanism underlies a neurodegenerative disease was highly unexpected," said Ackerman. "It was perfectly obvious that mischarged tRNAs, may generate misfolded proteins. But wh...

How satellite tracking revealed the migratory mysteries of endangered Atlantic loggerhead turtles

...hat every time the turtle surfaces to breathe, the tag transmits the turtle's position, as well as other information (e.g. depth and duration of dives), to satellites orbiting above, which then relay the data by e-mail to the computer of the scientist who attached the tag. For more information about trac...

MIT 'seeing machine' offers hope to blind

...s about $4,000, low compared to the $100,000 price tag of its inspiration, a machine Goldring discovered through her eye doctor. Goldring's adventures at the intersection of art and high technology began with a visit to her doctor, Lloyd Aiello, head of the Beetham Eye Institute of the Joslin Diabetes C...

Creating a window on 'oceans in motion'

...tion, the Ocean Tracking Network, whose goal is to tag a vast range of ocean animals large and small with...depths and locations. Depending on the variety of tag used, the data is revealed when an animal is recaptured, surfaces (sending the archived data to a sa...

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