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Tag: "tack" at biology news

Poplar trees redirect resources in response to simulated attack

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have applied some of the same techniques used in medical imaging to track the distribution of nutrients in poplar trees in response to a simulated insect attack. The research provides new insights on a long-debated theory about how plants respond to environmental stress, and shows that radiotracer imaging can be a big he...

Genetically modified natural killer immune cells attack, kill leukemia cells

Natural killer (NK) immune system cells can be genetically modified to brandish a powerful "on-switch" that prompts them to aggressively attack and kill leukemic cells. This finding, from researchers at St. Jude Children's Research Hospital, suggests a way to improve the outcome of children who receive treatment for acute lymphoblastic leukemia (ALL) or other blood cancers. .. . The researchers d...

Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks

A Medical College of Wisconsin research team, led by John W. Lough, Ph.D., professor of cell biology, neurobiology and anatomy has found that embryonic stem cells (ES cells) in animals can be cultivated to form new tissue, which eventually may help doctors learn how to replace tissue damaged as a result of a heart attack. .. The potential for ES cells to replace damaged or diseased cells in adult...

Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells

Natural killer (NK) immune system cells can be genetically modified to brandish a powerful "on-switch" that prompts them to aggressively attack and kill leukemic cells. This finding, from researchers at St. Jude Children's Research Hospital, suggests a way to improve the outcome of children who receive treatment for acute lymphoblastic leukemia (ALL) or other blood cancers. . .. The researchers d...

Genetic defects give the immune system the green light to attack the pancreas

Scientists at Joslin Diabetes Center have found genetic regions that, when defective, allow the immune system to attack the pancreas ?the first in a series of mis-steps that lead to type 1 diabetes. Armed with these findings published March 22 in the journal Immunity, the researchers are now trying to hone in on the exact genes involved, in mice and in human patients. . “The significance of this...

Prescription Drug Patches Gaining Ground, Tackling New Therapies

Created as an alternate route of drug administration to improve patient compliance and reduce drug side effects, prescription skin patches are rapidly becoming an important healthcare product category. While quietly gaining market share for the treatment of chronic conditions such as angina, hypertension and HRT, the technology is set to make further inroads as transdermal patches for a host of n...

Columbia study shows widely used artery clearing device does not help patients during heart attack

Interventional cardiologists from Columbia University Medical Center have shown that a commonly used procedure to remove fatty debris from blocked arteries during a heart attack does not improve patient outcomes. .. The procedure, called distal microcirculatory protection, is commonly and successfully used during angioplasty in vein grafts and stenting in carotid arteries. The study, published in...

Shark attack worries? Driving to the beach is more deadly

Which is more likely to happen - you being in a car wreck or being bitten by a shark? .. . .. McEachran goes on to note that far mor...

Stem cell therapy successfully treats heart attack in animals

Final results of a study conducted at Johns Hopkins show that stem cell therapy can be used effectively to treat heart attacks, or myocardial infarction, in pigs. In just two months, stem cells harvested from another pig's bone marrow and injected into the animal's damaged heart restored heart function and repaired damaged heart muscle by 50 percent to 75 percent. . The Hopkins findings, first pr...

New insights into how Huntington's disease attacks the brain

Scientific theory holds that Huntington's disease (HD) is caused by a mutant protein that arises within brain cells and kills them, triggering the genetic neurological disorder. Now a new UCLA Neuropsychiatric Institute study reveals the first strong evidence that the mutant protein also elicits toxic interactions from neighboring cells to provoke the fatal brain disorder. The May 5 edition of Ne...

Attacks of King George III's madness linked to key metabolism molecule

PGC-1 mediates effects of nutrition on blood disease porphyria .. . The mental and physical symptoms of porphyria, a rare genetic blood disease which a number of modern researchers believe plagued King George intermittently throughout his tumultuous reign, can be brought on...

Transgenic goat's milk offers hope for tackling children's intestinal disease

It's hard to improve on milk, but animal scientists at the University of California, Davis, have found that milk produced by transgenic goats, which carry the gene for an antibacterial enzyme found in human breast milk, altered the intestinal bacteria in young goats and pigs that were fed the milk. . The researchers hope these findings will one day lead to milk that protects infants and children...

New Lab Research May Help Those Deafened By Immune System Attack

Our immune system protects us from disease, destroying invading microbes with a swarm of attacking cells. But it can also go haywire for no apparent reason, ganging up on normal tissues in our body and wreaking havoc. . In thousands of people each year, the immune system attacks the inner ear, home to the tiny, delicate structures that allow us to hear. Without warning, in days or weeks, patients...

Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack

When it comes to the deadly skin cancer melanoma, studying functional tissue rather than cell lines may better provide insight into the disease's development, according to new research from a Howard Hughes Medical Institute predoctoral fellow at Stanford University School of Medicine. . Though multiple genetic alterations are associated with melanoma development, scientists have not been able to...

South Africa still debating how to tackle HIV/AIDS when 5 million are infected

A national conference in South Africa was dominated this week by the continuing debate over HIV/AIDS drugs. Health Minister Manto Tshabalala-Msimang repeated yet again that drugs were not the only way to fight HIV/AIDS, and that eating habits were also important. .. . The minister in the past has been nicknamed Dr. Garlic because of some of her...

Researchers propose measures to curb lion attacks in Tanzania

A breakthrough in human stem cell research, producing embryonic-like cells from umbilical cord blood may substantially speed up the development of treatments for life-threatening illnesses, injuries and disabilities. The discovery made during a project undertaken with experts from the University of Texas Medical Branch and the Synthecon Corporation in the United States provides medical researcher...

'License to kill' enables powerful immune attack cells in mice

Scientists have discovered that a group of important immune system cells has a surprising resemblance to cinematic British superspy James Bond: the cells receive a "license" that allows them to unleash their most potent attacks on enemies. . This licensing process apparently helps reduce the chances that the cells will erroneously direct their firepower at the body's own tissues, according to res...

Bone marrow stem cells may heal hearts even years after heart attacks

Left ventricular function and exercise capacity increased, while the area of heart muscle damage shrank, in 18 patients given infusions of their own bone marrow stem cells up to eight years after a heart attack, according to a new study in the Nov. 1, 2005, issue of the Journal of the American College of Cardiology. . "This new therapy is able to treat until now irreversible heart complaints and...

New factor implicated in allergy and asthma attacks

For a person with allergies or asthma, breathing in pollen can be a very bad thing. Within minutes of inhalation by someone sensitive to their effects, these tiny particles can trigger severe inflammation of the respiratory passages, producing uncontrollable sneezing, coughing, or extreme shortness of breath -- symptoms agonizingly familiar to those who suffer from allergy and asthma attacks. . S...

Researchers Find Drug May Give Some Cardiac Protection 24 Hours After Heart Attack

A drug has been shown to provide some protection to the heart from injury even if given as much as 24 hours after a heart attack, Jefferson Medical College researchers report. . Walter Koch, Ph.D., director of the Center for Translational Medicine in the Department of Medicine at Jefferson Medical College of Thomas Jefferson University in Philadelphia, and his co-workers knew that the drug Darbep...

Many needles, many haystacks

Most of what happens in cells is the work of machines that contain dozens of molecules, chiefly proteins. With the completion of human and other genomes, researchers now have a nearly complete "parts list" of such machines; what's lacking now is the manual telling where all the pieces go. A new study by scientists at the European Molecular Biology Laboratory (EMBL) promises to answer this questio...

Stem cell mobilization therapy appears to be ineffective in repairing damage caused by heart attack

Therapy that involved bone marrow stem cells did not improve cardiac function in patients following a heart attack, according to a study in the March 1 issue of JAMA. . .. Dietlind Zohlnhöfer, M...

New drug could reduce tissue damage after heart attack

A study led by UCL (University College London) scientists has designed a new drug that inhibits the adverse effects of C reactive protein (CRP), a protein that contributes to tissue damage in heart attacks and strokes. The findings, published in the journal Nature, suggest that targeting CRP may produce both immediate and long-term clinical benefits following a heart attack. . CRP is normally pr...

Cancer cells suppress large regions of DNA by a reversible process that can be tackled

Cancer researchers at Sydney's Garvan Institute, in collaboration with Spanish scientists, have formulated a new concept for how cancer cells can escape normal growth controls, which may have far-reaching implications for the new generation of cancer therapies. . .. Our cells become cancerous when the normal contr...

Stem cell study for patients with heart attack damage seeks to regenerate heart muscle

Rush cardiologists are hoping that transplanted stem cells can regenerate damaged heart muscle in those who experience a first heart attack. The study involves an intravenous infusion of adult mesenchymal stem cells from healthy donor bone marrow that might possibly reverse damage to heart tissue. . .. "A person who h...

World shark attacks dipped in 2005, part of long-term trend

Assertive and even aggressive human behavior could explain why shark attacks worldwide dipped last year, continuing a five-year downward trend in close encounters with the oceanic predators, new University of Florida research suggests. . .. In contrast, there were...

One in 14 men having a heart attack drive themselves to hospital

Seven per cent of men having a heart attack drove themselves to hospital and only 60 per cent went by ambulance, according to research published in the latest Journal of Advanced Nursing. . .. "Driving during a heart attack is obviously extremely dangerous for both the dr...

Molecular force field helps cancer cells defend against attack

Much as the famed starship Enterprise would deploy a deflector shield to evade enemy attack, tumor cells are capable of switching on a molecular force field of their own to fend off treatments aimed at killing them. Now University of Florida researchers have found a chink in their armor. . The cells churn out an enzyme that bonds with a protein, creating a protective barrier that deflects damage...

HIV vaccine takes different tack to boosting immune response

Researchers at Baylor College of Medicine (BCM) in Houston have reason to believe their unorthodox vaccine could one day help to prevent or control HIV infection, according to a study published in today's edition of Public Library of Science Medicine. . .. "A lot of vaccines work very well in dealing with some pathogens, bu...

Use of amino acid supplement following a heart attack provides no benefit, may be harmful

Use of the amino acid supplement L-arginine following a heart attack does not improve certain cardiac functions and measurements and may be associated with an increased risk of death, according to a study in the January 4 issue of JAMA. . .. Steven P. Schulman, M.D., o...

Attacking cancer's sweet tooth is effective strategy against tumors

An ancient avenue for producing cellular energy, the glycolytic pathway, could provide a surprisingly rich target for anti-cancer therapies. . A team of Harvard Medical School (HMS) researchers knocked down one of the pathway's enzymes, LDHA, in a variety of fast-growing breast cancer cells, effectively shutting down glycolysis, and implanted the cells in mice. Control animals carrying tumor cel...

Smooth sailing: 'cruise ship virus' tackled by UH, Baylor College of Medicine

You're on vacation, having fun sailing the seven seas, when your stomach starts rolling worse than the waves. Before you know it, nausea and vomiting have replaced shuffle board and sun-bathing. . Unfortunately, it's a scenario that's becoming increasingly common on cruise ships. So common, in fact, that the National Institutes of Health's Western Regional Center of Excellence (RCE) for Biod...

Tumor wizardry wards off attacks from the immune system

Like the fictional wizard Harry Potter, some cancerous tumors seem capable of wrapping themselves in an invisibility cloak. Researchers at Washington University School of Medicine in St. Louis have found that pancreatic tumors hide from the body's immune surveillance by surrounding themselves with cells that make it hard for the immune system to detect them. . The tumor-protecting cells are white...

Researchers attack tumor cells by exploiting dependency on sugar metabolism

Although scientists have known for nearly 90 years that cancer cells commonly display altered sugar metabolism, the molecular significance of this phenomenon is not completely understood. Now, a new study published in the June issue of Cancer Cell reveals a functional connection between carbohydrate-driven energy production and tumor maintenance. Importantly, the results suggest that inhibition o...

Gene discovery opens door to tackling disease

Western Australian researchers have discovered a new gene that could lead to breakthroughs in breast and prostate cancer, as well as diabetes. . .. "When we baited our hook and went fishing in the breast cancer gene library we came up with SLIRP, much to our surprise, as this gene had not been characterised during...

Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer

Mayo Clinic Cancer Center has opened a new clinical study using a vaccine strain of the measles virus to attack recurrent glioblastoma multiforme, a largely untreatable brain tumor. This is the second of several pending molecular medicine studies in patients using measles to kill cancer. . "We are looking at better ways to treat some of the most lethal cancers," says Eva Galanis, M.D., oncologis...

Fire ant-attacking fly spreading rapidly in Texas

Parasitic flies introduced to control red imported fire ants have spread over four million acres in central and southeast Texas since the flies' introduction in 1999, researchers at The University of Texas at Austin have discovered using new flytraps they developed. . .. Dr. Ed LeBrun, a researcher at BFL, developed the new fly...

Solved: The mystery of flesh-eating bacteria's relentless attack

A Howard Hughes Medical Institute (HHMI) international research scholar in Israel has discovered one reason why so-called "flesh-eating" bacteria are so hard to stop. . Emanuel Hanski, a microbiologist at Hebrew University in Jerusalem, and colleagues have found that the success of Group A Streptococcus is due in part to a protein that blocks the immune system's distress calls. The findings, pu...

Scientists work to identify genes that contribute to early heart attack risk

Scientists at Wake Forest University Baptist Medical Center and colleagues at four other medical centers have launched a $10 million multi-year study to identify genes that may contribute to early atherosclerosis. . .. Other participating centers are Cedars Sinai Medica...

Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack

Mass vaccination would not be necessary in the event of a large-scale smallpox bioterrorist attack in the United States, according to a study led by researchers at Fred Hutchinson Cancer Research Center that appears online in the International Journal of Infectious Diseases. . Instead, the current U.S. government policy of post-release surveillance, prompt containment of victims and vaccination o...
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