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Tag: "systems" at biology news

Study of protein folds offers insight into metabolic evolution

...and we are applying it to a biochemical problem, a systems biology problem." To get at the roots of protein evolution, the researchers examined metabolic proteins at the level of their component structures: easily recognizable folds in the proteins that have known enzymatic activities. These protein domai...

Proteasome activator enhances survival of Huntington's disease neuronal model cells

...ins. To accomplish that, a number of intracellular systems work in concert to keep the cell healthy and from clogging up with damaged proteins. When proteins or peptides mutate, they can present major problems to the clearing up of the intracellular environment. In Huntington's disease (HD) the disease provo...

Man's best friend lends insight into human evolution

...ve social problems may have emerged once the brain systems mediating fear were altered ?and the same thing may have occurred in human evolution. Chimps, he says, are constrained in solving cooperative problems by their impulse to fear more dominant individuals and behave aggressively toward more subordinate ...

UCLA study uncovers clues for why Graves' disease attacks the eyes

... Earlier research found that GD patients?immune systems produce an antibody that other people do not. Not recognizing the patient’s thyroid as "self," the antibody mistakenly mounts an attack against the organ, causing inflammation and damage to the body, including eye tissue. In the current study, UC...

MIT's ocean model captures diversity of underwater forests

...ss-disciplinary research project at MIT connecting systems biology, microbial ecology, global biogeochemical ... of phytoplankton, they did not well represent the systems they modeled. The new model remedies that. "Now we are finally modeling the ocean systems in a w...

Noise echoes in cell communications

...anaged by Rutgers-Camden, will further advance the systems biology discipline in South Jersey. ...

In obesity, brain becomes 'unaware' of fat

...major effect on obesity, noting that the digestive systems of mice and humans differ substantially. His team ...se effects in overweight primates, whose digestive systems have much more in common with people. The findings do “strongly support the case?that leptin resi...

Researchers design pulsed mircrojet system to deliver protein drugs without pain or bruising

...pain or bruising that deeper penetration injection systems cause. The research was published online today in .... The effort to create needle-free drug delivery systems is driven by a combination of factors, including needle phobia, pain and discomfort, infections, and...

Penn researchers show how nanocylinders deliver medicine better than nanospheres

...me viruses are so effective. "Cylindrical delivery systems exist in nature, with two prime examples being the Ebola virus and the H5N1 Influenza virus," says Discher. "These findings can help us understand how this shape evolved in nature and the advantages of using it for treating people." ...

Type of stem cell found to reside in transplanted lungs

...ng ?something that might hold true for other organ systems as well. "Potentially the most important outcome of our finding is that it could lead to an understanding about therapeutic options using MSCs that reside in adult organs," Lama continues. "These lung-derived cells are different from MSCs derived ...

Bypassing eggs, flu vaccine grown in insect cells shows promise

...ow as you want in eggs.? The use of cell culture systems to grow vaccines ?using viruses as tiny factories to churn out mass amounts of vaccines ?is a growing business. A similar technology using human cell lines is used to produce the hepatitis B vaccine, while one form of a vaccine against human papillom...

Scientists learn the origin of rogue B cells

... animals. "Most of what scientists do is to create systems to visualize complex phenomena, then to allow nature to give you the answers to your questions," says Casellas. Their new findings raise the question of how this knowledge might eventually help people with autoimmune disease. That question, says C...

Scientists uncover link between ocean's chemical processes and microscopic floating plants

...ill lead to a better understanding of the feedback systems between the atmosphere and ocean, believes Wingenter. "To predict future climate more accurately, it's critical that we understand the outcome of increasing ocean acidification and increasing carbon dioxide levels." ...

Mimicking how the brain recognizes street scenes

...ical model was surprisingly versatile. Traditional systems are engineered for specific object classes. For instance, systems engineered to detect faces or recognize textures are poor at detecting cars. In the biological mode...

Female Antarctic seals give cold shoulder to local males

...bridge, said: "Many mammalian species have mating systems that were traditionally viewed as being dominated by males fighting with each other for the right to mate with passive females. So it's not only remarkable to uncover active female choice in such a system, but this also suggests that female choice m...

Common gene version optimizes thinking -- but with a possible downside

...treams of information from multiple brain chemical systems for processing by the cortex. Both the neurotransmitter that it works through, dopamine, and the chromosomal site of its gene have been implicated in schizophrenia. "Although several groups have looked for possible clinical relevance of DARPP-32,...

Progress toward artificial photosynthesis?

...like layers. The individual layers consist of ring systems involving carbon and nitrogen atoms. This porous material, called graphitic carbon nitride, is very heat-stable and, although it enters into many chemical interactions, it is so stable that it nearly always re-forms—an ideal catalyst. It can even be ...

Penn study on olfactory nerve cells shows why we smell better when we sniff

Unlike most of our sensory systems that detect only one type of stimuli, our sense of smell works double duty, detecting both chemical and mechanical stimuli to improve how we smell, according to University of Pennsylvania School of Medicine researchers in the March issue of Nature Ne...

Keeping the body in sync -- The stability of cellular clocks

...ity of Geneva, the researchers turned to dynamical systems theory and developed a mathematical model that ide...bioluminescence recordings,?explains Felix Naef, a systems biology professor at EPFL and the Swiss Institute for Experimental Cancer Research. “We found that t...

New cell type identified in cancer development

..., a second group was composed of mice whose immune systems had been knocked out by radiation, but had been partially restored by an infusion of bone marrow cells; and the third group was made up of normal, healthy mice. The results showed that the strength of the immune system affected whether or not the ...

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