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Tag: "system" at biology news

Researchers discover new details about HIV-1 entry and infection

...n the McElrath laboratory developed a unique model system to study the precise mechanisms by which HIV-1 enters the lower reproductive tract of human females. The researchers separated and removed the outer lining of vaginal cells, which serves as the first barrier to the virus. The isolated preparation of ...

Molecular signature may identify cisplatin-sensitive breast tumors

...ypes of breast cancers. Using an RNA interference system to inhibit the action of p63, they showed that the protein stimulates tumor growth by interfering with p73’s normal ability to induce cell death. Cisplatin was found to break up the binding of p63 to p73 and reactivate the cell-death process. "The...

Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

...established, Lu says. The nanoparticle delivery system consists of a plasmid gene expression cassette loaded with DNA that encodes the FUS1 protein. This is wrapped tightly in a form of cholesterol to protect it from the body's defense mechanisms. The nanoparticles accumulate mainly in the lungs, part...

Computer scientists join in search for ivory-billed woodpecker

...e skies near Brinkley, Ark., for birds. "If the system can catch any kind of bird, that's a success for us," Song said. "But if it catches an ivory-bill, that's a bonus." With a grant from the National Science Foundation, Song and Goldberg programmed ACONE to distinguish birds from other objects and o...

Researchers discover surprising drug that blocks malaria

...laria marauders hack into the red cell's signaling system and steal the molecular equivalent of its password to spring open the door to the cell. But researchers have found that a common blood pressure medication ?propranolol ?jams the signal to prevent the parasite from breaking in. Scientists had lo...

Penn researchers replace organ in adult mice using 'single-parent' stem cells

... functionally replenish the entire blood-producing system of adult mice. The scientists were able to maintain animals for more than 12 months with entirely uniparental blood and were able to rescue other irradiated mice with bone marrow transplants from these animals. It is clear proof, according to ...

Lab research may one day lead to cancer treatment using patient's own immune cells

...odstream of the same patient to train their immune system to fight the cancer. According to Kim, the Phase I study would involve about 20 patients and would open in about five years. "If these trials prove successful, a similar approach could be developed in patients with other types of cancer as well," ...

Scientists unlock secret of what makes plants flower

...ance signal to travel through the plant's vascular system from the leaf to the shoot apex, where flowering i...(FT gene). It travels through the plant's vascular system to the shoot apex, where it activates other genes, causing the plant to flower. The research team we...

Flavanols in cocoa may offer benefits to the brain

...tric oxide, a critical molecule in the circulatory system that helps dilate blood vessels and keeps them pliable. Hollenberg fed flavanol-rich cocoa to healthy volunteers who were over age 50 and observed a “striking blood flow response?that evolved over several weeks. “Since this cocoa preparation is so...

Study uncovers a lethal secret of 1918 influenza virus

...tion and instead unleashes an attack by the immune system on the lungs. As immune cells attack the respiratory system, the lungs fill with fluid and victims, in essence, drown. The mechanisms that contribute to the lethality of the virus were uncovered by University of Washington researchers using functiona...

The origin of the brain lies in a worm

The rise of the central nervous system (CNS) in animal evolution has puzzled scientists f... Heidelberg now reveal that the vertebrate nervous system is probably much older than expected. The study, which is published in the current issue of Cell, su...

Parasite infection may benefit MS patients

... in order to identify which molecules cause immune system effects that dampen the inflammatory reactions normally seen in autoimmune diseases, the authors note. They conclude that "induction of a regulatory anti-inflammatory network generated by persistent parasite infections may offer a potential explanati...

Health Canada approves cold and flu medicine

...toms. The COLD-fX strategy is to boost your immune system to help you avoid getting a cold or the flu in the first place, or if you do get one, to fight it more effectively." The NHPD’s safety review confirmed the safety profile of COLD-fX with no known side effects or drug interactions for generally hea...

New sensor detects gaseous chemical weapon surrogates in 45 seconds

...ponents exist and initial testing is complete, the system still must be converted to a prototype. ...

Scientists unlock mystery of embryonic stem cell signaling pathway

...e confirmed that IQ-1 plays a similar role in that system as well. “If we can create a totally chemically defined system for growing human embryonic stem cells without any risk of contamination, it would make life much ea...

Antibody signal may redirect inflammation to fuel cancer

...cells of the so-called adaptive or acquired immune system are activated following a bacterial infection and in response, produce antibodies that signal leukocytes to attack," said Coussens, associate professor of pathology in the UCSF Cancer Research Institute. "But in precancerous tissue in mice, we have f...

Can engineered immune cells stop AIDS?

... vexing problem: developing an efficient transport system that is capable of delivering therapeutic payloads...we are experimenting with a way to help the immune system produce antibodies that can neutralize the virus," says Wang. "If we can design a modified virus tha...

Conceptualizing a cyborg

...ical interface that could link a patient's nervous system to a thought-driven artificial limb. Their concept... for Brain Injury and Repair at Penn. "The nervous system will certainly rebel if you place hard or sharp electrodes into it to record signals. However, the n...

Experimental vaccine given during pregnancy reduces stillbirths from common virus

...he viral protein. Cells of the guinea pigs?immune system detect the viral protein and launch an attack against it. In so doing, they learn to recognize CMV. The gene used in the experimental guinea pig CMV vaccine—UL83, also called pp65—contains the information needed to make a protein involved in the in...

Do you hear what i see?

...resent study clearly shows where in the auditory system researchers have to focus." ...

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