Small molecule dervived from Rb2/p130 could act as cancer therapeutic
...e, which they named Spa310. The molecule that was synthetically produced in the laboratory was introduced into mice that had been injected with tumor cells. "Tumor growth was inhibited and the tumors began to reduce in size until they disappeared," Giordano said. Giordano said because of the intrinsic natur...Can engineered immune cells stop AIDS?
... Faced with such a clever adversary, Wang wants to synthetically alter the HIV invaders and use their hollow shells as delivery vehicles to insert DNA that will counteract the infection. The "Cadillac" of this gene delivery system is an HIV-based "lentiviral vector," a type of retrovirus that uses the back...Bacteria could make new library of cancer drugs that are too complex to create artificially
...ial anti-cancer drugs that are difficult to create synthetically on a lab bench. The bacterium Streptomyces coelic... cancer tools, but they cannot currently be easily synthetically produced on a lab bench. Professor Greg Challis and colleagues in the Chemistry Department of the...Heparin prepared synthetically could replace animal-derived drug
... of heparin are estimated at $3 billion. "We have synthetically prepared heparin in quantities large enough for use in human medical treatments by engineering recently discovered heparin biosynthetic enzymes," says Robert Linhardt, the Ann and John H. Broadbent Jr. '59 Senior Constellation Professor of Biocatalys...