Molecular miners find pain relief drugs from the sea
... the DNA sequence. The peptide was then chemically synthesised in large quantities suitable for biological testing. This same approach is now being used by Metabolic Pharmaceuticals to synthesise gram amounts of ACV1 needed for the planned human clinical trials for diabetic neuropathy. "With an increasing age d...Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates
...available today. As the initial step, researchers synthesised nanoparticles for controlled drug release made from a biocompatible and biodegradable PLA polymer system and encapsulated a fluorescently labeled model drug within them, in order to visualise nanoparticle uptake into target cells. The nanoparticles i...Researchers use 'trickery' to create immune response against melanoma
...available today. As the initial step, researchers synthesised nanoparticles for controlled drug release made from a biocompatible and biodegradable PLA polymer system and encapsulated a fluorescently labeled model drug within them, in order to visualise nanoparticle uptake into target cells. The nanoparticles i...Injection may prevent infertility in men receiving cancer chemotherapy
... non-toxic immunomodulatory compound developed and synthesised by us. Tellurium is a transition element with similar properties to Selenium, which is also known to have many beneficial effects." Knowing that AS101 had been shown to have chemoprotective effects in both animal and human studies, he and his team ...Scientists discover way to block growth of prostate cancer cells
...ators at Wayne State University, Detroit, MI, USA, synthesised a molecule called MDL 72,527 (MDL), which was previously known to be an inhibitor of acetyl polyamine oxidase (APAO). APAO catalyses the oxidation of acetyl polyamines produced by SSAT ?the process that results in the generation of ROS. MDL can, th...Genetically engineered blood protein can be used to split water into oxygen and hydrogen
...an, in collaboration with Imperial College London, synthesised a large molecular complex from albumin, a protein molecule that is found at high levels in blood serum, and porphyrin, a molecule which is used to carry oxygen around the body and gives blood its deep red colour. Porphyrin molecules are normally foun...