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Tag: "syndromes" at biology news

Loss of stem cells correlates with premature aging in animal study

...he aging and oncology fields since premature aging syndromes and many cancers involve the loss of DNA repair genes.” When the researchers deleted ATR in the tissues of adult mice, they noticed that the mice showed signs of premature aging, such as hair graying, hair loss, and osteoporosis, within three to f...

Researchers discover 'acquired' DNA key to certain bacterial infection

...swallowed. Incidence of M. avium as a cause of syndromes may be decreasing because of changes in treatment for HIV-infected patients, according to the Centers for Disease Control and Prevention, which estimates that 1 out of 100,000 persons may be affected. However, CDC also notes that the bacterium’s resi...

Microbes start immune response by sneaking inside cells

...licated in the development of several inflammatory syndromes characterized by recurrent fever, skin rash and arthritis. Cryopyrin triggers a key enzyme involved in the body’s inflammatory response, capsase-1, which in turn causes production of IL-1beta, a powerful molecule which signals the immune system t...

Angelman syndrome deficits rescued in mice

... Weeber said, to other types of mental retardation syndromes that remained unexplained and untreatable. "There are a lot of mental retardation syndromes that we still don't understand. Maybe the changes in CaMKII associated with Angelman syndrome could ...

How genetic malfunction causes a form of retardation

...der. Such a mechanism may well generalize to other syndromes where signaling pathways that are important for neural cell genesis are genetically perturbed.? The researchers speculated that “genetic perturbations such as those seen in NS, or perhaps even in more commonly studied disorders such as Rett Syndrom...

'GreeneChip' -- New diagnostic tool that rapidly and accurately identifies multiple pathogens

... be prepared for the unexpected. "Because clinical syndromes are rarely specific for single pathogens, methods that simultaneously screen for multiple agents are important, particularly when early accurate diagnosis can alter treatment or assist in containment of an outbreak," stated W. Ian Lipkin, MD, directo...

New tool helps blood specialists improve patient care

...rtant in the care of patients with myelodysplastic syndromes (MDS). "The hematologists who use these measures are not passive learners. They are not simply reading about how to improve patient care ?they will be doing it," said Steven Allen, MD, a member of the ASH Committee on Practice, which is developing ...

Cellular traffic backups implicated in skeletal malformations

...letal deformities ?one of the most prominent human syndromes ?had ever been linked to that pathway," Knapik said. "I'm very excited that now we have an animal model to study." ...

How IVF could be causing genetic errors in embryos

...ors that are associated with certain developmental syndromes and other abnormalities in growth and development,...echniques. Cases of Angelman and Beckwith Wiedeman syndromes in humans, which are due to aberrant genomic imprinting, and other abnormalities in growth and devel...

Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor

...e in the development of Kaposi's sarcoma and other syndromes associated with the virus. The natural function of xCT in the body is to transport molecules necessary for protecting against stress into cells. When cells are stressed, they express more xCT on their surfaces. Of note, this sort of stress can be ca...

Protein amplification in melanoma is possible drug target

...many cases of immune deficiency, in particular two syndromes known as immunoglobulin A (IgA) deficiency and Common Variable Immunodeficiency (CVID), report researchers in the July issue of Nature Genetics. The discovery may lead to a new diagnostic test for these conditions, which make people highly susceptibl...

Gene for immune deficiency syndromes found

...many cases of immune deficiency, in particular two syndromes known as immunoglobulin A (IgA) deficiency and Common Variable Immunodeficiency (CVID), report researchers in the July issue of Nature Genetics. The discovery may lead to a new diagnostic test for these conditions, which make people highly susceptibl...

Yeast Network Prevents Damage By Oxygen Radicals

...ancer prevalence linked to inflammation-associated syndromes and a variety of human diseases. Now scientists at the University of California, San Diego Branch of the Ludwig Institute for Cancer Research (LICR) have identified a key network of DNA repair and cell cycle control genes in yeast that prevents the d...

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