Brain enzyme treatment relieves memory lapse in Alzheimer's mice
...rain regions in the role of Uch-L1. In mice with symptoms that mimic those found in patients with Alzheimer's disease, treatments that raised Uch-L1 greatly increased their freezing time compared to their transgenic littermates when contextual learning was assessed over time, the researchers found. Improvem...Parkinson's disease mechanism discovered
...ain dopamine levels, causing the tremors and other symptoms of Parkinson's disease. Dopamine is one of many ty...o restore dopamine levels in the brain or to treat symptoms of the disease. Lindquist cautioned that the findings "have not by any means proven that this mecha...Device effective in zapping the pain out of migraines
...or confusion. What typically follows these initial symptoms is intense throbbing head pain, nausea and vomiting. Yousef Mohammad, a neurologist at OSU Medical Center who presented the results, says that the patients in this study reported a significant reduction in nausea, noise and light sensitivity post t...Survivors of childhood polio do well decades later as they age
.... Each patient also completed questionnaires about symptoms of progressive weakness at the beginning and end o... weakness during the time they were studied, these symptoms did not correspond with their actual magnitudes of decline over time. Rather, the researchers found ...Novel therapy combinations gain ground in treating hepatitis
...erapies are making significant progress to improve symptoms of the disease. DDW is the largest international ...tract S1060] In chronic diseases like hepatitis, symptoms have a tendency to fluctuate in severity. As a result, researchers are finding that the diseases ma...Protein connections: A network to understand disease
...hat make you susceptible to a disease or cause the symptoms of it." "Instead of thinking one gene-one disease, you realize that if there are 10 genes that cause the same symptoms, they must do it through some common pathways or interactions with other proteins." In applying the network theory to understandi...Finding paves way for better treatment of autoimmune disease
...y cells. Regulatory T cell therapy also resolved symptoms in a model of graft versus host disease, a problem for some bone marrow transplant patients when immune cells from the donor start attacking. This finding indicates a potential role for helping transplant patients keep new organs, the researchers say...Natural pine bark extract relieves muscle cramp and pain in athletes and diabetics
...ur weeks. After the treatment phase, participants' symptoms and cramping episodes were recorded for one week w... to involve muscle damage which may be followed by symptoms of inflammation. In separate studies published this year and in 2004 and 2005, Pycnogenol demonstrat...HIV-1's high virulence might be an accident of evolution
...nfected nonhuman primates usually don't suffer the symptoms associated with AIDS. The evidence now revealed by... that found that nef-deficient SIV failed to cause symptoms in a monkey species normally susceptible to disease, Kirchhoff said. Rhesus macaques infected with t...Allergy battle could be won in five years, says scientist
... If successful, the drug would treat established symptoms already found in adult sufferers and, in due cours...e allergen at this early stage ?they only ease the symptoms ?so the development of these ADIs would be a major breakthrough in our fight against allergies." ...Study shows pine bark naturally decreases severe chronic venous insufficiency
...nt. A composite, analogue score based on signs and symptoms (edema, pain, restless limbs, subjective swelling,...efficacy and safety in several clinical trials and symptoms of CVI have been reduced significantly by Pycnogenol® in controlled studies. We were pleased to see ...Gene therapy injected into the brains' of mice with Huntington's disease
...opping the disease process in its tracks, delaying symptoms from ever showing up." Huntington's disease is an...to have the genetics of HD. The HD mice exhibited symptoms of motor deficits including loss of control, gait abnormalities, hypokinesia (abnormally decreased m...... that Prozac (fluoxetine) is likely to relieve the symptoms of depression by somehow causing more neurons to be present in a particular region of the brain (the "dentate gyrus"). But the origins of these neurons, and how Prozac promotes their existence, have been a mystery until now. By profiling the telltal...Movie spies on malaria parasite's sneaky behavior
...is stage of the parasite's life cycle, the classic symptoms of malaria ?high fevers and chills ?are triggered ...lls. The rupturing of blood cells causes the worst symptoms of the infection, which can be deadly to children, pregnant women, and others with weak immune syste...A sweet solution for Alzheimer's disease?
... with scyllo-inositol, all of the animals' disease symptoms improved. Cognitive function was improved, amyloid...nly transiently and only when given before disease symptoms appeared. Scyllo-inositol "is an exciting experimental therapy, but until it has actually been tes...Researchers attack tumor cells by exploiting dependency on sugar metabolism
...ete hereditary deficiency of LDH-A do not show any symptoms under ordinary circumstances, the genetic data suggest that inhibition of LDH-A activity may represent a relatively nontoxic approach to interfere with tumor growth," explains Dr. Fantin. ...Prion find points way to test for human 'mad cow' disease
... months before the hamsters began showing clinical symptoms of the disease, the Science paper reports. To detect the very small quantities of prions found in blood samples, UTMB professor Claudio Soto, assistant professor Joaquin Castilla and research assistant Paula Saá used a technique known as protein mis...Mechanism for neurodenegerative diseases linked to transport proteins
...expansion or "polyQ" diseases are characterized by symptoms that begin in middle age and by the loss of certain types of neurons through a pattern in which the neuron's terminals die before the cell body. PolyQ genes are expressed in many types of cells, but only neurons are affected. Earlier studies had lin...Reversing 'hibernating' heart muscle focus of UB researchers
...to new therapies that will improve the outlook and symptoms of these patients who are at high risk for adverse cardiovascular events," said Canty. Additional investigators on the study are Alan D. Hutson, Ph.D., professor and chair of the UB Department of Biostatistics; Te-Chung Lee, Ph.D., associate profes...Dopamine drug leads to new neurons and recovery of function in rat model of Parkinson's
...ra. While many drugs are available to treat these symptoms during the early stages of the disease, the treatm... rats with neuron loss in the substantia nigra and symptoms similar to human PD on one side of the body. 7-OH-DPAT is not used in humans, but its effects on do...