Scientists reveal molecular secrets of the malaria parasite
...hemosquito. That motif regulates proteins that are switched on as theparasite enters the mosquito.Hall's group identified the gene regulation by comparing the genesexpressed in the sexual stage transcriptome with the proteomes of boththe sexual stage and a developmental stage in the mosquito. Severalgenes wer......igned mines for the British navy. After the war he switched from physics to molecular biology, and, with a Medical Research Council fellowship, he went to Cambridge University. There he joined Max Perutz’s protein structure group at the Cavendish Laboratory and earned his Ph.D. in 1953. In the summer of 1951...Highly adaptable genome in gut bacterium key to intestinal health
...ivity analysis showed that B. theta had adaptively switched on a different set of genes encoding surface proteins and carbohydrate-busting enzymes. This switch allowed B. theta to bind to and digest the host-produced mucus carbohydrates. "By changing its digestive enzymes and surface proteins, the bacterium ...Open microfluidic and nanofluidic systems
...rfaces covered by molecular monolayers that can be switched by light, temperature, or electric potential. The experiments described in the PNAS study use a polymeric liquid that freezes quickly and can then be scanned directly with the tip of an atomic force microsope. However, the same morphology diagram sh...Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
... and previously unknown specifics of how genes get switched on during development of the human body and in diseases such as cancer. "Each type of cell in our bodies contains the same genes. What makes them do different things involves which genes are turned on," notes Bradley Bernstein, a pathologist at Harv...Researchers identify target for cancer drugs
...ancers. If Akt travels to the cell membrane, it is switched on and promotes cell division, often contributing to tumor growth as a result. However, as long as it stays within the cell cytoplasm, it remains relatively inactive. That's because the tumor-suppressor protein PTEN keeps Akt in check by destroying l......ocks into small blocks and found that the termites switched their preference to the large blocks. Prof Lai created an artificial signal similar to that made by the termites chewing the large block, which Dr Evans broadcast into small blocks and the scientists found that the termites had no preference for eith...