Immune cell communication key to hunting viruses, Jefferson immunologists show
.... "That's the power of killer cells. "We always suspected that recognition of other peptide MHCs, like self-peptide MHCs derived from normal proteins, could facilitate recognition, but it was not clear until now how this happened." Dr. Sykulev notes that this finding is not only relevant to viral infected c...3-D ultrasound scanner could guide robotic surgeries
... organs captured prior to biopsy to locate lesions suspected to be cancer. As artificial intelligence technology improves in the coming decades, the scanner might even be able to guide surgical robots without the help of a surgeon, the researchers said. The 3-D ultrasound probe has yet to be tested in huma...Epstein-Barr virus might kick-start multiple sclerosis
... and may contribute to some cancers, has long been suspected to play a role in MS. However, the mechanism linking the virus to the disease was poorly understood. Scientists think that MS--which can cause vision problems, muscle weakness, and difficulty with coordination and balance--is a result of the immune...How bad is malaria anemia? It may depend on your genes
...stands for migration inhibitory factor), were long suspected to cause malarial anemia because they are known to reduce red blood cell counts as part of the body's normal response to such inflammatory conditions as rheumatoid arthritis or some cancers. Using immature blood cell precursors grown in a dish, the ...Scientists identify protein with a crucial role in cell death
...le for. Given this vital function, scientists have suspected that the inner workings of a cell depend largely o... the mitochondria function. Therefore, it has been suspected that poorly functioning mitochondria can, among other things, lead to a disturbance in brain cells a...'Pinball protons' created by ultraviolet rays and other causes can lead to DNA damage
...ld simply pull apart." Though it has already been suspected that lesions in DNA caused by both high- and low-energy electrons result in cancer cell formation, the new study is the first evidence that protons do the same thing. The study in PNAS also has other implications. Researchers are beginning to unders...New light microscope sharpens scientists' focus
...cept struck them as so obvious, in fact, that they suspected other researchers might already be working to make it a reality. "At the time we thought, 'This is so simple and the time is so ripe,'" recalled Betzig. "There are so many labs that could do this in a week, and we're starting with nothing." But the t...Schepens scientists are first to discover angiogenesis switch inside blood vessel cells
...ius Kazlauskas, who adds that scientists have long suspected an "intracellular" switching process, but until now have known very little about it. "Current drugs focus on suppressing angiogenesis by inhibiting a mechanism outside the vessel cells, which involves the action of growth factors such as VEGF or vasc...Smooth sailing: 'cruise ship virus' tackled by UH, Baylor College of Medicine
...eft and Willson's plan, a biological sample from a suspected Norwalk victim will be placed on a glass slide covered with Norwalk antibodies provided by BCM. An attempt will be made to wash away the sample, but if the virus is present in the sample, it will bond with the antibody and remain on the slide. T...Case Western Reserve University researchers find protein associated with brain cell death
...en the microglia connects with the plaque has been suspected as producing the oxidative damage observed in both...e to the plaque. Oxidative damage has long been suspected as playing an early critical role in AD. Because the events that trigger the beginnings of AD are s......once-in-a-lifetime opportunity." Researchers have suspected since the 1970s that deep reefs lay undiscovered between Miami and Bimini because pieces of reef-building corals had been brought up using surface-operated, dredge-and-grab sampling equipment. However, just as the vast majority of the ocean remains ...Drug discovery team to explore newly discovered deep-sea reefs
... of Biomedical Marine Research. Researchers have suspected since the 1970s that deep reefs lay undiscovered between Miami and Bimini because pieces of reef-building corals had been brought up using surface-operated dredge and grab sampling equipment. However, just as the vast majority of the ocean remains po...Montreal researchers identify defects of immune cells
...iasis. Defective CD4+ T lymphocytes have long been suspected to be the leading cause of candidiasis, however, it never had been directly demonstrated. Now, they become designated targets for the development of novel treatments not only for candidiasis but other mucosal infections." "Secondary infections are ...MIT sheds light on how tumor cells form
...oint proteins for at least 20 years, and they have suspected that mutations in checkpoint proteins cause the ir...ions in aneuploid tumors. "It's puzzling that the suspected culprits - the aneuploidy-inducing checkpoint mutations - are rarely found at the scene of the crime...First human study confirms that immune cells can be a primary cause of bone loss in gum disease
... in periodontal disease. Although researchers had suspected the correlation between bone loss in periodontal (gum) disease and immune cells, this is the first time that this has been confirmed in human tissue samples. With this work, Forsyth scientists and colleagues hope to determine methods for intervening ...DNA: Bacteria's survival ration
... of the pathogens implicated in cystic fibrosis is suspected of feeding on DNA in lung tissue, Finkel said. Biofilms, which have been linked to chronic infections, also may harbor nutritionally competent germs. If researchers succeeded in turning off nutritional competence in such pathogens, as Finkel did in ...UAB researchers confirm HIV-1 originated in wild chimpanzees
... Science magazine. Although researchers have long suspected that HIV-1's origins lie in some way with chimpanzee infection through a closely related virus SIVcpz (simian immunodeficiency virus from chimpanzees), only a few captive apes had been found to harbor SIVcpz. In the study, UAB Professor of Medicine ...Attacking cancer's sweet tooth is effective strategy against tumors
...lls exhibit a high membrane potential. Researchers suspected that was because the cells have switched to an alt... us with an insight into a mechanism that had been suspected in the last six or seven decades," said Leder, John Emory Andrus professor and chair of the Departme...New McGill research shows mice capable of empathy
...il shows that the capacity for empathy, previously suspected but unproven even among higher primates, is also evident in lower mammals. In research published online June 29 in the journal Science, Professor Mogil, graduate student Dale Langford and their colleagues in the Pain Genetics Lab at McGill Universit...Researchers identify genes in fruitflies that may shed light on human cancer spread
...is in animal cancer cells; some that had long been suspected to play a role in cell migration, but have been more difficult to study because their functions are shared by other genes; and some that are well understood for their roles in other cellular functions but without this study would not have been obvi...