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Tag: "suspected" at biology news

Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily

...on, according to the researchers. One role already suspected is that FP-23 attaches to its T cell victim to facilitate a change in the shape of gp41, which in turn drives uptake of HIV RNA and proteins by the T cell. But the Carnegie Mellon work suggests that FP-23 plays another, equally important function — r...

Common cancer gene sends death order to tiny killer

...he McKusick-Nathans Institute of Genetic Medicine, suspected that p53 activates microRNAs like miR-34a because a number of studies have demonstrated that these tiny RNA molecules are frequently abnormal in cancer cells. "P53 is one of the most commonly mutated genes in human cancers," says Mendell. "And the...

Study shows big power of small RNAs, not just proteins, in halting cancer

...mmune response in surrounding healthy cells. Most suspected that proteins would be revealed as key to the power of p53, but this latest research published June 6 by Nature now identifies miRNAs as a critical force behind the anti-proliferation potential of p53. Expression of most miRNAs is reduced in tu...

Newly discovered antibody may be body's natural defense against Alzheimer's

...amyloid antibodies known to be present in IVIG. We suspected there might be another, unseen player." His laboratory studies demonstrated that IVIG initially bound very little single-molecule ("monomer") beta amyloid in a test tube. However, it gathered up much more of the protein when the amyloid was "aged...

Surprising origin of cell's internal highways

... to look at their origins." The Golgi has been suspected to function as an MTOC, explained Kaverina. However, conclusively demonstrating this was impossible before the advent of live-cell imaging techniques that could reveal the true origins of these structures. "The Golgi apparatus is very close to th...

Experts predict Tamiflu could halve the pandemic influenza death toll versus no intervention

...have been in contact with someone who is known, or suspected of being infected with the virus,” commented Professor Ira Longini, Professor of Biostatistics and Mathematics at the University of Washington, Seattle, USA. “This research suggests that a similar approach may also be an effective strategy in the ev...

'Virtual autopsy' helps identify drowning as cause of death

...need for conventional autopsy when drowning is the suspected cause of death," said lead author Angela D. Levy, M.D., from the Department of Radiology, Uniformed Services University of the Health Sciences in Bethesda, Md. The determination of drowning as a cause of death for a body that is found in water is...

An ancient bathtub ring of mammoth fossils

...ence. We’re interested in researching any known or suspected mammoth find, to collected additional evidence and...nd colleagues have identified 62 sites of known or suspected fossil finds and have verified and collected additional material and information at eight of them, i...

Healthy coral reefs hit hard by warmer temperatures

...d lead study author John Bruno at UNC. "We've long suspected climate change is driving disease outbreaks. Our results suggest that warmer temperatures are increasing the severity of disease in the ocean."...

Newly identified mechanism for silencing genes points to possible anti-cancer strategies

...equires extraordinary specificity, however, and we suspected that microRNAs were also acting in some other way to inhibit gene translation into protein. By tracking the associations between molecules involved in generating microRNAs and other molecules in the cell, we uncovered an entirely new pathway, one tha...

Need oxygen? Cells know how to spend and save

...itochondria contain mostly COX4-1. The researchers suspected that COX 4-2 might be the active protein under stressful, low-oxygen conditions, which the researchers refer to as hypoxia. To test the idea, the team compared the growth of human cells in normal oxygen conditions (what's generally present in nor...

Fighting influenza & co. with 40,000 blood samples

...could also be due to a long-forgotten infection. A suspected culprit is the virus causing Pfeiffer's glandular fever, for example. Due to the age group that is mainly affected and a possible path of infection, this disease is also known as 'Students' Kissing Fever'. After the symptoms have disappeared, the pat...

Cold sore virus might play role in Alzheimer's disease

... Aging, add some scientific heft to the idea, long suspected by some scientists, that herpes somehow plays a role in bringing about Alzheimer's disease. The work links a form of the ApoE gene known as ApoE-4, which after advanced age is the leading known risk factor for getting Alzheimer's disease, with the f...

Angelman syndrome deficits rescued in mice

...MKII's prominent role in neuronal function, Weeber suspected that this might account for many of the neurological deficits seen in Angelman syndrome children. Fortuitously, one of Weeber's colleagues ?Ype Elgersma, Ph.D., at Erasmus Medical Center in Rotterdam, Netherlands ?had created a mouse with a mutati...

Scientists find new genes for Crohn's disease

...s, especially Ashkenazi Jews, scientists have long suspected that they have a significant genetic component. Previous genetic studies have found strong links between Crohn's disease and mutations in two genes, one known as CARD15, and, more recently, a gene known as IL23R, which codes for the immune cell re...

New cell type identified in cancer development

... did exhibit stem-like structure. The researchers suspected these unusual cells might be precancerous stems cells and designed several tests and experiments to find out more about them. They selected three pCSC lines and injected them subcutaneously, intraperitoneally or intravenously into three groups of ...

UCLA/Toronto researchers unlock key to memory storage in brain

... member of the UCLA Brain Research Institute. "We suspected it also played a key role in channeling memories to brain cells that are ready to store them." Silva and his colleagues used a mouse model to evaluate their hypothesis. They implanted CREB into a virus, which they introduced into some of the cells...

Scientists uncover new target in cancer mutation puzzle

...iversity of Rochester Medical Center. "But we have suspected for a long time that the way to develop rational searches for new drug targets is to first understand how these oncogenes cooperate. And in this study we've shown for the first time that this idea might work." Land was among the scientists in the ...

Bacteria from patient's dental plaque causes ventilator-associated pneumonia

...eo and colleagues concentrated on three strains of suspected pathogens that are responsible for most hospital-a...olar lavage samples also were collected from those suspected of having developed pneumonia. Samples from nine patients who were found to have the pathogens of...

A revolution in the monitoring of unborn babies

...etuses identified as growing poorly or where it is suspected that the placenta is unhealthy and hence the fetus may become compromised due to lack of oxygen.? In England during 2004 and 2005 17 per cent of inpatient cases for women in NHS hospitals were due to complications of pregnancy or childbirth. By he...

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