Retroviral resistance gene found
...excluded from entering the host cell nucleus. "We suspect that the overexpression of FEZ1 interferes with intracellular trafficking of the viral preintegration complex and traps the viral DNA in the cytoplasm. We hope that learning more about this transport machinery might reveal a new target for antiviral ...Gene expands malaria's invasion options
...o produce a functional protein, and the scientists suspect it had been activated only because it was physically adjacent to PfRh4. Using a second, more quantitative approach, the team found that the two genes were 60- to-80 times more active in the sialic acid-independent parasites than in those that neede...Fluorescing lab worms signal longer life spans
...rs operate completely independently, he said. "We suspect several different biomarkers exist that represent the many different stress-response systems present in an organism," Rea said. "By finding them, we should ultimately be able to find what makes an animal robust to many different insults." Johnson au...$6.5 Million Grant for Microarray Center at Yale School of Medicine
...n the activity of genes other than ramosa1. But we suspect that as the ear got larger, it needed special alleles of ramosa1 to prevent the extra rows from forming branches instead of kernels," says Martienssen. "There may have been other reasons for selecting an unbranched ear, including the interaction with...The genetic origins of corn on the cob
...n the activity of genes other than ramosa1. But we suspect that as the ear got larger, it needed special alleles of ramosa1 to prevent the extra rows from forming branches instead of kernels," says Martienssen. "There may have been other reasons for selecting an unbranched ear, including the interaction with...Study: Harmless virus kills some cancers
...nd inducing cell death," Meyers said. "Although we suspect it is, more studies are needed to determine if the mechanism through which AAV2 destroys cancer cells is the same." Scientists often refer to cancer cells as deregulated, meaning they are no longer acting or communicating like normal, healthy cells....Depression gene may weaken mood-regulating circuit
A brain scan study suggests that a suspect gene may increase susceptibility to anxiety and depression* by weakening a circuit for processing negative emotion. People with the depression-linked gene variant showed less gray matter and weaker connections in the mood-regulating circuit. How well...Immune system's distress signal tells bacteria when to strike back
...ents who undergo major surgery," said Alverdy. "We suspect something very similar, however, occurs in all sorts of infections." Inflammatory bowel disease patients, for example, have elevated cytokines ?the chemical messengers that trigger an immune response ?in the bowel. "These could signal the bug," said...Alien woodwasp, threat to US pine trees, found in N.Y.
...rge dragnet, setting multiple traps in places they suspect the woodwasp may be doing its destructive work. Th...s found in a warehouse in Indiana in 2002. Experts suspect that the female alien that was trapped in Fulton County probably hitchhiked into the area on a woode...Scientists analyze chromosomes 2 and 4
... of any protein-coding genes. However, researchers suspect such regions are important to human biology because they have been conserved throughout the evolution of mammals and birds, and work is now underway to figure out their exact functions. Humans have 23 pairs of chromosomes ?one less pair than chimpan...Bee mites suppress bee immunity, open door for viruses and bacteria
...oduction of GOX decreases. "As mites build up, we suspect that not as much GOX is found in the honey and the honey has more bacteria," says Cox-Foster. "It is likely that the combination of increased mite infestation, virus infection and bacteria is the cause of the two-week death collapse of hives." The m...Gov't Creates Gene Database of Normal Human Tissues
...linicians can use to compare cells and tissue they suspect may have cancerous or other malfunctioning genes. To create these fingerprints, Khan and his team assembled a complementary DNA (cDNA) microarray, using a pair of glass slides on which thousands of known genes have been printed in tiny spots. Cells c...Researchers find gene that may be at root of potato blight
Researchers have found a gene they suspect plays an important role in triggering the blight that wiped out Ireland's potato crops a century-and-a-half ago. And the pathogen that contains this gene still causes massive amounts of agricultural damage throughout the modern world?on the order of...Newly Discovered 'Branding' Process Helps Immune System Cells Pick Their Fights
...eved to play a role in atherosclerosis. Scientists suspect oxidative damage in the blood vessel walls may lead to immune reactivity that contributes to narrowing and stiffening of blood vessels. ### Herzog J, Maekawa Y, Cirrito TP, Illian BS, Unanue ER. Activated antigen-presenting cells select and present...Hydrogen and methane provide raw energy for life at 'Lost City'
...nt or invisible shells so it's no wonder we didn't suspect the actual diversity," says Kelley, who was chief scientist on the expedition, which like the 2000 voyage was funded by the National Science Foundation. Other large organisms include crabs, corals and fish. Kelley will be co-principal investigator o...Discovery clarifies role of peptide in biological clock
...neurons are specialized circadian pacemakers. "We suspect that at least some of the pace making cells in the SCN are VIP cells, and one of the things we'll try to do next is confirm this. We will also try to understand better how VIP synchronizes pacemakers," he said. It is surprising that the process is r...Migratory songbirds have a specialized night-vision brain area
...r night-time flight," Jarvis said. The researchers suspect that the newly discovered brain region could be involved in processing and integrating light-dependent magnetic compass information and star compass information; and thus may be responsible for the impressive navigational abilities of birds migrating...Oceans more vulnerable to agricultural runoff than previously thought, study finds
...ystem by depleting oxygen in the water. Scientists suspect that many harmful blooms are artificially fueled by fertilizer runoff from farms, which dump tons of excess nitrogen into rivers that eventually flow into the sea. "There has been an international effort to try to understand the productivity of the ...Brain Scans Reveal How Gene May Boost Schizophrenia Risk
Clues about how a suspect version of a gene may slightly increase risk for schizophrenia* are emerging from a brain imaging study by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH). The gene variant produced a telltale pattern of activity ......at histatin was significantly less active when the suspect target was missing. Further research indicated that histatin binding to the target protein killed the fungal cells by preventing it from regulating its ions, the positive and negative charged molecules that move into, and out of, cells. Ions regulat...